Vacation rentals in Defiance

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Top-rated vacation rentals in Defiance

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Guest favorite

A scenic view of the home's private shoreline, featuring a spacious patio area with multiple seating arrangements. A charming stone walkway leads to the composite dock, surrounded by lush greenery and rocky landscaping, enhancing the natural setting near Lake Wren.

Chalet in Wright City

5 out of 5 average rating, 11 reviews

On The Rocks by Innsbrook Vacations!

DanielRating, 5 stars4 weeks ago

Innsbrook is one of the nicest private resorts in the area. This particular stay is very accommodating for larger families or maybe two small families looking for a lake vacation. the hot tub with the TV under the deck was perfect for us! The golf course is immaculate! Dane was a great host and very responsive!

Guest favorite

Home in Hermann

4.92 out of 5 average rating, 167 reviews

French Hill- Amazing location with the best views!

AlyssaRating, 5 stars5 months ago

Our group of 8 had a great stay here! The house is so charming and beautifully decorated, it was very clean, and the beds were SO comfortable. The house is in a great location and the trolley came and picked us up. We would definitely stay here again!

Superhost

A path leads to the cottage, surrounded by lush greenery and tall trees. The structure features a combination of large windows and a side deck, offering a welcoming entry point into the peaceful wooded setting.

Cottage in Innsbrook

4.88 out of 5 average rating, 101 reviews

Dock & Resort Perks: Quiet Lakefront Cottage

JanetRating, 5 stars3 weeks ago

What a postcard! Picturesque location where the sounds of nature take over and the bustle of the word recedes. WONDERFULLY comfortable king bed in the master was so appreciated. Everything for which we’d hoped, plus gracious, helpful and attentive hosts made our quick stay a memorable one. (We’re now considering relocating- Innsbrook is magical!)

Guest favorite

A panoramic view showcases the tranquil riverfront, bordered by lush greenery. The sunlit deck features a dining table surrounded by comfortable chairs, while a fire pit is positioned nearby. In the distance, boats glide along the water, enhancing the serene atmosphere.

Home in Grafton

4.97 out of 5 average rating, 155 reviews

Grafton Getaway@Riverhouse (a waterfront property)

EricaRating, 5 stars1 week ago

Where to begin…from the moment my sister and our spouses selected this house for our meet in the middle of our states visit Brandon was quick to reach out and ensure everything was perfect for our visit! The location is perfect…right on the river and walkable to restaurants, winery, and shops. The house had so many fun extra’s that we really enjoyed! The plethora of games, record player/great albums, foosball, putting green and much more. We stayed up late playing records. Outside was a beautiful deck with a great view of the river, lots of seating and a fire pit with wood/lighter fluid to start a fire quickly. We had the best time just sitting around the fire and enjoying the river and the beautiful evening. The house is equipped with EVERYTHING you could possibly need. The house was super cute/cozy with comfy beds. We loved that we had several choices for dining just a short walk away. The bike trail behind house was great! We love the house, hospitality and town. We will return!

Top guest favorite

A sunlit screened-in porch features white wicker chairs with purple cushions positioned on polished wooden floors. Two hanging ferns provide greenery above, while a wooden swing adds a cozy seating area. Large windows allow for ample natural light and a view of the outside.

Home in Grafton

5 out of 5 average rating, 23 reviews

Stay In A Piece Of History

ElizabethRating, 5 stars1 week ago

Had a wonderful time in downtown Grafton for my daughter’s 21st birthday. The house is in a great location for walking distance to all attractions, restaurants, bars, shops and more. It was nice to not have to drive anywhere after celebrating her birthday! We will definitely be back!

Top guest favorite

The kitchen displays modern amenities, including a stainless steel gas stove and microwave. White cabinetry provides storage, complemented by a drawer for utensils. A window allows natural light, while decorative letters spell 'EAT' on the wall, adding a subtle touch to the space.

Home in South Hampton

5 out of 5 average rating, 42 reviews

Blair's Amazing House Sleeps 10 - 5 Beds - 2 Bath

HowardRating, 5 stars3 weeks ago

The house is well laid out, clean, and in a nice neighborhood. The location is convenient, safe, and quiet. The owner was responsive and flexible. While there is a garage, we never used it as there was always on-street parking right in front of the house. Everyone in our party thought it was a great choice!

Superhost

An outdoor patio area features two blue Adirondack chairs positioned on a wooden deck. The view includes a green lawn and surrounding trees, providing a sense of tranquility. A low fence adds definition to the space, enhancing its openness.

Apartment in Waterloo

4.78 out of 5 average rating, 69 reviews

Waterloo. 1 block from the downtown City Square.

MosesRating, 5 stars2 weeks ago

I've stayed here multiple times and it’s exactly as advertised: clean, peaceful, and comfortable. The apartment is well-stocked, the TVs are great, and having a washer/dryer in-unit is a huge bonus. It's a perfect spot if you're looking for a quiet place to relax near downtown Waterloo. Hosts are reliable and clearly care about making the stay easy and smooth. Highly recommend!

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Popular amenities for Defiance vacation rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Stay near Defiance's top sights

Montelle Winery10 locals recommend

Historic Daniel Boone Home6 locals recommend

Chandler Hill Vineyards5 locals recommend

Klondike Park3 locals recommend

Noboleis Vineyards4 locals recommend

Quarry Wine Garden3 locals recommend

Other great vacation rentals in Defiance

Guest favorite

A sunlit yard features a circular pool with clear blue water, complemented by a green inflatable and surrounded by lush greenery. Comfortable seating areas with striped cushions and vibrant umbrellas provide shaded spots nearby, creating an inviting outdoor space for relaxation.

