Wheelchair accessible vacation rentals in Upstate South Carolina

Find and book unique wheelchair accessible rentals on Airbnb

Top-rated wheelchair accessible rentals in Upstate South Carolina

Guests agree: these wheelchair accessible rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Apartment in Sapphire

4.92 out of 5 average rating, 148 reviews

Beautiful Cozy Mountain Retreat

This beautiful space is a large, 1600 sq foot downstairs basement apartment, with a private entrance through the shared garage. It is a quiet peaceful area and is conveniently located nearby unique shopping in Cashiers, as well as beautiful gorgeous hikes, waterfalls. and lakes. An outdoor deck circles the entire length of the apartment and many windows provide a beautiful view of the mountain. At the Wyndham Resort and for $9 per person you may have access to all their amenities for 3 days.

Guest favorite

Guesthouse in Asheville

4.88 out of 5 average rating, 593 reviews

Charming Apartment on Private Land

Enjoy the privacy of your own space in a beautiful country setting less then 10 miles from the heart of downtown Asheville: approximately a 15 min drive, often less! It’s truly like traveling between two worlds in a remarkably small amount of time. Our location offers you the ability to easily access all that Asheville has to offer with a quiet retreat to return to when you’ve had enough. In between activities take a relaxing stroll on the 30 miles of manicured trails, only a 2 min walk away!

Guest favorite

Farm stay in Baldwin

4.95 out of 5 average rating, 112 reviews

Life on the farm, with a pool! 1.5 Hrs to Atlanta

Drive down our driveway and just feel the stress leave you as you breathe the fresh country air! New for 2024, we added a miniature Ginny (donkey) think her ears are as tall as she is to the petting area next to the apartment More baby goats due in the Spring On clear cool nights, milk way is SO easy to see. We are often in the path of the ISIS!! You can lie in bed and watch the babies and their moms! Bring the dogs & let them run free Otherwise just bring yourself & enjoy God's Country!

Guest favorite

Home in Hayesville

4.98 out of 5 average rating, 328 reviews

Mountain House Rental at the Lake

This is a four season vacation spot. Create your own memories in the western North Carolina mountains by Lake Chatuge! Enjoy great hiking, boating, fishing, and much more! Take advantage of the hiking and biking on the Jack Rabbit Mountain trails along the shores by Lake Chatuge. Winter discounts available from January 1 until March 20. OPTIONAL MINI COTTAGE (for a third bedroom that sleeps 2) with Queen sized bed and TV but no extra bathroom for an extra $25 per night plus $25 cleaning.

Superhost

Guest suite in Asheville

4.85 out of 5 average rating, 511 reviews

Private studio near downtown, Biltmore & breweries

Clean and comfy, bright and cozy studio with gorgeous bamboo floors just 7 minutes to downtown, walking distance to Biltmore Village, 5 minutes from 8 major breweries and the Biltmore Estate! Check out all my awesome reviews, this is the real deal, I'm a Super Host for a reason! Full size memory foam bed. TV/DVD with a Roku and 300 DVD's and wifi. Private/separate unit with private entrance and parking, quiet neighborhood. Great for couples or solo travelers, can fit a small family.

Guest favorite

Home in Clarkesville

4.95 out of 5 average rating, 517 reviews

Welcome to Grandma's House

My place is close to Smoky Mountains, Helen, Tallulah Gorge, waterfalls, hiking trails, mountain lakes, hour from Atlanta, parks, great views, restaurants, art and culture. World class trout fishing just 20 minutes away, where I caught my 10 lb., 26" one! I welcome couples, solo adventurers, families (with kids), and big groups. Popular hiking trails and waterfalls are just 3 miles away. Handicapped accessible, including shower. TV with dozens of DVD movies, no cable or satellite.

Guest favorite

Apartment in Flat Rock

4.92 out of 5 average rating, 469 reviews

Forest River/Apt w/Hot Tub & Fireplace

Drive through apple orchards and winding mountain roads to get to this 2-acre secluded, wooded site with a pond on a trout-stocked river. A year-round property We now sanitize the apartment with ozone. I'm told this kills bacteria and viruses. Amenities include a fireplace, 43" TV, satellite internet, complete kitchen, hot tub, propane grill, and outdoor showers. Hendersonville is 15 min. and the Asheville airport is about 18 min. Asheville is between 20 to 30 minutes away.

Guest favorite

Bungalow in Brevard

4.97 out of 5 average rating, 145 reviews

Lumberyard Bungalow - Downtown Brevard

Lumberyard Falls, located in the Lumberyard Arts District, 2 blocks from Downtown Brevard, is newly renovated but still maintains all of the charm of a 1940s cottage. Our bungalow features all new furniture, comfortable beds with brand new mattresses and high quality linens. The backyard is shady and peaceful, with a soothing water feature, fire pit, and seating for four. One level, easy access, with driveway and detached one car garage for storing bikes and gear.

Guest favorite

Apartment in Sylva

5.0 out of 5 average rating, 178 reviews

Studio Apartment with kitchen VERY close to WCU

The Studio apartment on top of Catamount Gap is in a large home 1.5 miles from Western Carolina University. Great for WCU visits (we both taught there) Ideal for traveling motorcyclist (we're bikers too) or anyone who enjoys day trips roaming around western NC. Handicapped accessible. PLEASE NOTE: This a a 100% non smoking property. No smoking of any substance anywhere on the entire property to include outside areas. Simply non smoking

Guest favorite

Cottage in Athens

4.97 out of 5 average rating, 377 reviews

DesignerCottage-Heart of 5 Points 2BR1Bath+Kitchen

This historic stone guest cottage is located in the heart of Five Points, walking distance to many Athens jewels: The Five and Ten, The Royal Peasant Pub, Condor Chocolates, Jittery Joe's, Earthfare and Independent Bakery, also blocks from UGA campus and the football stadium. Close parking for Georgia Football events PLEASE Do Not Request False Dates - For inquiries, go to "Meet MY Host" and "Contact," without selecting dates.

Guest favorite

Guest suite in Hartwell

4.97 out of 5 average rating, 210 reviews

Relaxing retreat on Lake Hartwell.

NEW IN 2021: New carpet, paint and mattress! Our one bedroom "apartment" has everything you need for a relaxing getaway. Room for air mattresses too. There is swimming, fishing, kayaking, and just plain relaxing here. We are close to hiking and waterfalls. Approximately one hour from UGA or one hour from Clemson for a getaway football weekend. Come enjoy and bring your pets too—they are always welcome!

Guest favorite

Home in Greenville

4.86 out of 5 average rating, 211 reviews

⭐️ Comfy Eastside Home Close to Downtown ⭐️

Welcome to this 3 bedroom 2 full bath home in a quiet neighborhood (Heritage Hills) adjacent to Botany Woods and within minutes to Downtown Greenville, Haywood Mall, Bob Jones University, Furman University, and countless restaurants and opportunities for nightlife. The home is very tastefully decorated to make you feel like you’re at home. Large fenced yard. Access to Netflix, Hulu, and Disney+