Saint Charles vacation rentals

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Top-rated vacation rentals in Saint Charles

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

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  1. Hotel room
  2. Saint Charles
1st Capitol Mansion Boutique Hotel - Suite 301

This unit is a hotel style unit that is located in the heart of downtown historic St. Charles. It's located right across the street from a coffee shop, wine bar and the oldest local pub in St. Charles. It is just a few blocks away from all of the shopping and restaurants on Main St. The mansion was built in 1902 and still holds all of the charm from back then. This is a private suite with it's entrance just up the stairs from the main front door of the mansion.

$100 per night
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  1. Entire rental unit
  2. Saint Charles
Stay on Main!

Stay on Main! Cozy studio apartment directly on Main Street in St. Charles MO. Studio that has a staircase directly to the north end of Main Street, you can be on Main along the shops and restaurants in seconds. Unit has street parking only, and the staircase is shared with another short term rental that I also operate. Free wifi, coffee. There is a full bathroom, kitchen space and a king bed. Unit is brand new, it can be noisy on weekend evenings from the street.

$144 per night
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  1. Entire rental unit
  2. Saint Charles
Great Vibes on Main Street in Historic St. Charles

“It doesn't get better than this!” "Meilleur séjour de ma vie." Read my REVIEWS! My place is close to family-friendly activities, nightlife, concerts, casino, the airport, and history. You’ll love my place because of the high ceilings, the furnishings, the wood floors, the view, location, and the coziness. My place is good for solo adventurers, newlyweds, couples, and business travelers. I’ve hosted 230 travelers since 2017.

$104 per night

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Stay near Saint Charles's top sights

Photo of Ameristar Casino Resort Spa St. Charles
Ameristar Casino Resort Spa St. Charles12 locals recommend
Photo of Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis3 locals recommend
Photo of The Family Arena
The Family Arena3 locals recommend
Photo of Dave & Buster's
Dave & Buster's5 locals recommend
Photo of Streets of St. Charles
Streets of St. Charles12 locals recommend
Photo of Bar Louie - Streets of St. Charles
Bar Louie - Streets of St. Charles3 locals recommend

Other great vacation rentals in Saint Charles

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  2. Saint Charles
The Rose Cottage -a short walk to Historic Main St
$146 per night
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  1. Entire home
  2. Saint Charles
301GUESTHOUSE/ SUPERHOST/SHOP DISCOUNTS/KATY TRAIL
$131 per night
  1. Entire home
  2. Saint Charles
The Jewel on 5th! 2br/2b-Short walk to Main Street
$182 per night
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  1. Entire home
  2. Saint Charles
Rustic Handcrafted Japanese-Style Home by OldTown
$164 per night
  1. Entire rental unit
  2. Saint Charles
Midnight In Paris
$132 per night
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  1. Entire rental unit
  2. Saint Charles
Updated Studio Apartment Available near Main St!
$136 per night
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  1. Entire townhouse
  2. Saint Charles
THE MADISON HOUSE #1 - HISTORIC AREA in ST CHARLES
$194 per night
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  1. Entire home
  2. Saint Charles
1st Capitol Mansion - Charles Schibi Suite - 101
$164 per night
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  1. Entire rental unit
  2. Saint Charles
2 Bedroom, 1 Bath Apartment, Short Walk to Main!
$162 per night
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  1. Private room
  2. Saint Charles
top floor unit 1bdrm
$106 per night
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  1. Entire townhouse
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Colorful 2-Bed Townhome Next to Park w/ Garage
$128 per night
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  1. Entire rental unit
  2. Saint Charles
The Ella Rose Guest Suite in Historic St Charles❤️
$117 per night