Vacation rentals in Mira Mesa

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Top-rated vacation rentals in Mira Mesa

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Guest suite in Mira Mesa
4.97 out of 5 average rating, 121 reviews

Private Suite w/ full Kitchen, Bath,Washer & Dryer

Newly-built 1 Bed/1 Bath Guest Suite with private entrance, private restroom, new air conditioning unit, new full-size kitchen and new washer/dryer inside the unit. It's a centrally-located place near Qualcomm, Sorrento Valley, UCSD, La Jolla beaches, etc...Easy access to I-15 and 805 freeways. Convenient travel to Legoland, SeaWorld, San Diego Zoo, USS Midway Museum,Balboa Park and many other attractions in San Diego. It offers everything you need for a nice stay. Check out our awesome reviews!

Top guest favorite
Home in Mira Mesa
5 out of 5 average rating, 14 reviews

Quiet & Spacious 4b/3b House with backyard

Get a large two-story house to yourself in Mira Mesa, located next to numerous restaurants and shopping plazas on Mira Mesa Blvd. This spacious home includes four bedrooms and three full bathrooms, two living rooms, a backyard, garage and large driveway for convenient parking. The property provides a quiet and safe environment, ideal for light sleepers, with minimal disturbances from neighbors. A 15 minute drive to Del Mar, La Jolla, Downtown, Convoy Street, the San Diego Zoo, Poway & more.

Top guest favorite
Guesthouse in San Diego
4.98 out of 5 average rating, 51 reviews

Modern & Private Guesthouse in Scripps Ranch

Relax in this beautiful guesthouse with private side yard. Enjoy a fully-equipped kitchen with fridge, oven, dishwasher, cookware and a coffee bar. Dine or work comfortably at a bar-height table with adjustable barstools. The bedroom has a king bed, and there is a convertible recliner/sleeper chair in the living room for a third person to sleep. The bathroom features a walk-in shower and in-unit washer/dryer combo. Parking is free, right in front. One or two pets under 30 pounds are ok.

Top guest favorite
A spacious room is furnished with a plush brown sectional sofa adorned with red accent pillows and an ottoman. A large bed with neutral bedding is positioned nearby, and framed artwork adds subtle elegance to the wall, complemented by soft ceiling lights that enhance the inviting space.
Guest suite in Mira Mesa
4.92 out of 5 average rating, 143 reviews

Stunning Private Entrance 2bd/1ba Suite

Located in the heart of San Diego, guests are a short drive or bus ride to all the local hotspots. Shopping and restaurants are within walking distance. The space itself is large, exquisitely decorated, has a dedicated driveway parking space and its own private entrance in the front of the house. Also available are the washer/dryer for laundry, beach equipment, electric bikes (with signed waiver), cribs/toys/etc. for children. Short drive to SeaWorld, Zoo, Safari Park and beaches.

Guest favorite
Guesthouse in Mira Mesa
4.92 out of 5 average rating, 107 reviews

Pets and family cozy suite with private yard

Welcome to our cozy San Diego Mira Mesa Guesthouse! This private 600 sqft suite offers comfort and convenience for families, friends, and pets. Enjoy a brand-new sofabed added Sep 13th 2025. For those working during their stay, the suite includes a dedicated remote-friendly workspace with fast WiFi and natural light, ideal for video calls or productivity on the go. With quick access to Freeway 15, you’re just 15–20 minutes from beaches, downtown, and San Diego’s top attractions.

Top guest favorite
A wooden play structure featuring a slide and windows is placed on mulch in the backyard. A green sandbox sits nearby, under a shaded tree. The fenced area provides a safe and inviting space for outdoor play.
Home in Mira Mesa
4.94 out of 5 average rating, 332 reviews

Contemporary Family-Friendly Home in SD with EV&AC

Welcome to San Diego, the city of sun and fun. This newly-renovated, spacious home has 3 beds and 2 baths with central AC, and is conveniently located in the center of San Diego with easy access to freeways 5, 805 and 15. It's close to many attractions -Legoland, Sea World, San Diego Zoo, Balboa Park, and beautiful beaches. The neighborhood has a variety of restaurants, cafes, movie theater, shopping center, and grocery stores. Just a few minutes from Sorrento Valley and UCSD.

Top guest favorite
The living room features a spacious layout with vaulted ceilings, two comfortable sofas, and a coffee table. A decorative mirror hangs above a modern fireplace, while a wine and beverage fridge adds convenience. Natural light enters through the window, enhancing the inviting ambiance.
Home in Mira Mesa
4.96 out of 5 average rating, 106 reviews

Bright Cozy 3b/2b with nice backyard & BBQ

Our family-friendly, single story home is centrally located in a quiet neighborhood of Mira Mesa. Less than 1 mile to restaurants, grocery stores, banks, shopping centers while just a short drive to beaches, hikes, parks, local breweries & San Diego attractions. The entire home offers a spacious living room, a separate fully equipped kitchen and dining up to 8, comfy beddings, memory foam mattresses in all rooms & turf backyard with patio furniture for a comfy, relaxed stay.

