Boutique hotel vacation rentals in Missouri

4.95 out of 5 average rating, 123 reviews

Hotel room in Washington

River Sirens Hotel Deluxe Suite

11 Room Boutique Hotel in beautiful Downtown Washington. Each room has: Private Entrance Guest Access - Key Pad, Free Parking, King Size bed, TV, Wifi, Hair Dryer, Individual A/C & Heat. Guests can enjoy a shower room featuring a changing area with separate vanity and water closet spaces. Every room as a very large balcony with river views. Each room is also equipped with a full kitchen featuring large refrigerators w/ ice dispensers, induction stove top, microwave, toaster, and coffee station.

4.83 out of 5 average rating, 103 reviews

Hotel room in St. Louis

Chic Ultramodern Minimalist Studio Loft + Patio

The Nash Loft is a stunning minimalist studio with 12’ ceilings, a fully-equipped kitchen with black stainless appliances and quartz countertops, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, a comfortable workspace with high-speed internet connection, bwalk-in closet, and a lovely patio overlooking the courtyard. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

4.97 out of 5 average rating, 33 reviews

Hotel room in St. Louis

Luxury Retreat, Hot Tub,En-Suite Bath, Location+

Discover refined elegance in The Riverfront Suite, where Gothic grandeur meets contemporary comfort. This distinctive retreat showcases original stained glass windows and exotic wood finishes . A plush queen bed and ambient electric fireplace create an intimate atmosphere, while the luxurious en-suite bathroom features heated floors, designer tile work, and a 2-person soaking tub. Take in panoramic city views from the shared rooftop hot tub. Perfect for couples seeking a romantic escape.

Hotel room in Springfield

4.94 out of 5 average rating, 215 reviews

“Camp Rockwood”at Rockwood Motor Court on Route 66

Rockwood Motor Court, on historic Route 66, was built in 1929. Each room is themed and furnished to the era of Route 66. Camp Rockwood pays homage to the important history of motor courts along the road. It is decorated with historic photos of Rockwood and other courts and motels. Newly renovated in 2019, you’ll enjoy clean and comfortable room amenities while experiencing authentic motor court lodging. Need more space? We have larger rooms or can package multiple rooms for your group.

Hotel room in Excelsior Springs

4.96 out of 5 average rating, 26 reviews

Beautiful Historic Suite

The Hope Loft Suite, located on the second floor of Casa Di Vite International Wine Café," in Excelsior Springs, Missouri, offers a delightful place to stay. This exquisitely furnished loft is crafted to reflect the style of the early 1900s, featuring a generous king-size bed and an additional room with a twin-size bed. Its location in historic downtown Excelsior Springs ensures easy access to diverse dining choices and shopping experiences. A private staircase in the back offers access.

4.87 out of 5 average rating, 718 reviews

Hotel room in St. Louis

Blue Spruce Room Queen Bed at BnB in CWE!

A Lovely room in a historical St. Louis home! The Blue Spruce Room is on the 2nd floor, and has a recently renovated and beautiful bathroom complete with a walk-in rain shower right next to it. The room has a desk, chair, lamp, table, Amazon Fire TV with basically every major streaming App, newly installed hardwood floors, and a Queen sized-bed. The room has two large windows for plenty of natural light with heavy blinds for sleeping in! Full use of the kitchen upstairs is available!

4.96 out of 5 average rating, 133 reviews

Hotel room in Hannibal

The Woodsman Suite

A third floor suite, facing the river with the train tracks only a couple blocks away. It took 2 months to do the ceiling. Carefully polished and placed the old lath in a specific design, the ceiling is a work of art. Eighty percent of the material used in this room is from re purposed lumber, either from this building or from a childhood barn built in the late 1800's. It will take you a while to notice every detail down to the toilet paper holder which is from an old barn post.

5 out of 5 average rating, 10 reviews

Hotel room in Osceola

Historic Commercial Hotel(1868)Karolyn Grimes Room

Rest a night or so in this 2nd floor room with Full size bed 1/2 Bathroom. Themed after Silver Screen Child Actress Karolyn "Zu Zu" Grimes, who has visited in the past and still does to this day. Karolyn is known for Her Silver Screen roles but maybe known best as ZuZu Bailey in "Its a Wonderful Life". Wonder the halls as you take a step back into History at The Historic Commercial Hotel and see the many historic items/guests memories of the Past. An area RICH in history.

4.81 out of 5 average rating, 78 reviews

Hotel room in Pacific

Queen room for two near wedding venues

The Pilot 1 is located on the second floor. This is a more affordable option than our other rooms. There is a queen bed, half bath en suite. There are 2 shower rooms located just outside the room for the 4 Pilot rooms to share. There are 2 Captain rooms on the first flor with a full private bathroom. There is a tv, desk, and mini fridge in the room. There is a large community space on the first floor with a kitchen and other activities. The pool is open seasonally.

4.95 out of 5 average rating, 43 reviews

Hotel room in Eldon

#8 A 1930’s Motor Court, Historic Randles Court

Family owned and operated! Built in the early 1930s, our recently restored rooms will take you back to simple times. The days of bus & railway rest stops, road-trips in the family car, and the quintessential motor court. Our town is alive with new and old businesses alike - places to eat, shop, and play for everyone in the family! We’re centrally located in downtown Eldon-just 15 minutes from the Lake of the Ozarks and 30 minutes from Jefferson City.

4.89 out of 5 average rating, 19 reviews

Hotel room in Seneca

The Den Suite

Cozy, country, and charming in the open floor plan of The Den. Guests will be able to enjoy the comforts of Small Town America; while, being minutes away from local attractions. Queen Log Bed sleeps 2 guest, kitchenette (stocked with dishes, coffee maker, and microwave), and includes such amenities as guest-controlled A/C and Heat, Wi-Fi access, Smart TV, and more!