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Santo Domingo villas

Book unique villas, vacation rentals, and more on Airbnb

Top-rated villas in Santo Domingo

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

Villa in Gazcue
✔️ 20-PAX VILLA | POOL | 8-BEDROOM | ZONA COLONIAL
This Completely Renovated and Updated Luxury Colonial Mansion from the 1920's is located in the City Center of Santo Domingo at Walking Distance from Major Highlights. The Villa comes with 8 Deluxe Rooms, all with Private Bathroom, AC, TV, WIFI and total space for up to 20 Guests! The Villa comes with a Spacious living room with a bar, lounge area, large TV, Soundsystem. The spacious terrace comes with a Private Pool, Barbecue & Lounge Area, and indoor private parking. Close to Entertainment!
$683 per night
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Villa in Santo Domingo Este
Beautiful family villa 👩‍👩‍👦‍👦 in the Americas .
Have fun with the whole family at this place with style and elegance !! It has good amenities to enjoy TVs such as: pool , shower area, gazebos area, basketball court, family room , 4 comfortable luxury rooms, living room , dining room, air in all rooms, wifi, tv, garden, hot and cold kitchen and BBQ. Location 👇https://g.co/kgs/zkSyzf
$321 per night
Villa in El Cacique
Beautiful City Center House (Private jacuzzi).
Completo primer nivel (en casa de 2 niveles). Haz tus vacaciones placenteras en el centro de la ciudad, escucha el cantar de los pájaros en las mañanas, amortigua el calor con nuestro jacuzzi y las noches haz BBQ en el patio. Primer nivel totalmente privado, pensado para el disfrute y descanso de nuestros huéspedes.
$129 per night

Stay near Santo Domingo's top sights

Photo of Sambil
Sambil122 locals recommend
Photo of Ágora Mall
Ágora Mall211 locals recommend
Photo of Malecón Santo Domingo
Malecón Santo Domingo103 locals recommend
Photo of Bella Vista Mall
Bella Vista Mall86 locals recommend
Photo of BlueMall Santo Domingo
BlueMall Santo Domingo231 locals recommend
Photo of Centro Olímpico Juan Pablo Duarte
Centro Olímpico Juan Pablo Duarte12 locals recommend

Santo Domingo apartments

Rental unit in Piantini
HOME RELAXLIVING REGATTAII PIANTINICITYCENTER 206
$55 per night
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Rental unit in Santo Domingo
Exclusive n’ Fancy Place @Piantini Santo Domingo
$63 per night
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Rental unit in Julieta Morales
Luxury Downtown Apartment, Great Views, Shared Gym & Rooftop
$79 per night
PLUS
Rental unit in Piantini
Centric Exquisite 1BR in Piantini - WeHost
$68 per night
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Rental unit in Santo Domingo
Suite King Bed Downtown SDQ - Apt. 604
$55 per night
Rental unit in Julieta Morales
★★★★★ | STAR WARS THEME STUDIO | BEST LOCATION
$59 per night
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Rental unit in Ensanche Quisqueya
Beautiful and Luxury apartment 1BR pool&gym - 505
$54 per night
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Rental unit in Julieta Morales
Elegant Apartment In The Heart Of Sto. Dgo.
$51 per night
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Rental unit in Piantini
Apt Centrico Piantini with Parking
$50 per night
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Rental unit in Piantini
The🌇City〽️ Spot📍@DowntownSD ➕Gym➕WIFI➕24/7Check-in
$64 per night
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Rental unit in Julieta Morales
Modern City Center Studio + Pool & Gym
$59 per night
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Rental unit in Esperilla
Luxury Place In the City, Pool, Gym, King Bed, NEW
$65 per night

Santo Domingo vacation rentals

Condo in Piantini
Premium Apt, Seaview social area pool ,Piantini
$72 per night
Condo in Piantini
New-PIANTINI-Kingbed-POOL-wifi-GYM
$72 per night
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Rental unit in Santo Domingo
Lovely 1BR Rental Unit in Naco -RELAX- | Renty 703
$38 per night
Condo in Piantini
Luxury 15th F 1BD Suite Downtown Piantini
$56 per night
Condo in Julieta Morales
MODERN ONE BEDROOM APARTMENT NEAR CITY CENTER
$59 per night
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Condo in Piantini
Luxury Aparment, City center, 14th Floor Piantini
$65 per night
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Condo in Piantini
Unbeatably close to the best of Santo Domingo
$68 per night
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Rental unit in Julieta Morales
Modern Apt. near Blue Mall W/ WorkS, GYM & POOL
$56 per night
Rental unit in Julieta Morales
LUXURY AND MODERN 1 BR APT. | BEST LOCATION | POOL
$61 per night
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Rental unit in Piantini
Home RelaxLiving RegattaII PIANTINICITYCENTER 501
$55 per night
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Condo in Santo Domingo
—HugeBalcony— Kingbed | Pool | PingPong | FastWiFi
$62 per night
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Condo in Piantini
🥂Close to everything📍Netflix🍿A/C🥶WiFi⚡️Garage🚗 DT🌆
$48 per night
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Santo Domingo houses

