Bed and breakfast vacation rentals in Upstate South Carolina

Find and book unique bed and breakfast rentals on Airbnb

Top-rated bed and breakfast rentals in Upstate South Carolina

Guests agree: these bed and breakfast rentals are highly rated for location, cleanliness, and more.

%{current} / %{total}1 / 1
Guest favorite
A small, modern tiny home is set among trees, featuring a brown and gray exterior with wooden shingles. The yellow front door is framed by a wooden ramp, offering accessible entrance. Natural stone gravel surrounds the structure, enhancing the rustic feel of the woodland setting.
Tiny home in Bryson City
4.94 out of 5 average rating, 32 reviews

"Tohidu" tiny home on 11 acre pastoral farm

Farmstay Bed and Breakfast. Wing & Hoof Mountain Escape (Facebook, Google, and wingandhoof.com) Child & Pet friendly (pets with a fee). Quick 5 minute drive to town and grocery store. 11 acres of Tranquility. Interaction with guests to your preference. Very unique experience. Check out all of our listings. Hot Breakfast included. Fires, grills, complementary drinks, cookies, snacks & fixings for Smores. Ask about snacking the animals. Indoor and outdoor games and toys. Easy access year round.

Top guest favorite
An inviting outdoor space features a large in-ground saltwater pool surrounded by lush greenery. Comfortable lounge chairs and umbrellas provide shade, while a gazebo stands in the background. The neatly manicured lawn enhances the tranquil setting, creating an ideal area for relaxation.
Home in Greenville
4.99 out of 5 average rating, 166 reviews

Palmetto Escape - Serene- Pool- 6.6 mi DTWN GVL

Beautiful, updated 2 story home on secluded fenced in resort-like half acre. In-ground saltwater pool. Gazebo with mosquito netting, ceiling fans and lighting. Keyless entry. Bedrooms are upstairs, all include Smart TVs and workspaces. High-speed Internet. Bathrooms w/a variety of amenities. Laundry Room. Fully stocked kitchen and propane grill. Perfect for family escapes, working professionals, outdoor adventurers, sports fans, child friendly. 2 car garage. Quite, residential neighborhood.

Guest favorite
The modern cottage features a striking dark exterior complemented by an orange front door. A stone pathway leads to the entrance, framed by windows that provide ample natural light. Lush greenery surrounds the home, enhancing its welcoming presence.
Home in Tryon
4.87 out of 5 average rating, 113 reviews

2 min to TIEC The Orange Door 3br 2ba LUXE Cottage

A very special modern cottage in the heart of horse country and in TIEC's back door! Superb hi-quality details with beautiful light and an artistic feel. 3 mins to the front gate, close to Landrum, Columbus, Tryon, Asheville, Greenville, Lake Lure, and Charlotte. Has a boutique hotel feel and amenities, PEACE & QUIET, full kitchen, office space, fireplace, cute bathrooms, and deck with view. Available for short stays or long-term seasonal rentals. Extr. charge for each add guest over 4.

Guest favorite
A serene view of distant mountains is captured under a soft, hazy sky. Lush greenery blankets the valley below, with low clouds drifting across the landscape. The tranquil scene invites relaxation and appreciation of nature.
Private room in Maggie Valley
4.93 out of 5 average rating, 348 reviews

Holly Tree Bed & Breakfast - Maggie's Room

Holly Tree B & B is located in the heart of Maggie Valley, with stunning views, looking out over the valley and mountains. We have a glass enclosed and screened porch from which to enjoy the view, with rockers and swings for comfort. All bedrooms have private baths with a tub/shower combination. Convenient to Festival Grounds, Asheville, Cherokee, with hikingand fishing. We offer full and varied breakfasts. We have two small Pomeranians who love everyone, but can keep them isolated.

Top guest favorite
A cozy seating area features a light-colored sofa adorned with neutral pillows. Nearby, a well-equipped kitchen with dark green cabinetry is visible, showcasing various kitchen utensils and small appliances. Natural light enters through windows, highlighting the modern design.
Guest suite in Abbeville
5 out of 5 average rating, 106 reviews

Cozy Haven Guest Suite – Retreat in Abbeville

Welcome to The Haven! A quiet, cozy retreat minutes from downtown Abbeville. Arrive to a spotless private space with fast Wi-Fi, smart TV, coffee station and plush queen bed. Mini split AC keep things comfy year-round. Why guests love us: Superhost & guest-favorite service -Private entrance & parking -1-hour average response time. Book your relaxing stay today before the popular dates disappear! Outdoor seating & fire pit Equipped kitchenette No smoking. Hypoallergenic dogs ONLY.

Top guest favorite
A spacious bedroom features two comfortable beds, each adorned with soft linens and decorative pillows. A soft glow is emitted from a stylish bedside lamp, while two modern accent stools are positioned at the foot of the beds against a neutral-colored wall.
Private room in Central
4.99 out of 5 average rating, 161 reviews

Eagles Rest (Room 1) Near Clemson!

