Pet-friendly vacation rentals in Jefferson County

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in Jefferson County

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Top guest favorite

Tiny home in Pacific

4.96 out of 5 average rating, 267 reviews

Route 66 Railroad Shanty, a cozy artsy small space

This 536 s.f. house, believed to have once been a sleeping shanty for railroad crews switching shifts for the night. Fully renovated and updated in 2021 by a local artist, you will find custom metal art throughout, granite countertops and a very warm cabin feel featuring a kitchen and bathroom finished with locally sourced Missouri dark red cedar, 10 minutes from six flags, Purina farms 15 min from hidden valley and 45 min from downtown this place is in a great location and will not disappoint!

Guest favorite

Home in Pacific

4.93 out of 5 average rating, 156 reviews

Pacific Palace, super unique!

The Pacific Palace is unlike any other Airbnb! Located in the heart of downtown Pacific, Missouri - only 2 minutes from Highway 44 and 10 minutes from Purina. This house is an incredible one of a kind treasure with lots of unique features including: outdoor gazebo, fish pond, all original cedar interior design, two second story balconies, two large bat tubs (one located in the main bedroom) and so much more!!! Private parking and a gate for added privacy. Just minutes from Six Flags. Book today

Guest favorite

Cabin in Bonne Terre

4.86 out of 5 average rating, 109 reviews

Hand Built Log Cabin

This cabin was completed in 1940 by previous owner's grandmother with only the help of her horses. The wood was cut from the property. Originally it had no electric or plumbing, we updated it more in 2021 keeping as much original as possible. Rustic cabin has 2 bedrooms, 1 bathroom with walk-in shower only, washer and dryer, full eat in kitchen and living room. On site you can relax watching horses, mini horses, goats, chickens & ducks as well as wild life. You can feed and pet the 🐐 goats.

Guest favorite

Guesthouse in Barnhart

4.92 out of 5 average rating, 25 reviews

Summit View Guest House

Nestled away from the all the hustle and bustle yet conveniently close to everything. Here at Summit View is like your own little oasis 10 minutes from town. Our space is a rustic themed guesthouse retreat located above our detached garage overlooking the shared pool, patio and outdoor kitchen/ bbq area. In the early mornings and afternoons you may spot deer grazing in the backyard. Summit View is pet friendly! We have 2 small dogs Penny & Merle. Both are friendly and play together outside.

Guest favorite

Cabin in Pacific

4.88 out of 5 average rating, 17 reviews

Charming cabin/outstanding view

Unique and tranquil getaway. Charming cabin on almost 4 acres of 19 acre lake development. Relax on deck enjoying the peace & quiet. Deer frequent the property. Bedroom has queen bed plus a bunk above and there is a full sized Murphy bed in great room. Plenty of firewood available. Six Flags, Hidden Valley, Purina Farms, Shaw Nature Preserve are just a short drive. Enjoy hiking at 3 close by conservation areas & several state parks. Owner will consider selling - ask for details.

Top guest favorite

Cabin in Festus

4.99 out of 5 average rating, 67 reviews

Relaxing Log Cabin Getaway on 20 Acres

Stunning 1800s log cabin located 40 minutes from St. Louis. This is the perfect holiday for groups who love a private outdoor setting. The house includes three family areas, WiFi, and a high-end kitchen. Outside, find a fire-pit, scenic porches for relaxing, and a kids playhouse. The Rec Room above the garage features a theater area, ping pong, pop-a-shot, and foosball. The property is 20 acres and offers fields for playing games, hiking trails for walking, and a creek for exploring.

Guest favorite

Home in Dittmer

4.95 out of 5 average rating, 503 reviews

Honeymoon Suite at Camp Skullbone In The Woods

Experience a romantic, quiet, and cozy chalet designed for two! This charming retreat features vintage décor and all the modern amenities you need for a comfortable stay. Unwind indoors by kicking back and watching a movie, surfing the web, curling up with a good book or a friendly board game, or sharing a drink with that special someone. In the evening, relax on the cozy deck under the stars, basking in the warm glow of the gas fire pit or unwinding in the inviting private hot tub!

Superhost

Farm stay in Hillsboro

4.92 out of 5 average rating, 179 reviews

Shagbark Hickory Cottage (Hot tub & Sauna)

Take it easy at this unique and tranquil getaway. Enjoy a detox in our handcrafted sauna, or take a soak in the hot tub under the stars! Full kitchen, bathR w/claw foot, & screened in porch. It’s very private, with land to explore. Take a stroll to the pond or creek where you will see a little piece of history, or possibly enjoy a visit from our sweet cows. Close to La Chance winery, Desoto town, Big River access points, valley view glades, & Washington state park.

Guest favorite

Treehouse in Dittmer

4.81 out of 5 average rating, 141 reviews

The Den at Dittmer Hollow

Newly Updated** Enjoy the lovely setting of this romantic spot in nature, with a semi-primitive, modern cozy secluded treehouse in the woods! Explore 10 acres or wind down on the deck before relaxing in the *NEW* hot tub. The cabin inside has a very minimalistic design featuring on the first floor an electric fireplace, air conditioner, table, refrigerator, leather futon couch, kitchenette with a hand crank water pump sink, axe throwing and porta-potty bathroom.

Superhost

Townhouse in Barnhart

4.85 out of 5 average rating, 78 reviews

Cozy town house - fenced backyard - Barnhart

Relax and recharge with the whole family at this peaceful getaway, tucked away in a safe and quiet neighborhood. With three cozy, thoughtfully decorated bedrooms, a fully equipped kitchen, and a fenced backyard perfect for unwinding, this home offers everything you need for a comfortable and restful stay. Though not in the heart of the city, you'll enjoy easy access to major highways—making it simple to explore all that St. Louis has to offer.

Guest favorite

Home in Eureka

4.94 out of 5 average rating, 16 reviews

Garden of Life in Eureka 73

* Fresh air surrounded by nature and wildlife * Fully renovated new house * Relax with the large family or group at this peaceful and comfortable home * WIFI, Smart TV, Washer/Dryer, Solo stove fire pit * Sufficient parking space * Very safe neighborhood (2 minutes away from fire station) Grocery Store (Price Chopper or Schnucks) ~ 10 minutes away Walgreens, 6 minutes Fox Run Golf Club, 3 minutes Six Flags, 15 minutes Highway 44, 10 minutes

Guest favorite

Cottage in Eureka

4.92 out of 5 average rating, 316 reviews

Beautiful Cottage on Large Private Lot

This lovely rural cottage is nestled back in the woods on its very own private acre of land. It offers guests a beautiful getaway experience while at the same time being just a 7 minute drive from downtown Eureka with its many delicious restaurants and adorable boutiques. Six Flags is a brief 10 minute drive, and Purina Farms is 15. We have ample parking for multiple vehicles and a completely fenced in yard great for 4 legged friends.