Vacation rentals in Madison County

Apartment in Edwardsville

A wooden pathway leads from the side of the house down a slope, bordered by freshly mulched flower beds featuring purple blooms. The area is surrounded by grass and trees, creating a natural and inviting approach to the guest suite entrance.

4.92 out of 5 average rating, 340 reviews

Edwardsville Apartment - The Woodland Suite

The apartment in the lower level of the home has recently been renovated, with a walk-out private entrance, a full kitchen & dining area, full bath, bedroom and a cozy living space. Situated just 35 minutes from downtown St Louis, in the safe and affluent community of Edwardsville, this property sits in a quiet cul de sac on a wooded lot right in the heart of the city. We are just a few minutes from the SIUE campus, Edwardsville HS, & I-270. Coffee/restaurants/shops/parks/trails just 2 min away.

4.97 out of 5 average rating, 206 reviews

A spacious basement recreation room features a ping pong table at the center, flanked by a futon and two wooden chairs. A foosball table is visible in the background, along with a dartboard mounted on the wall, providing various entertainment options.

Home in Granite City

Cozy 2-bedroom home minutes from ST. Louis, MO

Welcome to the Sheridan House. This cozy 2-bedroom home is located in a quiet neighborhood. It sets on a corner lot with a large back yard and a parkway across the street. Spend relaxing evenings on the patio, grilling your dinner. Or challenge your partner to a game of ping pong in the basement rec room. Centrally located, you can spend your days exploring attractions in Saint Louis, Mo, Alton and Edwardsville, IL. Just minutes from World Wide Technology Raceway, Busch Stadium, & the Arch.

4.97 out of 5 average rating, 147 reviews

A view from the bungalow's front porch features a grassy area and brick street. A decorative wrought-iron railing stands in the foreground, leading to the vista of the Mississippi River along the horizon, shrouded in misty weather and bare trees.

Bungalow in Alton

Bluff City Bungalow

On the bluffs overlooking the Great River Road and Mississippi River, “459” is a charming, comfortable bungalow located in the historic Christian Hill neighborhood of Alton, IL. This spacious three-bedroom home is the perfect setting for a relaxing getaway, family gatherings, your bridal party or a weekend visit to the Argosy Casino. It is also the perfect space for a business traveler needing an extended stay. Come enjoy a delightful home away from home. You may never leave the front porch!

4.89 out of 5 average rating, 165 reviews

The kitchen features wooden cabinetry and modern appliances, including a stainless steel refrigerator and a microwave. A clean countertop space is visible, with kitchen utensils neatly arranged. An archway leads to a dining area, where a light-colored table and chairs are set in a cozy atmosphere.

Home in Roxana

The House Next Door

This home offers the best of both worlds. The quiet, small-town charm with the quick access to big city amenities. Located 30 short minutes away from downtown St. Louis if you are coming for a vacation. Also located on a quiet street in a small town close to local parks, library, and ice cream shops. Local Attractions SIUE- 15 minute drive World Wide Technology Raceway- 20 minute drive Downtown St. Louis- 30 minutes drive St. Louis zoo- 35 minutes drive Six Flags St. Louis- 1 hour drive

4.93 out of 5 average rating, 228 reviews

A full-size hot tub is illuminated with soothing blue light, nestled on an outdoor patio surrounded by trees. A torch flickers nearby, adding to the serene ambiance. The night sky features a visible moon, creating a tranquil setting for relaxation.

Farm stay in Pocahontas

Hilltop Ranch Home on 25 acres bathed in starlight

Welcome to our Hilltop Ranch Home! You will find a relaxing getaway for your entire family or several couples. There is 1800 sq ft on the first floor including a master bedroom with ensuite bathroom boasting a jacuzzi tub, a fully stocked kitchen, gas fireplace, and an attached 2-car garage. In the walkout basement, there is a fourth bedroom, full bath and a TV area. A patio adjoining the dining room, a charcoal grill, and full-size hot tub-all perfect for entertaining your whole group.

Apartment in Edwardsville

A welcoming front porch features a sturdy wooden door with decorative glass panes. Two wicker chairs with plush cushions are positioned beside a small table, creating a cozy seating area. Natural light highlights the brick exterior and surrounding greenery.

