Skip to content

South Carolina vacation rentals

Book unique homes, vacation rentals, and more on Airbnb

Top-rated vacation rentals in South Carolina

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

Superhost
Cottage in Hardeeville
Tranquil Savannah River Cottage w/ Views+Breakfast
Awaken to Savannah River views from the loft, enjoy the expansive 2x decks, full wall sliding glass/screened doors, 2 wooded acres strung w/ Spanish moss & relaxing as the water hits the docks. Bring a book, fish, or hike the preserve! Enjoy breakfast, snacks, gas BBQ, firepit, screened in pergola+fans, fast wifi & SmartTV! Featured in travel magazine! Near Savannah, Hilton Head, I95 & airport! This adorable, smaller cottage is perfect for special occasions or to get away! Click pics and book!!
$171 per night
Superhost
Home in Saint Helena Island
Updated treehouse with spectacular views on Fripp
Our cozy getaway on Fripp Island near the beach is a perfect retreat to unwind and relax. It provides a tranquil escape from the noise and chaos of everyday life, allowing you to enjoy the serene beauty of Fripp Island. Spend your days lounging in the hammock taking in the spectacular saltwater marsh views, sunbathing on the beach, exploring the island on the bicycles, or just sitting in the lanai with a book, our private oasis in the trees can cater to your needs.
$183 per night
Superhost
Shipping container in Walhalla
The Valhalla Sky Suite at Hi Saw Gap
Soar above the canopy of Sumter National Forest in this one of a kind container home, located 0.5 miles from Stumphouse Tunnel, Issaqueena Falls, Yellow Branch Falls hiking trail, and the World class Stumphouse Mountain Bike Park. Unwind after a day of exploring the waterfalls and parks of Upstate SC in your private spa in the sky, or cash in every penny of your million dollar view from the balcony bar and deck. All are welcome!
$203 per night

South Carolina beach vacation rentals

Superhost
Apartment in Myrtle Beach
NEW Bed nook overlooking ocean!
$199 per night
Condo in Myrtle Beach
Oceanfront Bliss | Luxurious Getaway
$87 per night
Condo in Myrtle Beach
WOW TROPICAL INDOOR/OUTDOOR SUNDECK/KING/SLPR/FIRP
$125 per night
Superhost
Condo in Hilton Head Island
Beach Resort 3rd NT FREE Partial OceanView KingBed
$119 per night
Superhost
Condo in Myrtle Beach
Luxury King OceanFront Suite
$136 per night
Condo in Hilton Head Island
Harborfront Hilton Head Condo with Sunset Views!
$99 per night
Superhost
Condo in Hilton Head Island
Ocean Front Resort Villa
$128 per night
Superhost
Cottage in Saint Helena Island
Cute Cottage Next to Hunting Island.
$121 per night
Superhost
Apartment in Charleston
Private Waterfront Apartment Among The Grand Oaks
$117 per night
Superhost
Condo in Hilton Head Island
Beach Resort-OceanView Villa-Stylish Total Remodel
$115 per night
Superhost
Condo in Myrtle Beach
Patricia Grand Resort 1802 - Ocean Views
$120 per night
Superhost
Condo in Hilton Head Island
Newly remodeled! Stylish HHBT Condo. Ocean view!
$125 per night

South Carolina home rentals

Superhost
Home in Greenville
Cozy Treehouse
$250 per night
Superhost
Home in Easley
“Lake House Paradise” Waterfront Oasis
$134 per night
Home in Fair Play
Waterfall Cove - East
$142 per night
Superhost
Home in Charleston
Private Lowcountry Cottage
$89 per night
Home in Anderson
Lakefront dock *Hot tub* Anderson Clemson new
$180 per night
Superhost
Home in Chapin
Lake Murray Panoramic Views & private dock
$279 per night
Superhost
Private room in Summerville
Home Away From Home with PRIVATE ACCESS!
$65 per night
Superhost
Home in Edisto Island
Marshfront Villa In The Trees - Near Beach & Bay
$283 per night
Home in Hilton Head Island
Luxe Treetop Escape w/ Fire Pit & Ocean Views!
$281 per night
Superhost
Home in Greenville
The Peacock - Spa Bath - No Cleaning Fee
$169 per night
Superhost
Home in Anderson
Sunset Point-Best view on Broadway - HOT TUB!
$224 per night
Superhost
Home in Little River
Best of North Myrtle Beach & Little River
$127 per night

