Lake house vacation rentals in South Carolina
Find and book unique lake houses on Airbnb
Top-rated lake house rentals in South Carolina
Guests agree: these lake houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for South Carolina lake house rentals
Waterfront lakehouse rentals
Home in Waterloo
4.92 out of 5 average rating, 126 reviewsBest Lake Front w Floating Dock/Firepit-Sleeps 10
Sep 3 – 10
Home in Inman
4.99 out of 5 average rating, 148 reviewsLAKE LIFE...
Nov 6 – 13
Home in Anderson
4.93 out of 5 average rating, 149 reviewsBroadway Lake Retreat in Anderson, SC
Oct 23 – 30
Home in Inman
4.95 out of 5 average rating, 102 reviewsCasa del Lago...Come Relax...You are on Lake Time!
Mar 22 – 29
Home in Chapin
4.9 out of 5 average rating, 101 reviewsLake Murray Family Retreat | BIG Water View Chapin
Jan 8 – 15
Home in Myrtle Beach
4.91 out of 5 average rating, 187 reviewsPrivate Beach Paradise in Ocean Lakes w/ Golf Cart
Feb 23 – Mar 2
Home in Modoc
4.93 out of 5 average rating, 104 reviewsIvy’s Escape (water front) at Lake Thurmond
Jun 6 – 13
Home in Ridgeway
4.96 out of 5 average rating, 109 reviews3000 sq ft lake house with views from every window
Nov 3 – 10
Pet-friendly lake house rentals
Home in Bluffton
4.98 out of 5 average rating, 122 reviewsOld Town Bluffton Cottage - Includes Golf Cart!
Feb 27 – Mar 6
Home in Greenville
4.99 out of 5 average rating, 133 reviewsPark Cottage at State Park -15min Dwtn GVL, Furman
Sep 8 – 15
Home in Easley
4.92 out of 5 average rating, 133 reviewsLarge lake house - 15 min to Downtown Greenville
Feb 16 – 23
Home in Lexington
4.87 out of 5 average rating, 143 reviewsLake Murray Paradise~2 BR, 1 Bth, Kit/Living area.
Aug 9 – 16
Home in Inman
4.97 out of 5 average rating, 117 reviewsBeautiful Lakefront Home on Over an Acre
Jan 4 – 11
Home in Hilton Head Island
4.89 out of 5 average rating, 107 reviewsLuxe & Fun Family Gem ~ Walk to Beach ~ Pool ~ BBQ
Oct 6 – 13
Home in Cross Hill
4.87 out of 5 average rating, 151 reviewsA great time!
May 22 – 29
Home in Anderson
4.99 out of 5 average rating, 137 reviewsLake House, close to Clemson Kayaks & Paddleboards
Jul 7 – 14
Private lake house rentals
Home in Gilbert
4.95 out of 5 average rating, 133 reviews10 Mile View on Lake Murray w/ Dock and Ramp
Oct 1 – 8
Home in Tamassee
5.0 out of 5 average rating, 24 reviewsWhitewater Lake Front Cottage
Oct 20 – 27
Home in Camden
5.0 out of 5 average rating, 61 reviewsBest Wateree Sunsets, many amenities w/ king bed!
Nov 22 – 29
Home in Ninety Six
5.0 out of 5 average rating, 23 reviewsLakefront Retreat
Aug 2 – 9
Home in Summerton
5.0 out of 5 average rating, 80 reviewsCheerful 3 bedroom home on the lake
May 9 – 16
Home in Beaufort
4.92 out of 5 average rating, 12 reviewsThe Grey Pearl on Port Royal's Battery Creek
Nov 22 – 29
Home in Branchville
4.93 out of 5 average rating, 29 reviewsEdisto River Turnhole Getaway
Sep 3 – 8
Home in Inman
5.0 out of 5 average rating, 25 reviewsLakeside Family Home w/Dock, Deck & Paddle Boards
Sep 5 – 12
Destinations to explore
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