Guesthouse vacation rentals in Cameron County

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Cameron County

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Guest favorite
Guesthouse in Harlingen
Peaceful Country Getaway
This private, cozy guest house is next to our home and includes a bedroom, bathroom, full kitchen, and living room. It has a beautiful view of our 2.4 acre property. Feel free to look at our chickens and rooster (don’t touch the electric fence). Amenities include a queen size bed, WiFi, refrigerator, oven, microwave, coffee maker and much more. Valley Baptist Medical Center–12 minutes Valley International Airport-15 minutes Brownsville–30 minutes McAllen–35 minutes South Padre Island–50 minutes
Mar 27 – Apr 3
$63 per night
5.0 out of 5 average rating, 26 reviews
Guest favorite
Guesthouse in Harlingen
Private Guest Casita Near Downtown Harlingen
A private, cozy, and clean garden Guest Home located in the heart of Harlingen! Close to downtown historic Jackson Street, and just minutes from the airport, you'll soon be immersed in the lush tropical surroundings of the Rio Grande Valley! Wake to the calls of exotic chachalacas, and catch a glimpse of wild parrots. Feel free to pick fresh Ruby Red grapefruits in our backyard grove. Take a dip on nearby South Padre Island, and dine on authentic Mexican cuisine found on nearly every corner!
Mar 20 – 27
$67 per night
4.85 out of 5 average rating, 293 reviews
Guest favorite
Guesthouse in Harlingen
Private Cottage close to Airport
Large ,clean, bright space for work or leisure . Desk and chair , Wi-Fi, cable TV . Queen bed , bedside tables and lamps, clothes rack , iron and ironing board . Day bed to relax or accommodate another person. Kitchenette , prep area , full fridge , gas stove . microwave , Keurig, and cooking utensils . Private bathroom , with walk in shower . Private outdoor sitting area, yard enclosed. Outdoor gas grill . Discounts available for weekly and monthly rates . Dog friendly ,no cats.
Aug 2 – 9
$55 per night
4.97 out of 5 average rating, 501 reviews

Popular amenities for Cameron County guesthouse rentals

Family-friendly guest house rentals

Guest favorite
Guesthouse in Brownsville
EFICIENCY WITH 2 QUEEN AND KICHENET
Jul 14 – 21
$51 per night
4.77 out of 5 average rating, 152 reviews
Guest favorite
Guesthouse in South Padre Island
Tropical Casita-Grounds w/Pool &Hot Tub
Nov 9 – 16
$135 per night
4.81 out of 5 average rating, 129 reviews
Guest favorite
Guesthouse in San Benito
Magic Valley Outdoor Get-A-Way
Dec 28 – Jan 4
$91 per night
4.95 out of 5 average rating, 65 reviews
Guest favorite
Guesthouse in Harlingen
Studio Apartment, surrounded by our garden.
Dec 28 – Jan 4
$60 per night
4.95 out of 5 average rating, 40 reviews

Guest house rentals with a patio

Guest favorite
Guesthouse in Brownsville
Cozy retreat for nature lovers
Sep 7 – 14
$68 per night
4.96 out of 5 average rating, 77 reviews
Superhost
Guesthouse in Brownsville
Cozy Quarters near SpaceX
Jan 27 – Feb 3
$67 per night
4.82 out of 5 average rating, 51 reviews
Guest favorite
Guesthouse in Harlingen
Arroyo Colorado Cottage
Nov 13 – 20
$60 per night
4.87 out of 5 average rating, 94 reviews
Guesthouse in Brownsville
Casita Alessa
Jul 27 – Aug 3
$52 per night
New place to stay
Guesthouse in Brownsville
Cozy and quiet room
Jan 29 – Feb 5
$54 per night
New place to stay
Guesthouse in Brownsville
Lovely Little Studio and Balcony
Apr 26 – May 3
$68 per night
New place to stay
Guesthouse in Brownsville
Garden haven duplex: two studio apartments
Apr 16 – 23
$100 per night
New place to stay
Guesthouse in Brownsville
Historic garden flat with tropical patio
Aug 8 – 15
$85 per night
New place to stay

Guest house rentals with a washer and dryer

Guest favorite
Guesthouse in Brownsville
Entire luxury Guest Home close to SpaceX/Beach
May 12 – 19
$91 per night
4.94 out of 5 average rating, 48 reviews
Guest favorite
Guesthouse in Brownsville
Centrally located guesthouse!
Apr 14 – 21
$74 per night
4.9 out of 5 average rating, 29 reviews
Guesthouse in Harlingen
ONE BEDROOM COOL AND COMFORTABLE APARTMENT
Aug 25 – Sep 1
$42 per night
4.76 out of 5 average rating, 25 reviews
Guest favorite
Guesthouse in Harlingen
Tiny House Experience * Dog Friendly*
Mar 16 – 23
$65 per night
4.96 out of 5 average rating, 25 reviews
Guesthouse in Harlingen
Studio Apartment hideaway in Parkwood
Feb 2 – 9
$60 per night
4.9 out of 5 average rating, 31 reviews
Guesthouse in Los Fresnos
Bills Resaca Rental
Sep 26 – Oct 3
$132 per night
New place to stay
Guesthouse in South Padre Island
House w/ Private Pool (Walking distance to beach)
May 12 – 19
$414 per night
New place to stay

Destinations to explore