Eagles Rest is a quiet Bed & Breakfast nestled in the heart of Central, SC. It's cozy setting and close proximity to area lakes, hiking trails, university activities, and more, is the perfect place to provide home away from home while you visit the upstate. Our mission is to practice the principle of 1 Peter 4:8-9 which says "Above all, love each other deeply...offer hospitality to one another..." We believe providing a place for retreat is a perfect way to spend your time away!

Guest favorite
The two-story white house showcases a symmetrical facade with large windows and an inviting front porch. Vibrant shrubs and flowers provide pops of color in the courtyard, while an American flag gently flutters near the entrance. Lush, green trees frame the home, enhancing the natural beauty.
Home in Shelby
4.95 out of 5 average rating, 19 reviews

The Hunt House Bed and Breakfast

The Hunt House was the beautiful home of Dr. Robert Lee Hunt of Lattimore, NC. It is on 6 acres of pasture and only 3.8 miles from the Washburn Switch Industrial Park. The house is fully furnished with 5 Handmade heart pine, cherry, and walnut bedroom suites, and has 5 bathrooms. The house has hardwood floors in most rooms, and antique furniture throughout the house. The house has a functional fireplace, and a large porch with 8 rocking chairs, that overlook the yard.

Top guest favorite
The interior features a spacious kitchen with rustic cabinetry, a large island, and vintage appliances. Natural light floods through the windows, illuminating the unique ceiling beams and wood flooring. The outdoor patio is visible, offering dining options and a serene mountain backdrop.
Cabin in Waynesville
4.98 out of 5 average rating, 292 reviews

One-of-a-Kind Rustic Mountain Studio-Private Quiet

This mountain cabin is a true escape! Nestled on 16 acres in the mountains overlooking a 6088ft peak, it's the perfect get-a-way. Inspired with a rustic Italian Villa in mind. Private & quiet- The cabin is 7 min. from shops & restaurants of Waynesville & 30 mins to Asheville. Our brand new restored studio cabin is custom designed by local artisans & is a place you can come to unwind, decompress (really), & explore the beautiful mountains of the Great Smokies!

Guest favorite
An aerial view captures a modern home with a red and gray exterior, featuring multiple large windows. Nearby, a guest house is visible, surrounded by colorful autumn foliage. The landscape includes a fenced area, accentuating the serene, wooded surroundings.
Home in Whittier
4.97 out of 5 average rating, 30 reviews

Great Smoky Mtns- Casino- Outdoor Adventures

Luxury new home with detached guest house Quiet, secluded with beautiful wooded surroundings. Paved road. Accessible to motorcycles. 1 hour West of Asheville Airport 10 minutes to Dillsboro and Tuckaseegee River 15 minutes to -Sylva and Bryson City -shopping districts, local restaurants & breweries -Harrah’s Casino & Family Multiplex -Great Smokey Mountain National Park 30 minutes to -Nantahala Outdoor adventure area -Cataloochee Ski area-Maggie Valley

Guest favorite
Private room in Anderson
4.96 out of 5 average rating, 46 reviews

The Tiger's Suite Picket Fence Lodge Pickleball

Picket Fence Lodge B&B! Are you a coming in on business. Ask about our CORPORATE WEEKLY RATES. The Tiger's Den Suite, includes 2 twin beds, mini fridge, and private full bathroom with shower, cozy sitting/work area and free WIFI. Well behaved small dogs welcome. The Lodge has a living room with wood burning fireplace for guests to enjoy before going out to dinner to one of our many fine restaurants within minutes of the Lodge.

Top guest favorite
The exterior of the property is showcased, featuring a charming single-story house surrounded by lush greenery. Large windows allow natural light to fill the space, while a neatly maintained garden with blooming flowers is visible in the foreground.
Private room in Greenville
4.97 out of 5 average rating, 229 reviews

B & B/Downtown/Furman/BJU/1

Minutes to DOWNTOWN GREENVILLE! FALL SPECIAL RATES🍂🍁Do you LOVE NORTH Greenville? Then come visit our Homey 4 Room B & B we would love to host! Comfy room & loaded tv! Enjoy self serve Continental Breakfast/Fresh Brewed Coffee/Hot Tea Bar. Minutes to Downtown, Bon Secour, Swamp Rabbit Trail, Furman & Bob Jones University’s. 🚨Secure parking. Our property is completely fenced in. You will have to open the gate to access.

Guest favorite
Private room in Waynesville
4.96 out of 5 average rating, 68 reviews

Chloe's Room-Walk to Restaurants/Pubs/Shops

Come and enjoy a room in this beautiful 1907 farmhouse. Escape the extreme cold from further up north. We are a 5 to 10 minute walk to Main Street. (Depending on your walking speed). Come enjoy all the shops, art galleries, pubs and array of restaurants. You’ll love Twin Maples because of the wonderful wood work, high ceilings and wrap-around porch. You are in town; but it has the feel of being in the country.

Popular amenities for Upstate South Carolina bed and breakfast rentals

Destinations to explore