Guesthouse vacation rentals in Jefferson County

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Jefferson County guesthouse rentals

Family-friendly guest house rentals

Guest favorite
A modern living area features a pink sectional sofa adorned with blue and orange throw pillows. A decorative wall art piece and a round mirror provide a vibrant focal point against a chevron-patterned accent wall. Soft lighting emanates from a stylish light fixture overhead.
Guesthouse in Louisville
4.95 out of 5 average rating, 66 reviews

Retro Chic Private Getaway in the Highlands.

WilliamRating, 5 stars1 month ago
We had a great stay; the place was nicely decorated but not over the top, the amenities were useful and location was on a quiet street in a nice neighbourhood and in walking distance of Bardstown Road. Stacey was very friendly and helpful!
Guest favorite
A compact kitchenette features stylish elements such as a patterned backsplash and a window allowing natural light. Two green bar stools are positioned at the counter, while a small sink and microwave are visible. A potted plant adds a touch of greenery to the space.
Guesthouse in Louisville
4.94 out of 5 average rating, 77 reviews

Yoga Barn with 90’s Loft Bedroom

FeliciaRating, 5 stars2 days ago
This was the perfect location for a peaceful getaway, but close enough to easily enjoy the things Louisville has to offer! I visited with 2 dogs and the barn was the perfect size for us- complete with a beautiful porch and a fenced yard. Anne was very responsive and accommodating as my plans changed. I would highly recommend this location, and would stay again if passing through Louisville.
Superhost
Guesthouse in Pendleton
4.87 out of 5 average rating, 67 reviews

The Waterfall Place, Suite and Walkout!

CloyRating, 5 stars1 month ago
Such a beautiful home! So calm and peaceful. The waterfall feature and sitting areas are perfect!! The grounds have trails to walk, a playhouse for kids, a pool, and hot tub. It accommodated our large family and we can’t wait to come back and stay again!! We highly recommend this place. 😃
Guest favorite
A white, two-story wall is complemented by a wooden deck featuring a railing. Flower pots are placed at each end of the deck, and large windows are visible on the upper level. A staircase leads from the ground level to the deck.
Guesthouse in Louisville
4.9 out of 5 average rating, 134 reviews

Cottage Park Carriage House. Rest w/Hollyhock

StewartRating, 5 stars2 weeks ago
My mom has stayed at this location multiple times because she loves it. They always treat her with the utmost respect and the space itself is immaculate and comfortable. highly recommend!
Guest favorite
A view from the guest house porch reveals a serene pasture with several horses grazing. A black wooden fence encircles the expansive, green field under a clear blue sky, creating a peaceful rural atmosphere. The surrounding trees provide a natural backdrop.
Guesthouse in Shepherdsville
4.94 out of 5 average rating, 53 reviews

Bourbon Country/ Derby Guest House

MelanieRating, 5 stars10 months ago
Ramona and Steve were fantastic hosts. They made us feel right at home. Their location is beautiful and peaceful and just good for the soul! If my family and I are ever in the area again we will definitely love to visit again!
Guest favorite
A cozy living area features a spacious sectional sofa facing a television. Natural light filters through the windows, illuminating the dining table adorned with a decorative bowl of assorted items. The kitchen area is visible, enhancing the open layout of the space.
Guesthouse in Louisville
4.92 out of 5 average rating, 299 reviews

Charming Carriage House with 2 private baths.

LoriRating, 5 stars3 weeks ago
Stacy’s place is located a beautiful neighborhood. I enjoyed morning walks and felt very safe staying there. Her place was exactly as described and suited my daughter and i very well.

Guest house rentals with a patio

An open living area is highlighted by vaulted wood ceilings and large windows that allow natural light to fill the space. A brown leather sofa is complemented by a matching chair, while a textured area rug lays beneath. A sleek kitchen bar is visible in the background.
Guesthouse in Charlestown
4 out of 5 average rating, 5 reviews

Watson Mansion Carriage House

KarlaRating, 5 stars3 weeks ago
I’m originally from this area so I’m partial to it. Where the house was located is safe and close to the square where you can sometimes find live music, restaurants, and other seasonal activities. The host was responsive and without asking, turned the lights on since our arrival was going to be late. The place was exactly as described. Not really knowing what to expect, we were planning to use the pull out bed in the living room, however it’s about a 3 inch folded memory foam on top of solid wood so for anyone with a questionable back you might want to bring an air mattress or something else. We definitely plan to stay here again when we are back in the area.
A spacious sleeping area features a blue bedding set on a large bed, complemented by decorative pillows. A cozy green couch sits nearby, adorned with patterned cushions. Natural light flows in through a window, illuminating the room's warm wood flooring and neutral walls.
Guesthouse in Louisville
4.84 out of 5 average rating, 25 reviews

Cozy Carriage House - Game Room -Sleeps 4!

