Santee vacation rentals

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Popular amenities for Santee vacation rentals

Stay near Santee's top sights

Clark's Restaurant11 locals recommend
Captains Quarters Seafood and Steak11 locals recommend
Lonestar BBQ & Mercantile10 locals recommend
Armando’s Mexican Restaurant10 locals recommend
Lake Marion Golf Course7 locals recommend
Food Lion7 locals recommend

Santee house rentals

Superhost
Home in Columbia
4.68 out of 5 average rating, 22 reviews

Cozy Col - home near downtown/ Fort Jackson/

BryanRating, 5 stars6 months ago
Host was very reachable. Place was clean and maintained. Family of 4 with our pets fit and didn’t feel cramped. Worth the stay and easy to get to anywhere locally.
Top guest favorite
A cozy living area features a light-colored sectional sofa adorned with colorful throw pillows, accompanied by two wooden chairs. A vibrant red patterned rug covers the floor, while a wooden sideboard and a large flat-screen TV are positioned along the wall.
Home in Sumter
5 out of 5 average rating, 69 reviews

The Oasis

ErinRating, 5 stars2 weeks ago
We stayed while visiting family in the area with our two boys. The space overall was perfect for our family of 4. It was close to all the places we were visiting and the hosts also provided great recommendations for restaurants. The neighborhood was very quiet as well! Only downside would be that the front room did not have black out curtains, otherwise a wonderful stay.
Top guest favorite
A spacious patio area features a round dining table surrounded by metal chairs. Nearby, a swing chair and a lawn are visible, framed by trees with hanging Spanish moss. A shed is situated in the background, complementing the tranquil outdoor setting.
Home in Goose Creek
4.98 out of 5 average rating, 100 reviews

Charming Ranch House

DonnaRating, 5 stars1 week ago
The house is in a very nice location in a quiet neighborhood. It’s very well maintained and squeaky clean. The location is very good because you’re not far away from anything. We stayed at the house on a work trip so I didn’t cook much however I did fix my breakfast & the kitchen was equipped with everything I needed. Our host was very responsive and we will definitely stay there again. Highly recommended.
Superhost
A cozy living room is presented with red walls and hardwood flooring. Two comfortable sofas and a coffee table with a decorative surface are arranged, complemented by a floor lamp and an entertainment center. Natural light flows through multiple windows, enhancing the welcoming ambiance.
Home in Cayce
4.77 out of 5 average rating, 151 reviews

3/1.5 house in Cayce Close to USC, Ft Jackson, CAE

JoseRating, 5 stars3 weeks ago
Joseph place was really comfortable and cozy. Joseph is a great host very responsive and accommodating. House has everything you need. Thanks Joseph!
Top guest favorite
A contemporary living room features a blend of textures with an orange sofa and two navy chairs. A television sits on a low wooden stand, while light floods the space through sheer curtains. Decorative wall art and a rug add visual interest to the area.
Home in Florence
4.96 out of 5 average rating, 24 reviews

2b/1.5bath brand NEW townhouse Closed to MUSC

ChristopherRating, 5 stars4 days ago
This is the 2nd time I have stayed at this location in Florence. The place is very clean, comfortable beds, clean bathroom, and very easy to get into. The location was perfect for our needs, close to stores, food, and Francis Marion University. Wempy is a great host and very repsonsive. He answers mail within minutes and is always helpful. I would stay here again for sure. Thank you for a great stay!
Top guest favorite
A spacious living area features a high ceiling, two lamps providing warm lighting, and a comfortable seating arrangement that includes a large sofa and armchairs. A coffee table occupies the center, adorned with decorative items. Natural light enters through a nearby window.
Home in Sumter
4.95 out of 5 average rating, 43 reviews

LODGING @ OLD TOWNE LANDING SUITE A

DemitriusRating, 5 stars2 weeks ago
Very nice house, quiet neighborhood. Also military friendly, would definitely stay again!!
Guest favorite
A single-story brick home is featured, showcasing large blue shutters on the front windows. A green lawn leads to a covered porch with steps. An attached garage is visible on the right, with vehicles parked inside.
Home in Dalzell
4.86 out of 5 average rating, 21 reviews