Home in St. Louis

5 out of 5 average rating, 5 reviews

home away from home

AshleyRating, 5 stars8 months ago

Took a mini vacay to St Louis with my mom & the kiddos. 3 adults & 2 children had plenty of space for sleeping. The pool & hot tub were so relaxing. It felt so homey. We were offered fresh produce from the garden. Lots of pots & pans if you like to cook while traveling. The bar was nice if you like to relax with a drink. Everyone loved the Pac-Man machine! Tons of at home amenities like streaming channels, coffee maker, potato chips, toys for the kiddos, giant Jenga set, etc. Private & safe location. Only 20-30 mins driving to the heart of St Louis. We really enjoyed our weekend and would recommend this home to anyone needing a family spot to relax.

Guest favorite

Chalet in Innsbrook

4.96 out of 5 average rating, 79 reviews

Beautiful 5 Bedroom Lakefront Chalet with Beach

JonathanRating, 5 stars1 week ago

Great Lake house for a small retreat. We had a fantastic time. Matt is a stellar host. No hesitations coming back with my fam or for our next work retreat.

Guest favorite

A fenced yard is featured, showcasing a blend of wooden panels in various tones. Flowering plants line the edge, with vibrant blooms among greenery. A putting green area is visible in the foreground, accompanied by a paved pathway leading to outdoor seating.

Home in St. Louis

4.89 out of 5 average rating, 208 reviews

Home away from Home St. Louis Cnty Ladue Schools

RichardRating, 5 stars3 weeks ago

the place was great and was in the perfect location for us. Lisa was so nice, and we felt very comfortable. I would recommend staying here to anyone.

Guest favorite

A charming house is set against a backdrop of vibrant green trees, situated by a serene pond. A spacious porch with white railings provides a welcoming entrance. A small dock extends into the water, enhancing the tranquil outdoor setting.

Home in Owensville

4.94 out of 5 average rating, 31 reviews

Post Oak Chaise

HeatherRating, 5 stars2 days ago

This is our third stay, and we will return. The property is beautiful and peaceful, and lots of room for our dogs to run (and swim!). We love birdwatching and feeding the fish and turtles in the pond. We had a lot of rain this time around, but the place was well-stocked with games and puzzles. The furniture is very comfortable and love the new beds in the second bedroom.

Top guest favorite

A modern kitchen space features exposed brick walls and warm wooden flooring. A rustic dining table with metal chairs is positioned in the center. Stainless steel appliances and cabinetry are visible, along with decorative items on shelves, creating a functional and inviting atmosphere.

Home in Hermann

5 out of 5 average rating, 158 reviews

Studio 1892 Guesthouse-New! Downtown Location!

TrishinaRating, 5 stars1 week ago

Studio 1892 Guesthouse is absolutely adorable and the perfect place for our girls weekend. From the lovely 3 seasons room to the well appointed kitchen there was so much space for our group of 6. The linens on the beds were so comfortable, we even checked the brand! We loved the fire pit and seating outside. We ran out of propane the first night, but Karen supplied more for night 2. Not to mention, the location was incredible! It walking distance to everything downtown yet still quiet. We will stay there next time we spend the weekend in Hermann.

Superhost

A wooden deck extends alongside a serene river, surrounded by lush green trees. The water reflects the greenery above, providing a calming natural view. Soft sunlight filters through the leaves, creating a peaceful atmosphere.

Home in House Springs

4.73 out of 5 average rating, 62 reviews

Entire House in House Springs

ShirleyRating, 5 stars3 weeks ago

Our stay here was great! Dzenad was very responsive with any questions I had. It is so peaceful with the river practically in the backyard. I DEFINITELY recommend staying there if you get the chance.

Guest favorite

A modern kitchen features crisp white cabinetry and stainless steel appliances. A large island with bar seating for four is illuminated by pendant lights. Natural light enters through a window by the dining area, enhancing the open and functional design.

Home in St. Louis

5 out of 5 average rating, 40 reviews

Bright Urban Comfort | JZ Vacation Rentals

AmandaRating, 5 stars1 week ago

This house was perfect for a larger group! We felt like we had a lot of space even with 12 people in the house! The location was perfect, as it only took 7-9 minutes to get to most tourist attractions. We appreciated how clean the house was as well! The house is exactly as it shows in the pictures! We would definitely stay here again on our next trip!

Guest favorite

A modern kitchen area features dark wooden cabinets and a granite countertop. An espresso machine is positioned beside a carousel of coffee pods. Stainless steel appliances are visible in the background, complemented by a vibrant painting of colorful umbrellas on the wall.

Home in O'Fallon

5 out of 5 average rating, 11 reviews

Quaint and Cozy Hamlet

DanielleRating, 5 stars2 days ago

place was squeaky clean and host was responsive to any questions. would stay at this location again!

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Quick stats about vacation rentals in Defiance

Total rentals
10 properties
Nightly prices starting at
$70 before taxes and fees
Total number of reviews
340 reviews
Wifi availability
10 properties include access to wifi
Popular amenities
Kitchen, Wifi, and Pool
Local attractions
Defiance Roadhouse, Defiance Ridge Vineyards, and Good News Brewing Company Defiance

Vacation rentals in Defiance

Top-rated vacation rentals in Defiance

Vacation rentals for every style

Popular amenities for Defiance vacation rentals

Stay near Defiance's top sights

Other great vacation rentals in Defiance

Quick stats about vacation rentals in Defiance

Total rentals

Nightly prices starting at

Total number of reviews

Wifi availability

Popular amenities

Local attractions

Destinations to explore