Vacation rentals in San Luis Obispo

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Top-rated vacation rentals in San Luis Obispo

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Top guest favorite
A wooden gate with a decorative wreath opens into a welcoming path surrounded by lush greenery and vibrant flowers. The cottage's exterior is partially visible, providing a glimpse of a charming entrance and well-maintained landscaping.
Apartment in San Luis Obispo
5 out of 5 average rating, 125 reviews

Very Spacious Edna Valley Luxury Apartment

The Nottage is a welcoming cottage-like apt. located in the heart of the Edna Valley. Luxury and style afford you upgraded comfort in a beautiful garden setting. At approx. 1000 sq. ft. and no shared walls, you will enjoy quiet living with plenty of space for longer stays. Central but peaceful - Pismo & Avila Beaches, and downtown SLO, are 10-15 mins. away. Guests have full access to the Pickle and Bocce ball courts on the property. We are only minutes away from multiple well-known wineries.

Top guest favorite
A charming garden area is framed by brick pathways, with a wooden table and chairs positioned nearby. Lush greenery and various plants create a serene outdoor atmosphere, while a wooden gate provides privacy and access to the space. The ground appears damp, suggesting recent rain.
Guesthouse in San Luis Obispo
4.97 out of 5 average rating, 611 reviews

SLO Guesthouse - quiet - near downtown - #115545

Private studio with it's own entrance located in lovely SLO. Includes a queen size Murphy bed (people rave about the comfort of this bed), 3 piece bathroom, table & two chairs, desk, closet, TV, WiFi & kitchenette. Coffee, tea with fixings are provided. 4 blocks from the downtown cultural-hub, hip restaurants, Farmer's Market, the Historic Mission and more. The Edna Valley wine country is 5 minutes away and the Beach is 10 minutes away. The Perfect Location to come experience the "SLO Life"!

Top guest favorite
A newly built 1-bedroom home is set against a backdrop of rolling green hills. The structure features a modern design with a dark exterior and a covered porch area. A small dog sits on the concrete driveway, adding a welcoming touch to the scene.
Home in San Luis Obispo
4.99 out of 5 average rating, 119 reviews

Hilltop Horizon: Centrally Located+Panoramic Views

Newly built,secluded 600 sq ft 1 bedroom home with panoramic views of all of San Luis Obispo. Home is centrally located at 7min from both downtown &/or wineries, 3 miles to Cal Poly- but is completely quiet with no traffic on our multi acre property. This home shares the driveway and parking with our family’s main house, but the home has been designed for the two sets of 8ft glass sliders to have unobstructed views while maintaining complete privacy. We are 15 minutes to Avila and Pismo Beach.

Guest favorite
A vintage-inspired kitchen features white cabinetry and open shelving displaying a variety of decorative dishware. A well-appointed stove and sink are included, along with subtle decor elements such as potted plants and a floral arrangement, creating a warm and welcoming environment.
Apartment in Downtown SLO
4.98 out of 5 average rating, 302 reviews

Eclectic apartment in the heart of downtown SLO.

This charming, newly updated, 1 BR apartment is part of an 1883 Folk Victorian in the heart of SLO's downtown historic district and was recently added to the California Master List of Historic Resources as 'The D.M. & Carrie Proper Meredith House'. This cozy apartment offers convenience, style, safety, and privacy - all while being just a two-minute walk to all your favorite bars, restaurants, cafes, movie theatres, and shops. Your hosts aim to provide you with an amazing 5-star experience!

Top guest favorite
A spacious bedroom is equipped with a large bed draped in a decorative quilt, complemented by colorful pillows. Two bedside tables with lamps are placed beside the bed. A small dining table and chair set sits by a window, allowing natural light to illuminate the room.
Apartment in San Luis Obispo
4.97 out of 5 average rating, 358 reviews

Mountain View Studio - No Cleaning Fee!

Your home away from home is close to Cal Poly, hiking, art and culture, great views, restaurants, wineries, and several beaches. This spacious studio apartment has a super-comfy bed and is located in a quiet neighborhood with easy access to all things SLO. We use only natural, organic cleaning products, and all sheets and towels are of high-quality cotton. Kitchenette stocked with coffee, tea, etc. Smart TV. Licensed in the city of SLO ( #113984), so a required 13% lodging tax is included.

Top guest favorite
A backyard patio features a circular fire pit surrounded by comfortable seating. String lights hang overhead, providing a warm glow. Greenery lines the perimeter, and the space is paved with stone tiles, creating an inviting area for relaxation and socializing.
Home in Downtown SLO
5 out of 5 average rating, 181 reviews

1884 Elegant Home: Fire Pit, Tesla Tech, Near DT

Step into history at this charming 2-bedroom railroad house in downtown SLO. Enjoy its preserved heritage, from the 11-foot tall ceilings to the spacious kitchen. Sleep luxuriously on Purple mattresses in both bedrooms. Sit back next to the fire pit in the backyard, it's just a 7 min. walk to downtown & next to 5 restaurants including Sally Lou's coffee shop, Terrace Hill trail head & the train station. Experience SLO's charm like never before with this perfect location home. Book a stay!