TonyRating, 5 stars4 weeks ago
This was the place I needed for the weekend. It was very Peaceful and the place was so nice, clean and relaxing! Maria was so nice and very easy to communicate with. I would recommend this place to everyone.
Top guest favorite
A green lawn surrounds a fenced-in area featuring a heated pool, with lush banana plants adding to the tropical feel. The house, painted in muted tones, is visible in the background, with outdoor seating areas nearby, inviting relaxation.
Guesthouse in Bloomfield
5 out of 5 average rating, 9 reviews

Country 1 bedroom guesthouse with heated pool

EmilyRating, 5 stars8 months ago
Valerie, Jim, and Dixie were absolutely fantastic! I can’t say enough good things about them and their lovely home. I felt so welcomed and had the best time. Valerie was especially personable and me feel comfortable and right at home. She gave me a few lifts to Bardstown, which were beyond helpful and shared some great recommendations! The pool and fishing pond are delightful, the hammock is amazing, and the views are beautiful. Angel’s Rest was pure paradise and I would 100% stay again!!
A spacious living area features a combination of seating options, including a couch and armchair with decorative pillows. A coffee table sits in the center, while the open layout leads to a dining area and fully equipped kitchen in the background.
Guesthouse in Crestwood
5 out of 5 average rating, 4 reviews

Lots of cozy and fun space!

MarcRating, 5 stars8 months ago
Stephanie was incredible! She was super kind, welcoming, and accommodating, especially when we had an issue with another place we had planned on staying. She let us check in early and let us add another night last minute. The space was lovely! Very clean and homey. Plenty to do indoors, had all the amenities listed, and the surrounding area was beautiful. Whole heartedly recommend staying here! Stephanie is awesome and the space is awesome!
Top guest favorite
A bright living area features a light blue couch and a black futon, providing additional seating options. A wooden coffee table is centrally placed on a patterned rug. Natural light enters through a glass door leading to the outside, with minimalistic decor enhancing the space.
Guesthouse in Jeffersonville
4.9 out of 5 average rating, 69 reviews

Modern Guesthouse overlooking Ohio River

EvanRating, 5 stars2 months ago
Great little spot for 2-3 guest!
Guest favorite
A studio space is shown with warm wood-like flooring, featuring a full bed dressed in a green blanket. An air conditioning unit is positioned near a window, and a flat-screen TV is mounted on the wall opposite the bed. A floor lamp and a small table complete the room.
Guesthouse in Louisville
4.95 out of 5 average rating, 20 reviews

The tiny Walnut in Beechmont

JoshRating, 5 stars1 month ago
Very convenient to the Expo Center... More comfortable than a chain hotel room. Would certainly use again if the price made sense.
Guest favorite
An open concept living area presents a spacious layout with a red leather sofa and two black chairs surrounding a circular coffee table. A large Smart TV is mounted on the wall, and the area leads to a fully equipped kitchen, while natural light fills the space.
Guesthouse in Louisville
4.91 out of 5 average rating, 85 reviews

Chic Derby stay minutes from Churchill Downs!

AprilRating, 5 stars3 weeks ago
Apartment was in a great location for my son’s Archery tournament at the Kentucky Expo Center. It was also close to the Zoo, Kentucky Kingdom and other attractions. The house was clean and easy to access.
A vibrant mural of horse racing creates a dynamic focal point on the wall of the cozy sleeping area. A spacious bed with blue bedding sits opposite a wall-mounted television, complemented by a small table on one side, enhancing the room's charm.
Guesthouse in Louisville
4.65 out of 5 average rating, 17 reviews

Cozy & fun Studio Near Churchill Downs/Fairgrounds

IvanRating, 5 stars1 day ago
Thank you for a great stay! It was quiet and relaxing. The outside nook was perfect to relax in after my daughter’s volleyball tournament. Location was great about 15 minutes from the Expo Center.

Guest house rentals with a washer and dryer

Guest favorite
A modern living area features a comfortable gray sectional sofa and a sleek lamp beside a large window. A wall-mounted TV is visible across from a stylish marble dining table surrounded by beige chairs. Natural light enhances the space.
Guesthouse in Louisville
4.98 out of 5 average rating, 87 reviews

Highlands Carriage House - Deer Park

RichardRating, 5 stars1 month ago
Kellie was very helpful , providing simple yet detailed instructions for check in well ahead of time. We booked only a week out, yet we got everything we need quickly. Kellie provided some local suggestions for food and places to visit. The space was nice, cozy yet spacious. Very nice bathroom and kitchen. Having our own parking spot was great! And the location was wonderful. Walkable neighborhood with plenty to do and see. An abundance of coffee shops and restaurants only a quick walk away. The place was also very reasonably priced. We'll be back.
An organized kitchen cabinet displays a variety of dishware, including plates, mugs, and decorative storage containers. Below, a coffee maker is positioned next to a bag of coffee, with a textured backsplash adding visual interest to the space.
Guesthouse in Louisville

