Vacation rentals in Scott County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Scott County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite

Guest suite in Cape Girardeau

4.98 out of 5 average rating, 119 reviews

Cape Comfy! Close to SEMO & Capaha! CLEAN! 5 Star!

LaurenRating, 5 stars3 weeks ago

I cannot recommend this place enough! Daniel & Kendall were very responsive and checked in routinely to ensure that my stay went smoothly. Their place was very clean and centrally located! I will be back! 10/10

Guest favorite

Rental unit in Cape Girardeau

4.98 out of 5 average rating, 387 reviews

Beautiful Historic Boulevard District Apartment

BridgetRating, 5 stars6 days ago

Me and a couple of my girlfriends rented Frank and Gail’s apartment for a girls weekend. Their hospitality and kindness is unmatched. Their home felt like home to us. We stayed in and used their kitchen for a homemade meal and some mulled wine for the season. Their living area was the perfect spot for a movie marathon and board games. We have made some fond memories here and plan to return for another girls weekend. Thank you so much Frank and Gail. ❤️

Guest favorite

Rental unit in Cape Girardeau

4.95 out of 5 average rating, 208 reviews

Brand new 2 bedroom unit right in downtown Cape.

KaylaRating, 5 stars1 week ago

This is a great location! Walkable restaurants, bars, parks and the river. Very clean and comfortable, the towels and linens smelled so nice and were soft. The beds had plenty of pillows and are comfortable. We will stay here again!

Guest favorite

Home in Cape Girardeau

4.97 out of 5 average rating, 125 reviews

River Run

JohnRating, 5 stars1 month ago

The house was just as described. A very nice country home in a private setting looking down on the Mississippi River. It was clean, comfortable, and very inviting. What stood out the most in our stay was all of the extras. Anything that I may have forgotten was offered in friendly welcome baskets. The kitchen was stocked with spices and other cooking must-haves. Coffee service was well above expectation including various breakfast bakery items for our enjoyment. We enjoyed the screen porch, as well as the outside seating areas. We also took advantage of the BBQ grill which was a plus. This was perfect for our family gathering. I would look forward to booking again next year!

Guest favorite

Cottage in Cape Girardeau

4.98 out of 5 average rating, 198 reviews

Historic Cottage Walkable to Downtown Cape

MonicaRating, 5 stars4 days ago

We enjoyed our stay and appreciated that there was an iron and ironing board & full length mirror as we were in town for a wedding. 😊 The location was great to walk to restaurants and bars and we lucked out with both the farmers market and the waterfront festival going on while we were there. Stacy was great with responding and accommodating us with an early check-in. Would definitely stay there again!

Guest favorite

Barn in Cape Girardeau

4.96 out of 5 average rating, 149 reviews

Under the Stars - Farmhouse

GregRating, 5 stars1 week ago

Kevin's farmhouse was very nice, and as advertised. Nice remote quiet location for our one-night stay as we passed through the area. Good communication with Sarah and Kevin to when I reached out to them. Cell service was limited at the location for our particular carrier. My wife and I would stay again if in the area for future travel.

Guest favorite

Guesthouse in Cape Girardeau

4.93 out of 5 average rating, 471 reviews

Downtown Guesthouse- Romantic Getaway

BillRating, 5 stars2 weeks ago

Laurie is great. She is fast, responsive, and her property is perfect for being in downtown Cape. It is near several local restaurants and nightlife and pretty much all within walking distance. Make sure to ask her about the restaurant she owns-You will love it. If I could give her 10 stars, I would.

Guest favorite

Cabin in Cape Girardeau

4.92 out of 5 average rating, 218 reviews

Log Cabin w/ Hot tub - Near Casino & Downtown Cape

GabrielRating, 5 stars1 week ago

Beautiful home. Way to get to from downtown. Plenty of fun to have for a small get together with friends. Grew up in Cape but haven’t been back in nearly a decade. It was perfect for getting together to play some video games and pool with friends I haven’t seen in a long time.

Guest favorite

Cabin in Alto Pass

4.91 out of 5 average rating, 146 reviews

Hutchins Creek Cabin -2br- Wine Trail & Wilderness

GretaRating, 5 stars6 days ago

Our stay here was very peaceful and relaxing. Lots of comfy places to sit and curl up with a good book. There is no TV but wifi worked great and we were able to watch our current show on our tablet. Enjoyed the screened in porch and the fire pit area. Took daily walks down to the creek. Will definitely stay here again when we are back in the area.

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What guests are saying

The Cottage at Evergreen

5 out of 5 average rating, 49 reviews1 month ago

This lovely Airbnb is private and set away from the road. Very peaceful! The train sounds didn't bother us at all, or our dogs. Our dogs loved the garden and I could tell they were very comfortable staying at this place. I am very grateful we were able to bring them. The bed was very comfortable. The shower pressure was great and there was plenty of hot water. I'd definitely stay here again!

Guesthouse in Dexter

What guests are saying

1-bedroom tiny home located in historic Bloomfield

4.94 out of 5 average rating, 72 reviews1 week ago

Kristin was a great host and very responsive! She was accommodating with last minute changes. The space was exactly what I needed for a family visit when I need some solo time! Haha! The not so tiny house was stocked with great coffee, clean rooms and peace! Not much to do around but that’s expected coming from the city to the county! I felt right at home with the art in the airbnb!

Tiny home in Bloomfield

What guests are saying

Cozy and charming modern vintage style home

4.92 out of 5 average rating, 122 reviews5 days ago

In town for a wedding. Needed a place close by and with pets. This fit the bill. Spacious room to get ready and for our dog to get the zoomies out in the backyard. House was clean and in good shape. Jennifer was available to communicate but we had no concerns during the stay. There was a hint of underlying smoke but smelled clean. And the front entrance had a few loose bricks when walking up the steps. If in the area again, we would stay a second time.

