
Guesthouse vacation rentals in San Luis Obispo
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Top-rated guesthouse rentals in San Luis Obispo
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for San Luis Obispo guesthouse rentals
Family-friendly guest house rentals

California central coast 2-bedroom haven

Cambria - under the Coral Tree

Huge 2 br 2 ba Guest House sleeps 6

The Boathouse, a refreshing get away.

Pet Friendly Garden Cottage 2 Bdrm + Loft

Wine Country Casita

Private SLO Lodge: Gym, Sauna, Views, Wineries!

Windmill Lane-Beautiful Country Tree-Lined Retreat
Guest house rentals with a patio

Private top floor spacious 1 bedroom retreat

The Cozy Casita

The Shed

Maverick Bungalow

Jersey Joy Cottage Farm Stay

Deerfield Cottage on Paso's wine road

Central Coast Guest House - Private entrance

McClellan Cottage - centrally located studio
Guest house rentals with a washer and dryer

Wine Country Escape - Cozy, comfortable 3 bedroom

Bright, Airy and Beautifully Built!

Studio on Oak

A Cozy Loft in Templeton

Winemaker's Rural Hideaway in the Heart of Paso Robles

Cottge On The Crt: Tennis/Picklball, Hike, Winery

Beautiful Private Barn , In Country

Rustic Rural Ranch House
Quick stats about guesthouse rentals in San Luis Obispo
Total rentals
30 properties
Nightly prices starting at
$80 before taxes and fees
Total number of reviews
5.1K reviews
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Wifi availability
30 properties include access to wifi
Popular amenities
Kitchen, Wifi, and Pool
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- Cayucos Beach
- Cayucos State Beach
- Moonstone Beach
- Hearst San Simeon State Park
- Morro Strand State Beach
- Montaña de Oro State Park
- Dairy Creek Golf Course
- Minuteman Beach
- Natalie's Cove
- B & E Vineyard & Winery
- Pismo State Beach
- Wall Beach
- Allegretto Wines
- Pirates Cove Beach
- Spooner's Cove
- Mission San Luis Obispo de Tolosa
- Point Sal State Beach
- Au Bon Climat
- Paradise Beach
- Bovino Vineyards
- Moonstone Beach
- Olde Port Beach
- Coon Creek Beach
- French Camp Vineyards
- Things to do San Luis Obispo
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- Family travel hub Tips and inspiration
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