Modern Hideaway in Historic Butchertown

MichaelRating, 5 stars5 months ago
Kay & Bruce are amazing hosts and I couldn't have asked for a better stay. Sarah was so helpful in the process as well and both were very responsive and punctual. Lovely place and two amazing people to stay with. I will definitely be looking to stay with them again in the coming months visiting back to Louisville. Amazing stay all around!! Went truly above and beyond.
Guest favorite
A row of local shops lines a charming street. The storefronts feature a variety of styles, including a red bookstore with large windows and signage. Street furniture and lampposts add to the inviting atmosphere of the neighborhood.
Guesthouse in Louisville
4.94 out of 5 average rating, 113 reviews

Carriage House - Crescent Hill (Frankfort Avenue)

DeborahRating, 5 stars1 month ago
Frankfort Ave is a terrific location as it is easily walkable to anything you might want. This was also a minutes’ walk to our friend’s home, so absolutely perfect for us as we were there for a celebration. The accommodations were lovely although we did not fully enjoy them as it was basically a place to sleep. This is definitely a go to place we would use again and I highly recommend it. The only suggestion would be to bring a sleep mask as there is a lot of light intrusion by the street lights.
Top guest favorite
A modern guesthouse exterior is framed by lush trees, showcasing a blend of reclaimed wood. Stairs lead to a welcoming entrance, complemented by large windows that provide natural light. The building features a two-car garage below, with a clean concrete driveway.
Guesthouse in Louisville
5 out of 5 average rating, 58 reviews

New custom guesthouse | Free parking | Sleeps 4

CaronRating, 5 stars3 weeks ago
This is our 2nd time staying here. Very clean and welcoming. Great location for walking to coffee shops and restaurants and so easy to get around Louisville. Great for our home away from home !
Top guest favorite
A close-up view of a crackling fire pit is presented, with logs burning brightly. Flames in various shades of orange and yellow dance above the red-hot embers, creating a warm glow in the surrounding area. The texture of the charred wood is visible.
Private room in Prospect
5 out of 5 average rating, 11 reviews

Lewis & Clark Trail Guest Suite

RobertRating, 5 stars3 months ago
If I could i’d give Deborah more than 5 ⭐️ She was an amazing host and took extra time to set the room up specially for Valentine’s day. She went out of her way to make our stay the best experience we have had on AirBnb. She recommended lots of restaurants and the one we decided to go to might have had the best seafood i’ve ever had. She also sent me many trails where I could run at and was super informative on everything she recommended! The place was beautiful and it felt like a home and this is definitely some place i’d love to come back to! Thanks again Deborah!
A modern kitchen is equipped with stainless steel appliances, including a refrigerator and a sink. White cabinets provide ample storage space. A doorway leads to a laundry area, while natural light fills the room through a nearby window, illuminating the countertops and flooring.
Guesthouse in Louisville

Private, Detached, Cottage House

DavidRating, 5 stars27 months ago
Emily was very responsive and helpful! Nice and peaceful place for me to stay while in town for a class. Would definitely recommend
Top guest favorite
The spacious living area features large, historic arched windows that allow natural light to fill the room. A comfortable blue sofa is positioned near a circular dining table, complemented by a modern ceiling light fixture and a flat-screen television mounted on the wall.
Guesthouse in Louisville
5 out of 5 average rating, 76 reviews

Lavish church suite with choir loft

CaseyRating, 5 stars1 month ago
This is one of the coolest Airbnbs we’ve ever stayed in! The space looks exactly like the photos, was easy to find, clean, and walkable within the Nulu district. We love a reclaimed building and felt safe in the area, but note that you are in the middle of a vibrant downtown bar district so there is loud car noises throughout the night. The hosts provided a white noise machine, ear plugs, and eye mask which was appreciated. The renovation of the space was very well done and we felt right at home. If you have an EV, note that there’s a hotel garage right around the corner with 8 chargers in it so it’s easy to park there overnight (which was a big factor for us booking here). Would stay here again!
The entrance to the apartment features a light green door with a window, surrounded by a blend of orange siding and lush greenery. A doormat is positioned just in front of the door, while sunlight and shadows play on the surface.
Guesthouse in Louisville
5 out of 5 average rating, 156 reviews

Your Derby Weekend Getaway

JaneRating, 5 stars29 months ago
Stayed here for two months and wish I could've stayed longer! Perfect amount of space to live and work. Very clean, lots of light, stocked with all the essentials, comfortable bed. The location is in walking distance of a few restaurants and entertainment. A quick drive (or bike ride) to the riverfront and NuLu. The small fenced in courtyard was really convenient to let my dog out. Joan was a great host, very friendly and accommodating.

Destinations to explore