Beautiful Home Away from Home Near Shaw AFB

FranciscoRating, 5 stars8 months ago
Great location, we had no problems at all with this beautiful home and host!
Superhost
A stylish living area features a tan leather sofa adorned with decorative pillows, set against a lush green patterned wallpaper. A wooden coffee table sits atop an intricate area rug, complemented by a sleek side table and indoor plants adding a touch of nature.
Home in West Columbia
4.83 out of 5 average rating, 23 reviews

Unit B: Whimsical 2-bedroom Home w/ Fast WiFi

RodRating, 5 stars6 days ago
5 Stars I stayed at Rayne and Palmer’s place for a full month, and the experience was excellent from start to finish. The space was clean, comfortable, and exactly as described. It felt like a true home away from home. Rayne was incredibly communicative and thoughtful throughout the stay—always available when needed but never intrusive. Check-in was smooth, the neighborhood was quiet and peaceful, and all the essentials were provided. I really appreciated the attention to detail and how everything was maintained—from trash and recycling to pest control and lawn care. It’s clear that they care about their guests having a great experience. If you’re considering a longer-term stay, I highly recommend this property. Thanks again for hosting us so graciously!

Other great vacation rentals in Santee

Guest favorite
The kitchen features gray cabinetry complemented by light-colored countertops. A sink is positioned between the countertop and a white oven. A refrigerator and a microwave are also visible. The floor is laid with tiled patterns, and a small mat is placed in front of the sink.
Home in Sumter
4.93 out of 5 average rating, 101 reviews

Welcome! a relaxing retreat...home away from home

PreciousRating, 5 stars4 days ago
Patricia home was lovely for my family and I. Really enjoyed the yard space and amenities provided
Top guest favorite
A scenic view from the balcony shows a tranquil lake and adjacent pool area. Palm trees and lush landscaping frame the space, creating a relaxing outdoor environment. The calm water reflects the sky, enhancing the serene lakeside atmosphere of the property.
Condo in Santee
4.96 out of 5 average rating, 145 reviews

Beautiful lakefront condo overlooking Lake Marion.

KaseyRating, 5 stars6 days ago
Our stay was wonderful. Billie was always super responsive and accommodating. The place was exactly as posted. Plenty of room for me, my parents, and my two small kiddos. The location is great. Right on the lake. We caught some fish off the fishing dock. The walking bridge is super cool too. The pool was nice and clean. Would come back and stay here again.
Top guest favorite
The image showcases a scenic view of a calm lake from a deck area. Several outdoor chairs are positioned along a railing, with lush green grass and trees framing the water. A private dock is visible, extending into the lake.
Home in Summerton
4.99 out of 5 average rating, 106 reviews

Cheerful 3 bedroom home on the lake

HollyRating, 5 stars4 weeks ago
Absolutely beautiful! The place was clean and inviting. The hosts had provided everything you could possibly imagine, even personal items if you forgot anything. There was so much to do for entertainment both inside and outside the home. We had a great time!
Top guest favorite
An electric fireplace is framed by a black surround, featuring glowing blue and orange flames. A decorative log piece lies within the firebox, and a sign reading 'HOME SWEET HOME' rests below, adding a touch of warmth to the living area.
Condo in North Charleston
4.96 out of 5 average rating, 51 reviews

2 Beautiful Master Suites

EthelRating, 5 stars1 week ago
Kathy’s place was very nice and comfortable. Close to Brecks where we got a 30 oz steak for $32.99 was not a fancy place, but it was worth it and the steak was awesome. Another place we ate on the way out was in Somerville. Shuckin shack oyster bar. They had a great menu low price for the best oysters, clams and mussels. Steamed or raw also a great fried cod sandwich. I am sure everything there was awesome!! Oh good Bloody Mary too! The proximity of Karen’s place to a lot of things to do was nice. She also left us much appreciated wine and a gift. Thank you Kathy for a great stay!
Top guest favorite
The image captures a serene lakefront view featuring a grassy area that leads to a private dock. Two kayaks rest on the shore, while a pedal boat is visible in the foreground. Lush greenery and homes are seen lining the opposite shore.
Home in Lexington County
5 out of 5 average rating, 19 reviews

