Pet-friendly vacation rentals in DeSoto County

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in DeSoto County

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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Home in Hernando

4.88 out of 5 average rating, 233 reviews

Hernando Hideaway (Entire Lakehouse)

Enjoy our 2000 sq ft lake house in a private peaceful community with panoramic views of the lake. We are a licensed BNB with DeSoto County and the State of Mississippi until the year 2035. (Lic # 20110070) You will have the entire lake house to yourself and we provide coffee and pastries for breakfast. We are 15 minutes from Tunica Expo, 5 minutes to Tunica National Golf Course, 10 Minutes to the casinos; 38 minutes to Beale St, Bass Pro Shop, Peabody Hotel, Graceland and The Lorraine Hotel.

Guest favorite

The exterior of a newly constructed brick home features a well-maintained lawn and a concrete driveway leading to a two-car garage. Colorful flower beds line the porch entrance, adding a touch of greenery to the inviting facade. The clear sky enhances the serene atmosphere.

Home in Southaven

4.9 out of 5 average rating, 68 reviews

Newly constructed, “award winning” cozy home

Newly constructed home built in 2019. The neighborhood is very quiet and safe. The home is 10 minutes from Memphis Airport; 2 minutes from I-55; less than 15 minutes from downtown Memphis, Orpheum Theater, FedEx Forum, Beale Street, Bass Pro Shop, and many other attractions; 2 minutes from North Creek Golf Course; 5 minutes away from restaurants, malls, grocery stores, Walmart, Target, movies theaters, etc. The perfect place to relax after a long eventful day! 6 exterior security cameras.

Guest favorite

A versatile living space features a large wall-mounted television opposite a desk with an adjustable lamp. A classic arcade machine adds a playful touch. Natural light enters through two windows, complemented by decorative mirrors and a potted plant in the corner.

Home in Southaven

5 out of 5 average rating, 21 reviews

Your Stay at The Top of Mississippi

*Stylish Renovated Townhome in Southaven, MS* - Features 2 bedrooms, each with its own vanity. Primary bedroom with king bed, the second bedroom features two full-size beds. - Free wifi, fully equipped kitchen, washer and dryer. - Situated just 12 minutes from Memphis Airport, 20 minutes from downtown Memphis, and only minutes from local restaurants and parks. Plus, it’s only 5 minutes from the local hospital, making it a great choice for medical professionals or visitors. -No smoking

Top guest favorite

A living room area features a futon and two armchairs, complemented by a coffee table. A large window allows natural light to fill the space, and a potted plant adds a touch of greenery. Modern light fixtures provide additional illumination.

Home in Southaven

4.95 out of 5 average rating, 84 reviews

Green house

The Green House is centrally located in Southaven, Mississippi, a small town just south of Memphis, Tennessee, few minutes away from Interstate 55, Tanger outlets, Southaven Towne Center, Silo Square, Landers Center, and Snowden Grove. It’s surrounded by all types of restaurants, including American, Italian, Korean, Japanese and Southern Cuisine. It is about 20 minutes to Midtown and Downtown Memphis, 15 minutes to Graceland and 25 minutes from all the casinos in Tunica, Mississippi.

Top guest favorite

The exterior of a modern farmhouse showcases a light-colored façade, framed by neatly trimmed landscaping. A welcoming entrance features a concrete pathway leading to the front door, flanked by symmetrical black railings and decorative shrubs, with a garage visible to the left.

Home in Southaven

4.94 out of 5 average rating, 18 reviews

The Luxury Cabin Home—In the heart of Southaven

Welcome to the Luxury Cabin Home—boasts a unique wooden interior design and nestles on a private and peaceful 2-acre lot w/ a big natural pond in the back—this city cottage offers comfort, relaxation & easy access to places of attraction—3 mins from Snowden Grove Park & Silo Square, where you will find all local restaurants, 2 minutes from Landers Center and Tanger Outlets, 20 mins from downtown Memphis, 10 mins from Memphis Int'l Airport and grocery stores just around the corner.

Top guest favorite

A guesthouse is nestled among green trees and lush grass, with a pathway leading to a bright red door. Two small chairs are positioned in front of the entrance, inviting guests to relax in the outdoor space.

Guesthouse in Hernando

4.99 out of 5 average rating, 122 reviews

Cozy 2 Bedroom Guesthouse in a Relaxing Setting

Our two bedroom, two bath guesthouse is the perfect get-a-way from it all, yet close enough to everything you're looking to do: 3 minutes to the historic Hernando Town Square, 10 minutes to the MS River Delta and Historic Hwy 61, 12 minutes to Tanger Outlets & Landers Center in Southaven, 20 minutes to Snowden Grove Ballfields & Amphitheatre in Southaven, 23 minutes to Tunica Casino Strip, 25 minutes to Midtown/Downtown Memphis, 1 hour to Oxford, MS and 1 hour to Clarksdale, MS.

