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Saint Charles vacation rentals

Book unique vacation rentals, houses, and more on Airbnb

Top-rated vacation rentals in Saint Charles

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

Superhost
Home in Saint Charles
301 Guesthouse/SuperHost/Fast WiFi/Katy Trail/
Our 301 Guest House is new and completely remodeled in 2018! It’s ideal for one or two people with beautiful furnishings, great queen bed, lots of amenities, full kitchen, with big back yard and patio to enjoy outdoors too! Cable and FAST WiFi! Enjoy light Breakfast! BEST location, Great events year round within walking distance, with being only about 2 blocks from S. Main St, where there are about 100 gift shops n restaurants! Katy Trail is so close, with Spring, Summer, Fall and Xmas events!
$128 per night
Superhost
Apartment in Saint Charles
Pop Lucks Guest Suite Steps From Historic Main St
Welcome to Pop Luck's Guest Suite! This adorable gem represents everything you love about Old St. Charles. This cozy suite is just steps away from the heart of Main Street, restaurants, and all the action St. Charles has to offer. Pop Luck's is a charming one-bedroom, with an open and airy living room and kitchen. It has natural light and high ceilings throughout. It's farmhouse cottage decor makes for a relaxing place to rest. Also, check out our sister suite The Ella Rose, right next door.
$113 per night
Superhost
Home in Saint Charles
Bright & Cozy Shotgun 1 Block from Historic DT.
Admire this unique historic home's design with brand new amenities and antique details that give a fresh and charming feel. Built in the 1930's, this half of the duplex has a typical shotgun layout with ten-foot ceilings giving a spacious feel. The front door leads directly to the living room, then into the bedroom, both of which have the original hard wood floors. The back of the house has the kitchen, with exposed brick, a dining area, and a bathroom with a washer and dryer.
$107 per night

Stay near Saint Charles's top sights

Ameristar Casino Resort Spa St. Charles42 locals recommend
Hollywood Casino St. Louis20 locals recommend
The Family Arena12 locals recommend
Sugarfire Smoke House5 locals recommend
Walmart Supercenter7 locals recommend
St. Charles Convention Center6 locals recommend

Other great vacation rentals in Saint Charles

Superhost
Bungalow in Saint Charles
Patio House, secluded in heartbeat of Main Street
$127 per night
Superhost
Apartment in Saint Charles
Lewis and Clark Suite - 1 Bed/1 Bath on Main
$128 per night
Superhost
Home in Saint Charles
Charming 2 Bedroom Home in Historic Frenchtown!
$171 per night
Superhost
Apartment in Saint Charles
Spacious 2-Bedroom Abode Just Moments from Main St
$133 per night