Seneca vacation rentals

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Top-rated vacation rentals in Seneca

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

Home in Seneca
Cozy Lakefront A-Frame Cabin Lake Hartwell Clemson
The perfect home for lake lovers and college football fans. Located just ~5 minutes away from Clemson and Death Valley, the newly renovated lakefront cottage will be the perfect stay for you, your family, and friends. With an outdoor fire pit, amazing views, boat dock, kayaks, and a modern kitchen, this retreat has all the amenities you're looking for inside and out! Whether you spend your time relaxing at the house, cheering on the Tigers, or fishing the lake, the Hideaway is sure to please.
$205 per night
Cottage in Westminster
Tiny house
BRAND NEW 490 sq ft tiny house/cottage nestled in the woods in a country setting. Complete with a queen bedroom, a twin/day bed and then a queen bed in loft ( comfortably sleeps 4 adults and one child). We are conveniently located 10 miles from I-85 exit 1 on S Hwy 11. 20 minutes from Clemson, 8 minutes from Seneca, and just a short drive to many hiking trails, lakes and parks in the beautiful foothills of the Blue Ridge mountains.
$92 per night
Shipping container in Walhalla
The Valhalla Sky Suite at Hi Saw Gap
Soar above the canopy of Sumter National Forest in this one of a kind container home, located 0.5 miles from Stumphouse Tunnel, Issaqueena Falls, Yellow Branch Falls hiking trail, and the World class Stumphouse Mountain Bike Park. Unwind after a day of exploring the waterfalls and parks of Upstate SC in your private spa in the sky, or cash in every penny of your million dollar view from the balcony bar and deck. All are welcome!
$221 per night

Stay near Seneca's top sights

Photo of Ingles Market
Ingles Market17 locals recommend
Photo of Lake Keowee Marina
Lake Keowee Marina19 locals recommend
Photo of Copper River Grill
Copper River Grill10 locals recommend
Photo of Dienners Kitchen
Dienners Kitchen6 locals recommend
Photo of Time Drive In
Time Drive In7 locals recommend
Photo of Premiere Seneca Cinema 8
Premiere Seneca Cinema 814 locals recommend

Seneca house rentals

Private room in Seneca
The Golden Corner King Room
$55 per night
Home in Seneca
New! Peaceful Lakefront Home on Keowee!
$162 per night
Private room in Seneca
Friendly, comfortable home
$31 per night
Home in Clemson
Adjacent to Dawson Park/1 mile from Clemson Univ
$90 per night
Home in Seneca
South Cove Bungalow Lake Keowee
$124 per night
Private room in Pendleton
Private Suite In Home (Private Entrance)
$65 per night
Home in Seneca
The Marina House, at the edge of Lake Keowee.
$144 per night
Home in Seneca
Clemson Tiger Hideaway
$107 per night
Private room in Seneca
Safe and family oriented neighborhood!
$50 per night
Home in Seneca
RECENTLY UPDATED Lake House 5 miles from Clemson
$169 per night
Home in Seneca
The Clemson Cottage | 3.6mi to Football Stadium
$204 per night
Home in Walhalla
Entire residential home-Walhalla Close to Clemson
$92 per night
  1. Airbnb
  2. United States
  3. South Carolina
  4. Oconee County
  5. Seneca