Guesthouse vacation rentals in Beaufort County
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Beaufort County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Beaufort County guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Port Royal
New place to stayCarriage House Port Royal and Parris Island
Sep 25 – 30
Guesthouse in Beaufort
4.94 out of 5 average rating, 395 reviewsMeridian Rd. Guest House Walk to Restaurants/Parks
Sep 18 – 25
Guesthouse in Beaufort
4.94 out of 5 average rating, 230 reviewsCozy private guest house
Jul 22 – 29
Guesthouse in Beaufort
4.98 out of 5 average rating, 359 reviewsThe Wren Guest House
Dec 20 – 27
Guesthouse in Bluffton
4.98 out of 5 average rating, 355 reviewsHickory Trace Carriage House
Dec 7 – 14
Guest house rentals with a patio
Guesthouse in Seabrook
5.0 out of 5 average rating, 45 reviewsAdorable guesthouse outside Beaufort
May 20 – 27
Guesthouse in Hilton Head Island
4.86 out of 5 average rating, 88 reviewsAlli B's air B and B-great country access off 278
Mar 31 – Apr 7
Guesthouse in Beaufort
5.0 out of 5 average rating, 7 reviewsThe Emerald Lodge
Sep 5 – 12
Guesthouse in Beaufort
4.63 out of 5 average rating, 41 reviewsWaterfront! Guest House!
Feb 27 – Mar 6
Guest house rentals with a washer and dryer
Guesthouse in Beaufort
4.93 out of 5 average rating, 273 reviewsRiver Retreat- Waterfront- Hot Tub- 1 MI from Parr
Sep 19 – 26
Guesthouse in Bluffton
4.99 out of 5 average rating, 118 reviewsCarriage House at 12 Lawrence
Aug 18 – 25
Guesthouse in Bluffton
4.96 out of 5 average rating, 126 reviewsModern and charming cottage!
Jul 9 – 16
Guesthouse in Bluffton
4.97 out of 5 average rating, 453 reviewsCharming Carriage house
Jul 5 – 12
Guesthouse in Bluffton
4.95 out of 5 average rating, 174 reviewsOld Town Bluffton Bungalow Apartment on Tidal Cove
Sep 20 – 27
Guesthouse in Beaufort
5.0 out of 5 average rating, 58 reviewsLow-country Carriage House
Sep 23 – 30
Guesthouse in Beaufort
4.64 out of 5 average rating, 22 reviewsCozy Pet Friendly 1/1 Guest House + Shared Yard
Aug 24 – 31
Guesthouse in Bluffton
4.95 out of 5 average rating, 20 reviewsGuesthouse in Old Town Bluffton
Oct 21 – 28
Destinations to explore
- Guesthouse rentals United States
- House rentals United States
- House rentals Charleston
- Guesthouse rentals Charleston
- House rentals Savannah
- Guesthouse rentals Savannah
- House rentals Hilton Head Island
- House rentals South Carolina
- Guesthouse rentals South Carolina
- Apartment rentals Beaufort County
- Rentals with outdoor seating Beaufort County
- Condo rentals Beaufort County
- Rentals with lake access Beaufort County
- Rentals with a patio Beaufort County
- Rentals with a kayak Beaufort County
- Rentals with a hot tub Beaufort County
- Rentals with beach access Beaufort County
- Hotel rentals Beaufort County
- Townhouse rentals Beaufort County
- Kid-friendly rentals Beaufort County
- Luxury rentals Beaufort County
- Waterfront rentals Beaufort County
- Family-friendly rentals Beaufort County
- Cottage rentals Beaufort County
- House rentals Beaufort County
- Beachfront rentals Beaufort County
- Rentals with a washer and dryer Beaufort County
- Pet-friendly rentals Beaufort County
- Rentals with a sauna Beaufort County
- Rentals with an accessible height toilet Beaufort County
- Fitness-friendly rentals Beaufort County
- Rentals with a fireplace Beaufort County
- Monthly Rentals Beaufort County
- Rentals with a fire pit Beaufort County
- Rentals with a home theater Beaufort County
- Villa rentals Beaufort County
- Rentals with breakfast Beaufort County
- Rentals with pools Beaufort County
- Cabins United States
- Treehouses United States
- Glamping United States
- Tiny Houses United States
- Beach Houses United States
- Campers and RVs United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes