House vacation rentals in La Mesa
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Top-rated house rentals in La Mesa
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for La Mesa house rentals
House rentals with a pool
Home in La Mesa
4.93 out of 5 average rating, 106 reviewsUpdated TownHome, Great Location, Fantastic Views
Feb 16 – 23
Home in La Mesa
4.96 out of 5 average rating, 137 reviewsHeated pool, outdoor fire pits, chef's kitchen
Sep 28 – Oct 5
Home in La Mesa
4.99 out of 5 average rating, 127 reviewsMid-Century Style Family House with Spa
Jun 7 – 14
Home in La Mesa
4.87 out of 5 average rating, 130 reviewsThe Queen House
Jul 25 – Aug 1
Home in La Mesa
4.81 out of 5 average rating, 132 reviewsSunny SD/La Mesa Updated '24-Pool-4 bed-Sleeps 10
Oct 5 – 12
Home in El Cajon
4.97 out of 5 average rating, 134 reviewsBeautiful 3,000 Sq Ft Tropical Oasis
Sep 26 – Oct 3
Home in San Diego
4.9 out of 5 average rating, 116 reviewsSan Diego Getaway W/Pool & Hot tub! Sleeps 8!
Oct 28 – Nov 4
Home in San Diego
5.0 out of 5 average rating, 139 reviewsMidcentury Lux 4BR home with Pool, Spa & Cabana
Nov 1 – 8
Weekly house rentals
Home in La Mesa
4.96 out of 5 average rating, 493 reviewsClean 1BR/1BA Guest House Peaceful Private Casita
Jun 12 – 19
Home in San Diego
4.9 out of 5 average rating, 126 reviewsModern & Romantic Studio | Private Entrance
Jan 4 – 11
Home in San Diego
4.94 out of 5 average rating, 133 reviewsDesirable North Kensington+Quiet+Allergen Free
Oct 5 – 12
Home in San Diego
4.88 out of 5 average rating, 153 reviewsPrivate cottage walkable to restaurants and bars
Oct 11 – 18
Home in San Diego
4.91 out of 5 average rating, 157 reviewsHawk's nest - wakeup to nature - Hillcrest
Feb 24 – Mar 3
Home in La Mesa
4.95 out of 5 average rating, 111 reviewsCheery & Roomy Family Home w/Master Suite, Fence
Apr 1 – 8
Home in San Diego
4.91 out of 5 average rating, 159 reviewsCute Small House
Sep 30 – Oct 7
Home in San Diego
4.9 out of 5 average rating, 364 reviewsComfy 2Br Craftsman House in the Heart of SD
Mar 16 – 23
Private house rentals
Home in San Diego
4.9 out of 5 average rating, 101 reviewsCozy 2Bed-Private Parking, Dog Friendly, Big Yard!
Nov 7 – 14
Home in Lemon Grove
4.99 out of 5 average rating, 117 reviewsCOZY King Bed: Very clean, Quiet, safe, brand new
Oct 1 – 8
Home in Bonita
5.0 out of 5 average rating, 155 reviewsMulberry House..convenient to San Diego and Mexico
Dec 19 – 26
Home in San Diego
4.97 out of 5 average rating, 259 reviewsFun & Funky TINY House for 2 North Prk/Hillcrest
Dec 18 – 25
Home in La Mesa
4.96 out of 5 average rating, 52 reviewsCozy, Single Bedroom, Detached Guest House
Aug 30 – Sep 6
Home in El Cajon
5.0 out of 5 average rating, 7 reviewsCozy 1BR Home with Lovely Front Yard
Nov 24 – Dec 1
Home in La Mesa
4.97 out of 5 average rating, 35 reviewsGarden Studio (40% long, 15% short term discount!)
Jan 29 – Feb 5
Home in El Cajon
4.98 out of 5 average rating, 89 reviewsSuite Charles Way: A Cozy Fletcher Hills Studio
Aug 10 – 17
Quick stats about house rentals in La Mesa
Total rentals
280 properties
Rentals with dedicated workspaces
170 properties have a dedicated workspace
Rentals with a pool
80 properties have a pool
Pet-friendly rentals
90 properties allow pets
Family-friendly rentals
190 properties are a good fit for families
Total number of reviews
9.5K reviews
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