Top guest favorite
Barn in Atascadero
4.99 out of 5 average rating, 182 reviews

The Barn at Old Morro

The Barn at Old Morro is a refreshing and beautiful space centrally located to all the Central Coast has to offer! Tastefully appointed and well stocked, the barn is the perfect getaway for Paso Robles wine country, the Cayucos/Cambria/Morro Bay Coast, San Luis Obispo shopping or exploring the gorgeous Big Sur coastline! Set in a beautiful spot at the lower end of our property under a mature and majestic grove of oak trees with overhead twinkling bistro lights.

Top guest favorite
The exterior of The Fish House features a spacious deck surrounded by natural rocks and greenery. Seating areas include lounge chairs and a table beneath a sunshade. A barbecue grill is positioned nearby, inviting outdoor gatherings in a serene setting.
Cottage in San Luis Obispo
4.99 out of 5 average rating, 369 reviews

Slo Fish House Retreat

Good bye city life ! The Fish House is an amazing addition to our stunningly beautiful 29 acres! Views from the dock are guaranteed to take your breath away. Let the awe of nature rejuvenate your soul as you enjoy all that is San Luis Obispo. Whether you are coming to town for pleasure or for work, we are perfectly located just 10 minutes from downtown SLO, the airport, Edna Valley wineries, and Cal Poly; and 20 minutes from Avila or Pismo Beach.

Top guest favorite
A bright living area features a comfortable sofa and two accent chairs, surrounded by natural light from large windows. A coffee table with a decorative centerpiece sits on a patterned rug, while a flat-screen television is mounted above the fireplace, enhancing the cozy atmosphere.
Home in Downtown SLO
4.96 out of 5 average rating, 420 reviews

The Downtown House SLO with Private Parking

Charming 1920s bungalow in the heart of downtown San Luis Obispo! Walk to top restaurants, coffee shops, parks, and the famous Farmers Market. Perfect for SLO Marathon runners—just a mile from the starting line. Original details + modern upgrades, A/C, full kitchen, laundry, and parking. Ideal for guests who love vibrant, walkable neighborhoods. We’re locals and happy to share our favorite hikes, wineries, and spots to explore!

Top guest favorite
A dining area features a wooden table surrounded by four chairs, complemented by a decorative rug. Exposed beams and ductwork enhance the industrial style. Natural light fills the space through large glass walls, revealing the adjacent kitchen and bedroom area.
Home in Downtown SLO
4.98 out of 5 average rating, 256 reviews

Mid Century Modern Loft Downtown SLO

This unique place has a style all it's own. Mid century modern loft located just a few blocks from downtown SLO. 10 min walk and 3 min drive to all the great shops and restaurants SLO has to offer. Thick glass walls in the bedroom allow for an open loft like experience. Many fun details throughout the place create a truly unique vibe. This 800sf loft located upstairs above a salon is private and has designed parking.

Top guest favorite
The cabin's front porch features rustic wooden steps leading to a welcoming entrance framed by greenery. Two cozy chairs and a small table sit under the awning, while warm lights illuminate the space, inviting relaxation amid the natural surroundings.
Guesthouse in San Luis Obispo
5 out of 5 average rating, 122 reviews

Castlebrook Cabin

Escape to Castlebrook Cabin, a private retreat in See Canyon surrounded by apple orchards and vineyards. Walk to Gopher Glen Apple Farm or reach Avila Beach in 10 minutes for kayaking, fishing, and the Bob Jones Trail. Explore Pismo Beach and San Luis Obispo just 15 minutes away, then return to your cozy cabin to sip local wine and enjoy sweeping canyon views. Perfect for a peaceful escape or coastal adventure.

Top guest favorite
The open concept living and sleeping area features a queen bed and a twin sofa. Natural light enters through two windows, highlighting the neutral color palette. A flat-screen TV is mounted on the wall, and a small side table provides decorative accents.
Bungalow in Downtown SLO
4.99 out of 5 average rating, 140 reviews

Close to Downtown SLO

Enjoy this clean 420 sqft space in a great SLO location. Close distance to town, restaurants, bike paths & hiking. Private entrance. Open concept style, queen bed and twin sofa option. Large walk-closet with extra bedding and towels. Fully equipped kitchen: refrigerator, oven, microwave, dishwasher, reverse osmosis for drinking water & garbage disposal. Beautifully done bathroom with large shower & vanity

Popular amenities for San Luis Obispo vacation rentals

Quick stats about vacation rentals in San Luis Obispo

  • Total rentals

    400 properties

  • Total number of reviews

    38K reviews

  • Family-friendly rentals

    170 properties are a good fit for families

  • Pet-friendly rentals

    110 properties allow pets

  • Rentals with a pool

    30 properties have a pool

  • Rentals with dedicated workspaces

    200 properties have a dedicated workspace

Your guide to San Luis Obispo

All About San Luis Obispo

An equal distance from the wildlife haven of Morro Bay and laid-back Pismo Beach, the small city of San Luis Obispo sits midway between Los Angeles and San Francisco in California’s central coast region. As one of the state’s oldest communities, it’s filled with culture and history, featuring a 19th-century city center surrounded by a restored 18th-century mission, and local homes and businesses often have a Spanish architectural influence.

Aside from dreamy views of the Santa Lucia Mountains and coastline, a major draw in San Luis Obispo is its location in the state’s third-largest wine-producing county, and you can pair your local albariño with dinner made with ingredients sourced from the numerous local farmers markets. Vacation homes here are also well positioned for exploring the local art scene — you’ll find pop-up galleries sitting alongside permanent exhibitions — and kayaking, swimming, and hiking are all within easy reach.


The best time to stay in a vacation rental in San Luis Obispo

Spring and summer are the best times to book vacation rentals in San Luis Obispo to see the lush surrounding vegetation at its peak. These are also the best times to visit nearby vineyards and explore trails along the beach. Early fall is your chance to see the change of foliage at Lopez Canyon and enjoy the outdoors before temperatures start to dip. The weather can be somewhat unpredictable here, so pack layers along with an umbrella or raincoat when traveling outside of the summer season.

January and February are characterized by cooler, greyer days, and you’ll be one of fewer visitors on the nearby beaches. The city’s film festival takes place in March, with screenings in downtown San Luis Obispo.


Top things to do in San Luis Obispo

Edna Valley

Just a short drive south from San Luis Obispo is Edna Valley, a region known for its cluster of wineries and award-winning pinot noir — you’ll find established brands and under-the-radar producers offering tastings at their vineyards. Visit the Old Edna Townsite for a picnic with wine and cheese or nearby Arroyo Grande Valley to browse the local markets.

San Luis Obispo Museum of Art

Perched on Monterey Street downtown, the San Luis Obispo Museum of Art showcases California artists across three galleries, focusing on contemporary works. Head to SLOMA, as the locals call it, for a taste of local prints, sculptures, and paintings. If you time your visit right, you can join one of the monthly talks that take you through the exhibits.

Montaña de Oro State Park

Ten miles west from the city is Montaña de Oro State Park, a popular spot thanks to its abundance of trails for cyclists and hikers, beautiful peaks, and sandy beach. Nature lovers are also drawn here for the seabirds and otters. Take one of the coastal trails by Spooner’s Cove for views of the ocean and unique rock formations.

Frequently Asked Questions

  • Where should I stay in San Luis Obispo?

    Make yourself at home in San Luis Obispo by choosing from our most frequently booked neighborhoods. We have over 370 vacation rentals in Japantown, over 370 vacation rentals in Meadow Park, and over 370 vacation rentals in Downtown SLO.

  • Are there vacation rentals with a dedicated workspace in San Luis Obispo?

    Yes! Work meets play with ease at over 200 vacation rentals in San Luis Obispo featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Are there pet-friendly vacation rentals in San Luis Obispo?

    Four-legged friends are welcome in San Luis Obispo. Choose from more than 110 vacation rentals for guests traveling with pets.

  • Are there San Luis Obispo vacation rentals on Airbnb with pools?

    Yes! Dive into the perfect getaway at one of over 30 vacation homes with pools in San Luis Obispo, available on Airbnb. Make a splash and soak up the sun in style!

  • How much does it cost to stay in apartment rentals in San Luis Obispo?

    Experience the best of San Luis Obispo with our apartment rentals, starting at about $50 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Are there family-friendly vacation rentals in San Luis Obispo?

    San Luis Obispo has more than 170 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.

  • Do house rentals in San Luis Obispo have a bbq area?

    Absolutely! We offer over 50 house rentals with a bbq area in San Luis Obispo. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in San Luis Obispo have a gym?

    Absolutely! We offer over 10 house rentals with a gym in San Luis Obispo. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in San Luis Obispo have self check-in?

    Absolutely! We offer over 60 house rentals with self check-in in San Luis Obispo. Enjoy a tailored experience with all the comforts you desire.

  • What are the most popular amenities for House Rentals in San Luis Obispo?

    Enhance your stay in our House Rentals with the most popular amenities: over 50 homes with a bbq area, over 10 homes with a gym, over 60 homes with self check-in, and more. Indulge in the ultimate retreat, tailored to your preferences.

Destinations to explore