Top guest favorite
A spacious bedroom features a black metal bed frame with patterned bedding. A small bedside table is positioned beside the bed. Natural light fills the room through a large window, which is adorned with light-colored curtains that complement the neutral walls.
Guesthouse in Mira Mesa
4.92 out of 5 average rating, 79 reviews

Gated Detached Large House Convenient/Quiet

The spacious detached casita/guest house comes with private entrance and a backyard. It has a large bedroom, walk-in closet, full bathroom, living dinning, and kitchen. The kitchen has new sink, stove/oven, refrigerators, essential cookware, utensils, and tableware. The house has a queen size bed that can sleep two adults, a brand new sofa sleeper bed and a queen size air mattress for additional guests. Guest may use the new LG washer/dryer combo unit.

Top guest favorite
A single-story ranch home is set amidst a landscaped front yard featuring vibrant green grass and white gravel accents. A large tree provides shade by the entrance, while a well-maintained driveway leads to a garage. Clear skies add to the welcoming exterior ambiance.
Home in Mira Mesa
4.98 out of 5 average rating, 58 reviews

Charming Family 3BR w/ Game Room

Experience San Diego living in this welcoming 3-bed, 2-bath Mira Mesa home. Perfect for families with a fun game room for entertainment and a spacious backyard featuring covered patio seating and grill for outdoor dining. Minutes from scenic hiking trails, family-friendly parks, and beautiful beaches. Easy access to diverse local restaurants. Your ideal Southern California base with space for both lively gatherings and relaxing downtime.

Guest favorite
A kitchenette area is visible, featuring a small dining table with two chairs and a leather sofa nearby. Storage cabinets and a full-size refrigerator are included. A coffee maker, sink, and various kitchenware are arranged on the countertop, with decorative art hanging on the wall.
Guest suite in Mira Mesa
4.87 out of 5 average rating, 196 reviews

STUDIO 56

Entire Private Studio Suite. The entire suite is brand new and updated with 1 queen bed, 1 double bed, and 1 full bath. Quiet midtown of Mira Mesa central drive in San Diego. Studio fully equipped with 2 beds, a leather sofa, working desk, kitchenette meant for light food warm, full size refrigerator, single sink meant for light cup and dish wash All shops, restaurants, a cinema within minus drive about 2 miles away.

Guest favorite
A cozy sleeping area features a spacious bed with a blue blanket and decorative pillows. Soft lighting is provided by two bedside lamps on dark wooden nightstands. A bright piece of wall art hangs above the bed, and a clothing rack is positioned nearby.
Home in Mira Mesa
4.84 out of 5 average rating, 70 reviews

Charming & Spotless Studio with Own Entry

Entire Private Studio Suite. Brand new updated entire suite with 1 Queen Bed & 1 Full bathroom. Ideal for couples, solo adventurers, and business travelers. Just minutes from central of shopping and food like Asian restaurants, markets as well as 24h stores, Edward Cinema, etc... Less than 20 mins to Balboa Park, La Jolla Shores Park, Solana Beach, Moonlight Beach, San Diego Zoo, San Diego Sea World.

Guest favorite
A modern living area features a blue upholstered sofa paired with two wooden armchairs. A wooden coffee table sits in front, complemented by a decorative rug. A plant adds a touch of greenery, while artwork adorns the wall. A dining area is visible in the background.
Home in Mira Mesa
5 out of 5 average rating, 25 reviews

Urban Oasis - Just Remodeled

**Brand New Listing** Located in the heart of Mira Mesa and just minutes from the 15 Freeway, this beautifully remodeled home offers the perfect combination of style, comfort, and convenience. Whether you're visiting for business, pleasure, or a bit of both, you'll love the thoughtful upgrades and luxurious touches throughout. The home offers plenty of parking, in a safe neighborhood.

Popular amenities for Mira Mesa vacation rentals

When is the best time to visit Mira Mesa?

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Avg. price$93$93$102$101$104$116$113$106$98$79$93$94
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Quick stats about vacation rentals in Mira Mesa

  • Total vacation rentals

    Explore 270 vacation rentals in Mira Mesa

  • Nightly prices starting at

    Mira Mesa vacation rentals start at $20 per night before taxes and fees

  • Verified guest reviews

    Over 12,970 verified reviews to help you choose

  • Family-friendly vacation rentals

    100 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 50 rentals that welcome pets

  • Vacation rentals with a pool

    60 properties feature pools

  • Rentals with dedicated workspaces

    190 properties have a dedicated workspace

  • Wi-Fi availability

    270 of Mira Mesa vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mira Mesa rentals

  • 4.8 Average rating

    Mira Mesa stays are highly rated by guests—averaging 4.8 out of 5!

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