4.98 out of 5 average rating, 114 reviews

Cozy Historic Downtown Edwardsville Charmer

Spacious and cozy with hardwood floors throughout. Beautifully restored to its original 1920’s glory. Set up to meet your needs. Clean, uncluttered spaces, full kitchen, Wi-Fi, and the basics for an easy stay. Third bedroom offers office space in addition to bunk beds. Relax on the front porch in this lovely neighborhood. Just a few blocks from main street’s offering of coffee shops, restaurants & entertainment. MCT bus stop across the street for easy access to SIUE & St. Louis.

A collage of vibrant downtown scenes showcases various establishments, including restaurants, cafes, and fitness studios. Notable signs read 'Cleveland-Heath,' 'Wildey,' and 'Recess.' A bold sign displays 'A Walk Down Main Street,' capturing the lively atmosphere and diverse options available to visitors.

4.96 out of 5 average rating, 119 reviews

The Kansas Street Guest House

Enjoy all that Downtown Edwardsville has to offer while staying at a local, luxury accommodation within walking distance to all the action. Less than 0.2 miles from the Courthouse, cafes, bars, breweries and restaurants! Whether you are traveling for business or pleasure, the Kansas Street Guest House can connect you to one of the most charming small towns in the Midwest. We can help you create an incredibly memorable stay, one in which you can eat, drink, and LIVE like a local.

Guest suite in Florissant

An outdoor patio area features a wooden deck surrounded by trees. A table is set with decorative cloth, accompanied by several black metal chairs. Lush green grass and a serene wooded backdrop enhance the peaceful surroundings.

4.82 out of 5 average rating, 125 reviews

Peaceful lower level apt in wooded neighborhood

A self contained apartment located in the basement of our home. 2 private entrances, self check-in and check-out. The neighbors in our cul-de-sac are trees and cardinals (the birds not the baseball players.) Quiet enough to work, work, work. Spacious enough to play, play, play. Christian Hospital 6 min, Airport 17 min, Busch Stadium 24 min, Convention Plaza 24 min, Downtown St. Louis 25 min. Very near nature reserves and confluence of Missouri and Mississippi Rivers.

4.85 out of 5 average rating, 109 reviews

Home in Alton

Backyard Seclusion Cottage

Private cottage 2 bedroom home. Built in 1860 Very secluded backyard with porch and patio. Located3 blocks from Great River Road ,bike and walking path and scenic views.Walking distance to downtown Alton, many restaurants, bars, bakery, shops, library. Grafton Is just up river road tourist enjoy water park, zip line, lots of places to eat n relax. Would welcome longer term stays , as …traveling nurses, or business travelers Send me an inquiry for rates n details. Thanks

4.94 out of 5 average rating, 144 reviews

A compact bathroom features a white vanity sink with storage underneath, paired with a modern toilet. Natural light enters through a window, illuminating the tiled floor. Wall shelves hold decorative items, while a towel rack displays neatly hung towels. A framed flower print decorates the wall.

Home in Godfrey

Aunt M's Place

The whole group will enjoy easy access to everything from this centrally-located home. There's plenty to see and do in the Riverbend area of Illinois. This home's proximity to the roads along the Mississippi, as well as the short drive to the Clark bridge or Amtrak station, make for easy access to everything the St. Louis area has to offer. The area is a major stopover for many migratory birds and boasts a number of sites for observing the birds during their travels.

4.92 out of 5 average rating, 145 reviews

Brick B&B - 3Bed 2Full Bath! Downtown Edwardsville

Welcome to the Brick B&B! Proudly located in Downtown Edwardsville, IL. This newly renovated house is located in a quite neighborhood, only 28 min drive from Downtown St. Louis. Enjoy a short walk or a quick drive to many local coffee shops, boutiques, spas, restaurants, and bars. Other local activities include: City Park only a 3 min walk, an entrance to the Madison County Transit bike path is a quick 6 min walk, & 10 min drive to SIUe campus. Permit # 031602

4.91 out of 5 average rating, 102 reviews

Home in Florissant

Cheerful 4-bedroom home with fireplace

Relax and recharge with family, friends and colleagues during your next visit to the St Louis area. This cozy home with newly remodeled bathrooms is located on a quiet cul-de-sac lined with mature trees in north county. Just minutes from highway 367 which can get you to many attractions in St Louis within 25 minutes. You can also hop right across the Illinois state line and get to towns like Alton, Granite City and Edwardsville in a short drive.

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Popular amenities for Madison County vacation rentals

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Other great vacation rentals in Madison County

Superhost

A well-appointed bathroom features a modern shower and an elegant vanity with a circular mirror. Soft lighting enhances the space, while earthy tones and marble flooring create a clean, soothing atmosphere. Essential toiletries are neatly arranged on the countertop.

