
House vacation rentals in Guadalupe
Find and book unique houses on Airbnb
Top-rated house rentals in Guadalupe
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Guadalupe house rentals
House rentals with a pool

Hidden Views

Pool & view in Sta Rita Hills Wine Country, Lompoc

4bd w/ Pool/Hot Tub. Quiet and relaxing. Pets ok!

Fairway to Heaven

Getaway at the Highlands+Heated Pool+Hot Tub

FairView Lavender Estate

Ranch Style Home w/ Bikes! Heart of Wine Country

The Bridle Flat
Weekly house rentals

Centennial House - Old West meets Modern Farmhouse

Oceano Home with a View

Calle Del Flor🌼-Central Coast Wine Country Getaway

Romantic Retreat in SLO Wine Country near beach

Pacific Coast Highway Milkhouse

In the Heart of Los Olivos

Back Bay Getaway - Dog Friendly - Home in Los Osos

Santa Ynez Wine Country Escape
Private house rentals

Bayview Getaway

Steps to the Beach! Rooftop Deck! Firepit & BBQ!

Chelsea’s on Victoria

Entire Home - Luxurious California Coastal Retreat

Pleasant hills, king suite, EV Charger

Coastal Retreat - Sauna, Fire Pit & Outdoor Lounge

Home, comfortable to rest and relax. Welcome

|Safe|BBQ | Hot Tub| 4 Bedrooms| Deck With Views
Destinations to explore
- Southern California Vacation rentals
- Los Angeles Vacation rentals
- Stanton Vacation rentals
- Northern California Vacation rentals
- Channel Islands of California Vacation rentals
- San Diego Vacation rentals
- San Francisco Bay Area Vacation rentals
- San Francisco Vacation rentals
- Gold Country Vacation rentals
- Central California Vacation rentals
- Palm Springs Vacation rentals
- San Francisco Peninsula Vacation rentals
- Cabins United States
- Treehouses United States
- Tiny Houses United States
- Beach Houses United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Seal Beach
- Minuteman Beach
- Point Sal State Beach
- Paradise Beach
- Pismo State Beach
- Brown's Beach
- Au Bon Climat
- Refugio Beach
- El Capitan Beach
- Gaviota Beach
- Wall Beach
- Arroyo Quemada Beach
- Pirates Cove Beach
- Olde Port Beach
- Montaña de Oro State Park
- Sand Dollars
- Spooner's Cove
- Coon Creek Beach
- Bianchi Winery
- B & E Vineyard & Winery
- Morro Rock Beach
- Allegretto Wines
- French Camp Vineyards
- Natalie's Cove
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes