Skip to content

Vacation rentals in St. Charles County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in St. Charles County

Guests agree: these stays are highly rated for location, cleanliness, and more.

Apartment · Saint Charles
The Ella Rose Guest Suite in Historic St Charles❤️
Welcome to The Ella Rose Guest Suite! This brand new gem represents everything you love about Old St. Charles. This cozy suite just steps away from the heart of Main Street, restaurants, and all the action St. Charles has to offer. The Ella Rose is a charming one-bedroom, with an open and airy living room and kitchen. It has natural light and high ceilings throughout. It's farmhouse cottage decor makes for a relaxing place to rest. Come sit and listen to music of our outdoor bubbler rock.
Nov 4 – 11
$94 per night
Cottage · Saint Charles
The Rose Cottage -a short walk to Historic Main St
The Cottage has a 2 guest maximum Updated 1 bedroom home a three minute walk from historic Main Street and festivals like Oktoberfest, Christmas Traditions and Festival of the Little Hills, the Lewis and Clark Boat House, Foundry Arts Center, Katy Trail and more! Located 10 minutes from the airport , 2 minutes from Ameristar Casino and Bass Pro Shop. 25 minutes from downtown St. Louis, The Arch, Forest Park, Zoo, Art Museum, History Museum and Busch Stadium-home of Cardinals Baseball!
Dec 5 – 12
$119 per night
Bungalow · Saint Charles
Patio House, secluded in heartbeat of Main Street
The Patio is nestled in the heart of historic St. Charles a few steps from Main Street, Katy Trail, Missouri River, Antique and Boutique Shopping, Restaurants Bars and More, Several Wedding venues are within walking distance of the property as well. In addition to your well appointed unit, this property has as much outside as it does in. Take your coffee, wine, water and enjoy our patio, complete with fire table, dining table edged with lush plantings for privacy.
Jan 17 – 24
$137 per night

Vacation rentals for every style

Get the amount of space that is right for you

  • Homes
  • Hotels
  • Unique stays

Other great vacation rentals in St. Charles County

Private room · Saint Charles
Delightful room close to the St. Louis airport.
Aug 16 – 23
$65 per night
Apartment · Saint Charles
Main Street Living! 2 Bedroom Unit right On Main!
Nov 7 – 14
$123 per night
Home · Saint Charles
Cozy 1880s House, Walk to Old Main Street
Feb 8 – 15
$87 per night
Apartment · Saint Charles
Great Vibes on Main Street in Historic St. Charles
Feb 3 – 10
$120 per night
Home · Saint Charles
Cole's cozy cottage
Jan 6 – 13
$108 per night
Guest suite · Saint Charles
Super Comfy Walkout Basement Unit - patio entrance
Oct 9 – 16
$81 per night
Home · Saint Charles
Historic Duplex
Mar 15 – 22
$130 per night
Home · Saint Charles
The Benton House - With fenced yard!
Apr 8 – 15
$109 per night
Private room · Wentzville
Midwest Guest Room "G"
Oct 11 – 18
$45 per night
Home · Saint Charles
Charming 2 bedroom home in Historic Main Street
Feb 16 – 23
$116 per night
Private room · Saint Charles
Attractive Private Room in Great Neighborhood
Aug 26 – Sep 2
$79 per night
Private room · Saint Charles
The Teal Room: 1 bedroom in Saint Charles
Mar 31 – Apr 7
$44 per night