Home in New Grand Chain

What guests are saying

Pop’s Country Cabin

5 out of 5 average rating, 67 reviews3 days ago

Pop’s Country Cabin, was the perfect setting by which to truly disconnect, and disconnect we did. From the privacy to serene setting, the experience felt surreal, that is to say beyond what might be hoped for. Our host, Tony was very responsive in his communications and had everything in good order for our arrival. Thanks soo much for sharing your little piece of paradise, and we hope to visit again. All the best!!

Cabin in Cobden

What guests are saying

Willow Acres - 2/2 home with BBQ and outdoor patio

4.8 out of 5 average rating, 20 reviews3 months ago

I suggest anyone to stay here first it was very clean private and comfortable beds, second it has a room for family’s with a baby which is a unique find.our son is not a baby anymore but if I was traveling and found this place it’s a very good idea that this host did as well as thoughtful it makes it’s an easy comfortable environment for a baby, I give a thumbs up for that. The outdoor space was very nice. The cows were a really cute surprise for my son. There are lots of books. Yes, there’s no TV like stated which was honestly a nice thing. I would definitely stay here again. The host is very responsive. Very polite. Thank you for allowing us to stay.!

Home in Advance

What guests are saying

Twisted Sassafras Treehouse

4.99 out of 5 average rating, 95 reviews5 days ago

My husband and I enjoyed a weekend getaway to the treehouse to celebrate our wedding anniversary! We live in the country, so this didn’t necessarily feel private to us, but the outdoor area was peaceful and relaxing! The hot tub was enjoyable and we enjoyed watching squirrels on the deck right outside the bedroom windows. Perfect little place for a couples getaway!

Treehouse in Cape Girardeau

What guests are saying

Unique Design | Walk Downtown/River | .5 mile SEMO

4.85 out of 5 average rating, 571 reviews6 days ago

We had a great girls weekend at Abby’s place! Squeaky clean. Clue was missing pieces so we weren’t able to play, and I would’ve loved some options for sugar/ creamer for the coffee. Beds were super comfy! Got some local Minglewood brews and Speck pizza!! Yumm!!

Rental unit in Cape Girardeau

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Vacation rentals for every style

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Popular amenities for Scott County vacation rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Other great vacation rentals in Scott County

Guest favorite

Cabin in Jackson

4.91 out of 5 average rating, 22 reviews

The Cabin at Timber Creek

KarenRating, 5 stars1 month ago

This was my family's first stay and we felt right at home. We loved the openness of the living and kitchen areas. There was ample bedroom and bath space for my family of 5 and our pups. Loved the stained concrete floors throughout the space! This made it easy to wipe up spilled water from the pup dishes :) If I could make one suggestion, it would be to add nightstands. Most of my family loves to read at night and having a place to put down our books would have been really convenient. Overall, we thoroughly enjoyed our stay! Thanks for having us, Amie!

Guest favorite

Guesthouse in Cape Girardeau

4.93 out of 5 average rating, 87 reviews

Cozy 1-BR guest house w/free parking on premises

LaurenRating, 5 stars2 weeks ago

I enjoyed my stay at Iona’s place! Was very clean and had everything I needed!

Guest favorite

Rental unit in Cape Girardeau

4.97 out of 5 average rating, 34 reviews

Downtown Condo on the River

MikeRating, 5 stars3 days ago

Great place, great location, sat on the balcony drinking a little wine and watching river traffic and trains. If ever back in Cape G would stay again!!!

Guest favorite

Loft in Marble Hill

4.92 out of 5 average rating, 77 reviews

Loft in the Ozark Foothills

AbbyRating, 5 stars1 week ago

Cindi's place was a hidden gem in Marble Hill. it was so chic and the details were well thought out. the space was functional and stylish. Perfect for our girls weekend! We would definitely stay at Cindi's again.

Guest favorite

Home in Bloomfield

4.9 out of 5 average rating, 10 reviews

Ridge Road Cottage

JeffRating, 5 stars1 month ago

We enjoyed our stay! Very clean!

Guest favorite

Tiny home in Jackson

4.92 out of 5 average rating, 25 reviews

The Cottage, Rusted Route Farms

KasieRating, 5 stars2 weeks ago

The staff is really friendly. The cottage is beautiful inside and very cozy. My husband and I enjoyed our stay.

Guest favorite

Home in Cairo

4.9 out of 5 average rating, 39 reviews

Traditional Family Home

LornaRating, 5 stars1 month ago

House was clean with many accomodations, games, chairs for yard, personal higiene items if needed. House was very nicely decorated with many small displays to promote well being.

Guest favorite

Cottage in Burfordville

5 out of 5 average rating, 52 reviews

Entire Cottage Nestled in the Woods

ChadRating, 5 stars2 months ago

Lara’s place was perfect for our wedding group. The home was immaculately clean, very spacious, and nicely furnished. Lara’s instructions made check in/out a breeze. We couldn’t have asked for anything more, and we highly recommend this beautiful rental.

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Monthly Rentals Scott County

Vacation rentals in Scott County

Top-rated vacation rentals in Scott County

Vacation rentals for every style

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Unique stays

Homes

Popular amenities for Scott County vacation rentals

Other great vacation rentals in Scott County

Cabin in Jackson

Guesthouse in Cape Girardeau

Rental unit in Cape Girardeau

Loft in Marble Hill

Home in Bloomfield

Tiny home in Jackson

Home in Cairo

Cottage in Burfordville

Destinations to explore