Top guest favorite

The studio features a spacious sleeping area with a king bed, complemented by a soft green sofa and a decorative area rug. A dining table with chairs is positioned nearby, and warm wood cabinetry can be seen in the background, opening to the galley kitchen.

Home in Hernando

5 out of 5 average rating, 33 reviews

Studio Downtown! Clean, great location, sleeps 4!

Enjoy a stylish modern experience at Studio Downtown! Featuring 1 king bed and queen size sofa bed. Galley kitchen w/Keurig coffee machine, microwave, range and refrigerator. Full bathroom with walk in double shower. Laundry room with washer and dryer. Smart 65” tv and Wi-Fi. Very safe location in the historic district of downtown Hernando. Enjoy the multiple outdoor seating areas and corn hole boards. Within walking distance to restaurants and the town square. Owner/Agent.

Guest favorite

The exterior of the new construction home is showcased, featuring a combination of light green siding and brick detailing. A wooden post supports the overhang by the entrance, while neatly arranged landscaping includes subtle shrubs and grass in the foreground.

Home in Southaven

4.79 out of 5 average rating, 19 reviews

Stylish Cottage in Silo Square near Snowden Grove

This stylish new construction home is a home away from home. It is centrally located in the heart of the Snowden Grove community in Silo Square. This location not only boosts close proximity to Snowden Grove Park (Concert Amphitheater, Baseball, Soccer, Tennis), it is steps away from local shops and restaurants. 10 miles to Memphis Airport, 12 miles to Graceland Mansion. The home offers optional concierge service (i.e. stocked fridge/pantry) at an additional cost.

Top guest favorite

The compact kitchen features wooden walls and open shelving, displaying colorful pots and dishes. A stainless steel refrigerator and countertop appliances are visible, along with a sink and wooden countertop. A mounted artwork of a Longhorn adds character to the space.

Farm stay in Southaven

4.99 out of 5 average rating, 109 reviews

The Longhorn Tiny House: Farm Stay Near Memphis

Escape to The Longhorn House, a cozy tiny house on 38 acres of rolling hills near Memphis, TN. Explore the countryside, fish or canoe on Blue Haze Lake, and enjoy sunsets with grazing miniature Longhorns. Relax at the outdoor seating area, grill out, or watch a movie under the stars at our outdoor theater. Inside, enjoy memory foam bedding, TVs, records, and board games. Just minutes from Memphis and Graceland, this is your perfect escape to nature and comfort.

Top guest favorite

A spacious living area is furnished with multiple seating options, including soft couches and armchairs. Natural light filters through large windows, complementing the neutral tones of the decor. A coffee table centers the room, surrounded by decorative elements and a calming rug.

Home in Byhalia

5 out of 5 average rating, 22 reviews

Elegant Country Retreat

Welcome to Your Perfect Getaway! Experience the best of comfort and convenience in our brand-new 4-bedroom, 3-bathroom Airbnb, located in a serene and family-friendly neighborhood. Whether you're traveling for work or leisure, our home offers the ideal retreat for your stay. Book your stay today and experience the perfect blend of tranquility and convenience. Our home is ready to welcome you for an unforgettable stay!

Guest favorite

The exterior of the house is shown, featuring a modern design with a covered porch and two symmetrical large windows framed in dark accents. A stone chimney rises from one side, while well-maintained grass lines the pathways leading to the entrance.

Home in Hernando

4.92 out of 5 average rating, 13 reviews

Relaxing Row House in Downtown Hernando

Enjoy this relaxing 2-bedroom 2-bathroom house in walking distance to restaurants, bars, and boutiques for shopping. This relaxing home is located in downtown Hernando, Mississippi. With less than a 30 minute drive to Memphis, a 10 minute drive to Southaven, and less than an hour to Oxford, this location offers various day trip opportunities!

Guest favorite

A cozy living area features a gray sofa and armchair, arranged around a circular coffee table. A television is mounted above a stylish fireplace, while a decorative wall piece adds character to the space. Soft lighting is provided by a floor lamp and a side table lamp.

Home in Southaven

5 out of 5 average rating, 17 reviews

Southaven Hideaway near Shopping

Cozy and secure modern home with relaxing back patio in quiet Southaven neighborhood! Minutes from Starbucks, outlet malls, restaurants, and shopping…easy access to I-55 and the Memphis Airport. Premium bedding, well equipped kitchen, garage parking and blazing WiFi make this a perfect travel home!