South Carolina treehouse rentals

Superhost
Treehouse in Travelers Rest
The Forestry House - A modern luxury treehouse.
$289 per night
Superhost
Treehouse in Walhalla
The Majestic Treehouse romantic, luxury retreat
$458 per night
Superhost
Treehouse in Mountain Rest
THE BELLA LUNA Romantic Mountain Treehouse
$269 per night
Superhost
Treehouse in West Columbia
Luxury Treehouse in the heart of Columbia
$250 per night
Superhost
Treehouse in Marion
Enchanting Treehouse with Modern Amenities
$254 per night
Superhost
Treehouse in Hilton Head Island
Sea Pines Coastal Chic Treehouse
$243 per night
Treehouse in Johns Island
Waterfront Treehouse
$286 per night
Superhost
Treehouse in Fort Mill
ROYAL GOOSE 1- bedroom treehouse.
$149 per night
Superhost
Treehouse in Greenville
The Nest-Cozy Private Treetop studio w/large deck
$135 per night
Superhost
Treehouse in Hilton Head Island
Sea Pines Coastal Chic Sealoft at 2031 Deer Island
$161 per night
Superhost
Treehouse in Beaufort
Private island Treehouse
$175 per night
Superhost
Treehouse in Mountain Rest
THE STELLA VISTA Romantic Mountain Treehouse
$262 per night

Your guide to South Carolina

Welcome to South Carolina

Weeping Spanish moss cloaks the cobblestone streets and historic homes of South Carolina’s oldest cities while its coast beckons travelers from near and far. South Carolina is one of the original 13 colonies of the United States, and it resisted British authority. Perched on the coast just north of Savannah, Charleston has been a major port city since the Spanish first settled the area in the 16th century, and was hotly contested territory in subsequent wars. Remnants of this history still stand in places like Fort Sumter and Fort Moultrie. South Carolina’s draws are heavily clustered around coastal areas like Hilton Head and Myrtle Beach — or on waterways that connect to the sea — but there’s plenty to do and see in its inland cities like the state capital of Columbia and the cultural hotbed of Greenville.


The best time to stay in a vacation rental in South Carolina

As one of the southernmost states on the Eastern Seaboard, South Carolina maintains a mild climate year-round, making it an ideal destination no matter when you’re visiting. Summer months are popular at the beaches, so avoid traveling in June, July, and August if you want to escape the crowds. Fall and spring are traditionally beautiful, and a bit cooler, though still T-shirt weather. Keep hurricane season in mind when planning your trip to South Carolina; it runs June through November along the Atlantic coast. Winter, which happens to overlap with oyster season, can be a pleasant time to visit due to the lack of crowds, though some businesses in coastal areas may close seasonally.


Top things to do in South Carolina

Charleston

With its cobblestone streets and antebellum architecture, Charleston is one of the most charming cities in the American South. A peninsula town whose rivers empty into the Atlantic Ocean, it has a warm, welcoming vibe where visitors are treated like family, and just about anywhere you go somebody is eager to fill your cup with a heavy-handed pour of spiked sweet tea. If you want to combine urban travel with a beach getaway, Charleston is the place for you; its downtown core occupies a tight grid of streets and historic homes with thriving beach communities — Folly Island to the west and Isle of Palms and Sullivan’s Island to the east — on each side.

Congaree National Park

Wildlife enthusiasts, hikers, and paddlers will want to add South Carolina’s only national park, just south of Columbia, to their itinerary. The Congaree and Wateree rivers snake their way through the bottomland hardwood forest, part of the Congaree International Biosphere Reserve, making it a great place to observe the unique ecosystems by kayak via its waterways.

Greenville

In the northwestern corner of the Palmetto State near the Blue Ridge Mountains, Greenville is a melting pot of lifestyles: a city made for epicures and art lovers that also places heavy emphasis on outdoor living. While Falls Park on the Reedy is Greenville’s centerpiece, it’s not the only waterfall in town: Greenville boasts more than 30 breathtaking cascades, three state parks, and the 22-mile, multi-use Prisma Health Swamp Rabbit Trail.