
Apartment vacation rentals in Santee
Find and book unique apartments on Airbnb
Top-rated apartment rentals in Santee
Guests agree: these apartments are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santee apartment rentals
Weekly apartment rentals

Charming bungalow near beaches/downtown/Shem Creek
Collen's place is easy to find, in a great location, and so close to many restaurants and attractions. It is also very clean, charming, peaceful and inviting. We thought it was worth the money and would come again!

A Charming Charleston Apt Off King St
We had a great trip to Charleston, SC. Such a walkable location. Made it so easy to have a terrific time. We went to Shem Creek for the day, so close. Perfect mini vaca spot, hope to go back again.

Ground Floor Apartment with Exclusive Courtyard
We LOVED Ashley’s place! Perfect for a girls weekend away with so much to do just outside the place! Walkable to everything including amazing restaurants, shopping, and rooftop bars! Would definitely stay here again next time we come to Charleston ☺️

Park Circle - Walk Anywhere, Pets Welcome, Yard!
we always try to have nice rentals wherever we travel. The attention to details here was exceptional. I said I thought it was the nicest Airbnb we've ever stayed. Very clean and well decorated. loved the coffee maker and the basket of k cups already waiting. Everything felt like a hotel suite but better..IF YOU ARE TRAVELING WITH A DOG. They're has never been such a perfect place for someone traveling with there dog. The backyard is perfect for them and theirs a dogpark 5 minutes away. Theirs also a little park in front of the apartment. I've never seen a neighborhood with so many people out walking their dogs. This has to be the most pet friendly inviting place on earth lol I took our dog to the dogpark multiple times because it was so close to the rental. Down town Charleston wasnt far away either we did plenty of sight seeing. The Aquarium was maybe 20 minutes away? perfect location and a perfect rental! A plus plus plus...

Luxurious, Spacious & Historic- 5 Min Walk to King
Absolutely loved this spot! Waking up in the super comfy bed looking out the window to see palm trees and gas lamps was a dream. A great location. Super walkable and always felt safe! The smells from Southbound restaurant were amazing and although we did not get a chance to eat there this time we will definitely be back! Holey city bagels for breakfast and coffee was our morning routine and they had allergy options which was incredible! Overall there was great communication, everything was clean and super cozy! The robes were also an amazing touch, because lets be real who doesn't love a nice robe on vacation! Will definitely stay again and look forward to it!

Home Away from Home! 1 Br & 1 Bath Apt. with Porch
This was our first Airbnb stay and couldn't be more pleased with our stay here. Everything from beginning to end was fantastic. The place was nice, clean and had everything we needed for our stay. The privacy fenced in back yard was a bonus since we had our lil doggie traveling with us! This will be our go to when back in town visiting family!

Mt. Pleasant Charming Suite near Beach, Charleston
Alex and Karen were wonderful hosts! Very responsive, kind, and knowledgeable about the area. They even provide a list of recommended restaurants in the area. Old village in Mount Pleasant is a great central place to stay. Close to beaches and also close to downtown Charleston. Would stay again!

Modern Downtown Gem w/Backyard-3 Blocks to King St
We had a fantastic stay at this Airbnb in Charleston! The location was absolutely perfect—close to everything we wanted to see and do, yet tucked away enough to feel peaceful and relaxing. The home itself was spotless, beautifully decorated, and incredibly cozy. You can tell a lot of care and attention has gone into creating a welcoming space. We felt right at home the moment we walked in. Would absolutely stay here again and highly recommend it to anyone visiting Charleston!
Private apartment rentals

Perfect Location - Downtown Charleston - 1BR/1BA
An easy walk away from King Street, in a great neighborhood with plenty of access to groceries, coffee, etc. Highly recommend hanging out on the beautiful wraparound porch...so beautiful in fact that I proposed there after our first day in Charleston. She said yes! This place will always be so special to us.

Ophir Oasis Unit #1
Not my first time here, great place, frank is a great host. On top of everything, answers whenever you need him. See you next time, Frank.

Historic City Charm | Private Modern Luxe
Perfect spot for an amazing stay in Charleston. The location is ideal, great AC, along with comfy mattresses and pillows. The kitchen was equipped with everything you need…a real bonus to find Tim provided wine and coffee for his guests. The home is close to everything…walk on the battery, around the lake, through the historical neighborhoods not to mention shopping and restaurants! If you want to beach it, free parking outside your door. Highly recommend! It is absolutely perfect:-) We will definitely be back.