Lazy Days - Priv Dock,Kayaks,Arcades,Pet Friendly

MattRating, 5 stars3 weeks ago
Had a wonderful stay at this property! House was amazing! Very clean and great views on the lake. Nice screened in porch which was great to hang out on. Kitchen, living room, and bedrooms were all very comfortable. Scott and Lauren were both extremely helpful and checked in with us throughout the stay to make sure we had everything we needed. 5/5 would recommend and would stay again if in the area!
Top guest favorite
A spacious deck is highlighted by lounging chairs and a large dining table, offering views of the serene lake waters. Two trees frame the area, complementing the outdoor relaxation space. A dock is visible in the distance, contributing to the tranquil waterfront setting.
Home in Summerton
5 out of 5 average rating, 22 reviews

The Heron Lake House

SamanthaRating, 5 stars2 weeks ago
The perfect stay! Beautiful lake, clean and gorgeous house, quiet neighborhood and amazing bang for your buck. We've stayed at a dozen Air B&B's and this was top 3! Plenty of space for our family of 5 (though could have EASILY fit another 3-5 guests). Never felt like we were falling over one another. Great fishing location (though we only caught one fish, haha), calm waters and breathtaking sunrise/sets. About an hour drive from the beach at Charleston (highly suggest Folly Beach). Morgan was responsive when we had questions and was always super kind.
Guest favorite
A view of several homes along the shoreline, surrounded by trees, is captured from the water. The calm surface of the lake reflects the clear blue sky and lush greenery. Various docks and boats are visible near the water's edge.
Home in Chapin
4.88 out of 5 average rating, 34 reviews

Summerset The Heart of Lake Murray

StaceyRating, 5 stars8 months ago
We had a great weekend at this lovely lake house. Multiple outdoor areas to enjoy the water and the view! Loved the property and all it had to offer. Curt was a great host, as well!
Superhost
The exterior of a two-story house is displayed, featuring light siding and dark shutters. A two-car garage is visible, along with a manicured lawn and landscaping. The driveway is spacious, leading to the entrance, while additional homes are seen in the background.
Home in Summerville
4.69 out of 5 average rating, 103 reviews

Low Country Living by Low Country BNB

ErinRating, 5 stars4 weeks ago
I can't say enough good things about Iris and this place! They were extremely kind and helpful. Would recommend staying with them anytime you are in the area! I know we will be!

Quick stats about vacation rentals in Santee

  • Total rentals

    20 properties

  • Nightly prices starting at

    $100 before taxes and fees

  • Total number of reviews

    170 reviews

  • Family-friendly rentals

    20 properties are a good fit for families

  • Rentals with a pool

    20 properties have a pool

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

Frequently Asked Questions

  • Are there vacation rentals with a dedicated workspace in Santee?

    Yes! Work meets play with ease at over 10 vacation rentals in Santee featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • How much does it cost to stay in apartment rentals in Santee?

    Experience the best of Santee with our apartment rentals, starting at about $190 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Do apartment rentals in Santee have a gym?

    Absolutely! We offer over 10 apartment rentals with a gym in Santee. Enjoy a tailored experience with all the comforts you desire.

  • Do apartment rentals in Santee have wifi?

    Absolutely! We offer over 10 apartment rentals with wifi in Santee. Enjoy a tailored experience with all the comforts you desire.

  • Are there Santee apartment rentals on Airbnb with pools?

    Yes! Dive into the perfect getaway at one of over 10 apartment rentals with pools in Santee, available on Airbnb. Make a splash and soak up the sun in style!

  • Are there family-friendly apartment rentals in Santee?

    Santee has more than 10 family-friendly apartment rentals. Amenities on the property may include high chairs, travel cribs, or strollers.

Destinations to explore