
House vacation rentals in Seneca
Find and book unique houses on Airbnb
Top-rated house rentals in Seneca
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Seneca house rentals
House rentals with a pool

Lakefront Oasis, Dog-Friendly Fenced in Yard.

the TRail house | 4Bdrm Biker's Paradise w/ Pool

Lake Hartwell: Private Pool, Dock, Pets, Fire Pit

Sunsets and Siestas -Lake Keowee home near Clemson

Pet + Family Friendly 4BR Pool House Near Furman

Pet-friendly, pool, Apt, firepit, 3 min to Furman

Mountain Laurel Retreat

Enchanting 1906 Farmhouse
Weekly house rentals

Walkable 3BD Home Prime location to DT w/ Parking

Sunset Point-Best view on Broadway - HOT TUB!

Lake Living with Amazing Views of Lake Hartwell

Lake house waterfront, 10 min to downtown w Kayaks

Retreat on Lake Hartwell, THE BEST DOCK, Sleeps 8!

Private Waterfront Oasis - Lake Hartwell

Spectacular Lakefront Retreat on the Saluda

Lakehouse Therapy and Clemson Football
Private house rentals

Wildcat's Lair

Industrial Farmhouse Cabin with a Surprising View

aunt helen's house

Relaxing On Riviera

5 minutes to town! Emerald Ferns Cottage

Bobber Bungalow *level lot*fire pit*kayak*canoe

Lake Hartwell Hideaway

Peaceful 4 bedroom Lakehouse with no neighbors
Quick stats about house rentals in Seneca
Total rentals
30 properties
Nightly prices starting at
$40 before taxes and fees
Total number of reviews
1.5K reviews
Family-friendly rentals
20 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with dedicated workspaces
10 properties have a dedicated workspace
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- Black Rock Mountain State Park
- Table Rock State Park
- Tallulah Gorge State Park
- Mountaintop Golf & Lake Club
- Don Carter State Park
- Tugaloo State Park
- Helen Tubing & Waterpark
- Bell Mountain
- Gorges State Park
- Jump Off Rock
- Victoria Bryant State Park
- Anna Ruby Falls
- Wade Hampton Golf Club
- Old Edwards Club
- Ski Sapphire Valley
- Funopolis Family Fun Center
- Discovery Island
- Carl Sandburg Home National Historic Site
- Haas Family Golf
- Victoria Valley Vineyards
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