Private room in Los Prados
S2FreeComfortBed &BreakfastFull WifiNetflixFree
$24 per night
Home in Los Prados
D2Free:DesayunoFullWifiNetflix+ComfortBed.
$34 per night
Private room in Santo Domingo
Full room with private bathroom in colonial area +
$17 per night
Private room in Gazcue
ZONA COLONIAL*walking distance B
$24 per night
Private room in Santo Domingo
house full of life, tranquility and joy. Room (A)
$16 per night
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Home in Santo Domingo
🛁 🌈My House RD # 2🛁 JACUZZI where you are a VIP guest
$49 per night
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Private room in Zona Colonial
Colonial Beach House - Room "Macao Beach"
$52 per night
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Home in Santo Domingo
Cozy, central, well-equipped
$30 per night
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Private room in Zona Colonial
Colonial zone+Shared Pool+Wi-fi (Taino)
$32 per night
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Private room in Zona Colonial
Casa Donderis Colonial - Blue Room
$35 per night
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Private room in Zona Colonial
Recycled room in zona colonial R2
$14 per night
Home in Zona Colonial
Beautiful Colonial House with terrace and patio
$55 per night
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Your guide to Santo Domingo

All About Santo Domingo

Santo Domingo sits on the southern shore of the Dominican Republic and is one of the oldest cities in the Caribbean. The cobblestone streets and 16th-century buildings illustrate this capital city’s long history. As you wander the narrow lanes, you’ll take in vibrant town squares and old palaces now home to fascinating museums — such as Alcázar de Colón, part of the Ciudad Colonial UNESCO World Heritage Site. One of the oldest cathedrals in the Americas, the 16th-century Catedral Primada de América, stands in a lively, leafy plaza amid people seated on shaded benches or enjoying coffee in the nearby cafe.

The Malecón de Santo Domingo promenade provides a fantastic spot to take in the sweeping views of the Caribbean Sea while enjoying a cold beer or a bite at one of the restaurants and bars on the waterfront. For a small taste of the country’s natural scenery, you can head out to Three Eyes National Park, with its three turquoise lakes, or the National Botanical Gardens, brimming with indigenous plants and peaceful green spaces.


When is the best time to stay in a vacation rental in Santo Domingo?

As a tropical destination, Santo Domingo has warm weather all year round. It also experiences a dry season from around November to March, which is a lovely time to explore some of the Dominican Republic’s spectacular beaches. The dry season is also the busiest time of the year, especially during Carnival, which sees colorful parades and nationwide celebrations for the month of February, culminating on Independence Day on February 27. The historic center of town can get crowded during this time, which is good to keep in mind when you’re booking your Santo Domingo apartment rental. Visitor numbers start to thin out in April and May as the rainy season approaches, which is a pleasant time for exploring the city’s narrow streets. The rainy season lasts from May to November, with short bursts of rainfall followed by hours of sunshine.


What are the top things to do in Santo Domingo?

National Botanic Garden

One of the largest botanical gardens in the Caribbean, this sprawling complex showcases the diversity of the Dominican Republic’s various ecosystems. As you walk through the central square, you can admire ponds full of aquatic plants and colorful fish and check out the massive floral clock. At the Herbarium, you’ll learn about the native plants used in traditional medicine.

The Three Eyes National Park

Just a 10-minute drive from Santo Domingo, this spectacular nature reserve is home to a complex open-air limestone cave system. Its three crystal-clear turquoise lakes — the Three Eyes — are fed by an underground river and surrounded by dramatic stalactites and stalagmites. Lush forests envelop the caves, and if you are lucky, you may spot fish, turtles, or bats while you are there.

Calle Las Damas

Built in 1502, this cobblestone street was one of the first paved streets in the Americas and is lined with some of Santo Domingo’s oldest buildings, including the Fortaleza Ozama, one of the oldest forts in the Americas and a World Heritage Site. “The Ladies Street” is named after the gracious women who strolled along the street during the evenings.