Home in Florissant

4.87 out of 5 average rating, 45 reviews

Recently Renovated Townhome

PamelaRating, 5 stars5 days ago

The space was beautifully decorated and gave a peaceful vibe throughout. I appreciate the quick response from Aaron whenever I had a question. I definitely want to stay here again!

4.9 out of 5 average rating, 68 reviews

A modern kitchen is shown, featuring stainless steel appliances and gray cabinetry. The space is illuminated by natural light coming through large windows, with a distinct dining area visible in the background. Open shelves display dishes and decorative items, adding functionality and style.

Home in Glen Carbon

Glen Carbon Cottage

NovaLeeRating, 5 stars1 week ago

We LOVED our stay at Hannah’s home! My boyfriend and I love peaceful and relaxing environments when he visits and her home could not have been a more perfect fit for us. Hannah was extremely friendly throughout our stay and always responded quickly to any questions we had. The seating area in the kitchen and the bathroom skylight were to die for, too. Thank you for such a great stay Hannnah! Anyone considering staying here will not be disappointed. We will 100% be trying to return the next time he visits.

Apartment in Edwardsville

An open bedroom space features an exposed brick wall and a sliding barn door leading to a modern bathroom. Soft lighting fixtures hang from the ceiling, and a potted plant is placed on a wooden bench beside the window. Neutral colors and textures create a serene feel.

5 out of 5 average rating, 10 reviews

Main Street Loft

CarolynRating, 5 stars1 month ago

Amanda was an AMAZING host. We had a small issue and she was extremely communicative and had the issue resolved immediately. We loved everything about our stay and the surrounding area was a bonus. Would definately stay there again!

4.7 out of 5 average rating, 33 reviews

Charming Edwardsville Home: Walk to Downtown!

JaniceRating, 5 stars1 month ago

We loved our stay at The Seedling Guest House! It was very easy to find and has ample parking! We had enough room for our large pickup truck and U-haul trailer. The house is adorable! We loved the quaint boho-chic decor. It is so beautifully decorated and very comfortable and welcoming. The couch is super comfortable and seated 5 of us comfortably. The beds were very comfy, too. We were able to bring our Beagle and he was welcomed with food/water dishes and doggie treats! The host was very quick to respond, as well. The location is excellent, with some really nice restaurants and coffee shops within walking distance. We highly recommend Dewey's Pizza, Cafe Birdie, and Wasabi. All have really delicious food and excellent, friendly service. All are within walking distance of The Seedling. I wouldn't return to Sacred Grounds Cafe, though. The muffins were tasty, but that was all they had in the way of pastries. Not much variety, and the service was very cold and sub-par.

A close-up view of a black chicken is featured, showcasing its prominent red comb and attentive gaze. In the background, a rustic chicken coop can be seen, surrounded by natural wood shavings and a fenced enclosure.

4.97 out of 5 average rating, 33 reviews

Cozy Chicken Cottage

DavidRating, 5 stars1 day ago

Great place very quiet and peaceful. Really enjoyed our stay.

A round dining table is surrounded by four ornate chairs, each upholstered in a muted pattern. A floral centerpiece is placed in the middle of the table. Natural light enters through large windows, highlighting the light-colored cabinetry and decorative elements in the kitchen.

4.6 out of 5 average rating, 20 reviews

Elegant Home in Edwardsville

TynikaRating, 5 stars1 week ago

I love her placet was so clean and wash well stocked with needed supplies. l her set up it was beautiful and so comfortable i would stay here anytime I come back to visit. I recommend to anyone. I enjoyed my stay.

A map displays routes from a marked house to downtown St. Louis, showing a travel time of approximately 28 minutes. Key locations are highlighted, including major streets and landmarks along the way, indicating convenient access for guests exploring the area.

5 out of 5 average rating, 8 reviews

Cozy 1BR, near Edwardsville Downtown & SIUE

AnneRating, 5 stars2 weeks ago

This is a lovely home. It was clean and comfortable . The kitchen was well-stocked if you wanted to cook meals. I really appreciated the “extras” in the goodie bag that was waiting for me! The bathroom floor not only has lovely, vintage-looking tile, but it’s heated, too! The bathroom towels were large and luxurious. It is in a very convenient location- close to shopping and restaurants. I would definitely stay here again if I need lodging in the area.