Cozy Bungalow on the 18th hole
It was comfortable and cute. It was easy to find and the directions made getting in a breeze. There were good restaurants nearby, we particularly liked Millers All Day. With a car, it was easy to get everywhere we went. We’d definitely stay there again. As has been mentioned, it’s on a pretty busy, but low speed road. There was traffic noise, but not enough to bother us. Turning left out of the driveway could be challenging because it’s so close to a stoplight, but people were generally nice and let us in.

Trendy Downtown Upper King Area~Rutledge Retreat A
Such an affordable and cute spot!! It was exactly what we were looking for! Came to town for a wedding and needed something clean and close to King Street. Perfect little getaway for a couple!! Highly recommend

The Nora
This was such a great find! Very clean and tidy studio with full-sized bathroom and kitchenette. I was surprised to find that it had everything we needed for cooking meals and spending a few days away while not feeling overcrowded or cluttered. This really is perfect for a getaway for 1-2 people. We were close to everything and spent a lot of time exploring Charleston and the surrounding areas. Our host was great, too! He was nice, thoughtful, and responsive. Definitely would stay again!

Spacious 3BR Apartment (Pool, Wi-Fi, Kitchen)
This is a nice, large , 3 bedroom apartment on the ground floor of this complex. It was extremely clean, quiet and in a good location with a Publix and several restaurants close by. We were there for my granddaughter’s basketball tournament and the drive to the athletic center was 18 minutes. The hosts were really responsive and friendly. I would stay there again.

Spacious 3BR- Pool- Gym- 1st Floor
Nice and clean, simple check in/out process, and overall a great experience. The pool and gym are great amenities (we actually wish we’d stayed an extra day just to have a pool day). The area isn’t anything to write home about, but it’s a quick drive to everything we wanted to do. Would definitely come back!
Apartment rentals with a hot tub

Southern decadence 2 min from park circle
The place is really beautiful I love the tub and a plus is a cute doggy next door! I loved the decor and the tv was pretty cool To be honest

Gated Luxury Condo @ The Gates
Great Condo near William Brice Stadium. Easy to get to and secure parking. Had everything I needed for my stay for my son's commencement.

Waterfront Private Hot Tub Fire Pit Dock Fishing A
What a beautiful location! Some of the most stunning sunsets I've ever seen! Great grocery store conveniently located close by! Close to restaurants and shopping!

Private Room ! Style and Comfort in West Ashley
My husband and I had an amazing stay at Alex's place! It's in a quite neighborhood with convenient parking. The apartment was nicely decorated, clean, and had everything we needed. There was plenty of space for the two of us. I particularly liked a walk-in closet. We could put all our bags out of the way. The bedding was comfortable and we had good night rest. Everything was just fine. I would highly recommend this property to anyone looking for a comfortable and convenient stay.

Luxe Lakefront Apartment w/ Shared Pool & Dock!
Jeff and Elizabeth are great hosts! They made us feel incredibly welcome from the moment we walked through the door. They made fresh bread and had it waiting for us, along with an invite to a community event. Elizabeth and Jeff are lovely people and made us feel right at home. My teenage son told me to definitely book with them again next time I’m in town.

Spacious 3 BR Resort Apt Great for Groups in CHS
This Air BnB was exactly what we were looking for! The community was adorable, especially with the coffee shop right down the road. The beds were super comfy which is always a plus when staying at an Air BnB. Only thing was a bit inconvenient was that there were no hangers in any closets to hang up any clothes. Other than that, the perfect stay!

The perfect family space in Elgin. Townhouse
Great space near Columbia. Perfect amount of space for my family while we were in town.

New Studio Apt. in Hemingway
This was a very beautiful and cozy space. The property was absolutely gorgeous and peaceful. The hostess was very responsive and friendly. I will definitely book again on my next visit to South Carolina.
Quick stats about apartment rentals in Santee
Total rentals
10 properties
Nightly prices starting at
$190 before taxes and fees
Family-friendly rentals
10 properties are a good fit for families
Rentals with a pool
10 properties have a pool
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Wifi availability
10 properties include access to wifi
Destinations to explore
- Hilton Head Island Vacation rentals
- Augusta Vacation rentals
- Columbia Vacation rentals
- Folly Beach Vacation rentals
- Mount Pleasant Vacation rentals
- Isle of Palms Vacation rentals
- Atlanta Vacation rentals
- Gatlinburg Vacation rentals
- Charleston Vacation rentals
- Western North Carolina Vacation rentals
- Myrtle Beach Vacation rentals
- Charlotte Vacation rentals
- Cabins United States
- Treehouses United States
- Glamping United States
- Tiny Houses United States
- Beach Houses United States
- Campers and RVs United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes