
House vacation rentals in Santo Domingo
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Top-rated house rentals in Santo Domingo
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Casa Serena: cozy, modern, spacious and peaceful
Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.

Luxury Penthouse With Jacuzzi
Come and decompress into your private oasis retreat. This penthouse features 4 bedroom, 3 bath, fully equipped kitchen, and calming jacuzzi. Immerse yourself in panoramic views from rooftop terrace. We are located in one of the best residential area in Santo Domingo Este. Just 15 min. from Las America International Airport, and 20 min. from beaches. Nearby you will also find great restaurants, bars, supermarket, shopping centers and pharmacies. Book now for the utmost Dominican Experience!!

Colorful Caribbean house in the Zona Colonial
Enjoy a marvelous stay at this gorgeous, colorful and spacious home at the Zona Colonial. Light, airy rooms and amazing private outdoors create a unique caribbean flair. Relax in the tropical garden...refresh yourself with a dip into the tiny pool…dine under the stars or enjoy the amazing view of the San Francisco monastery ruins from the balcony. The famous Plaza de España is a few steps away and all the historical sites, museums, restaurants, cafés and bars are within easy walking distance.

Casa Grullon - Loft. Comfort & ancient beauty meet
Perfect, lovely & charming loft to explore La Zona. Transport yourself to another era staying at Casa Grullon Loft (1 master bedroom, 1 open bedroom, 1 bathroom) dating back to the 1700s, offers a unique chance to experience colonial charm without sacrificing modern conveniences (like air-conditioning). Stay here and discover La Zona just by walking! everything is within walking distance (top restaurants are just 1 min away!), making the location perfect to explore the best of Santo Domingo.

casa bella 3 camas 1 king + 2 twin airport 15min.
Relájate en este espacio tranquilo,elegante y seguro aeropuerto (15 minutos) playas ,calles principales Supermercados cerca (zona súper tranquila segura y muy confortable ) 1–incluimos servicio de lavado y secado 2–wifi 3–Tv Smart 55 sala y 65 hab principal 4–puerta principal inteligente con clave 5–muebles en leather 6– cama principal king size 7–aire acondicionado en la principal 8–parqueo techado y cerrado 9–inversor de Luz 24 horas incluido Soy súper atento con mis huéspedes

Beautiful modern Colonial House with terrace
Beautiful colonial house located in the historic center of Santo Domingo. The house is made up of two studio-apartments, which are rented separately. Each apartment has a bedroom, a bathroom, a living room and a kitchenette to prepare breakfasts and snacks. The two apartments share three areas: a fully equipped kitchen, the patio and the upper terrace. The main historical attractions of the first city of the New World are a five-minute walk from the house.

Stunning villa in Zona Colonial
Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.

Cozy, central and well-equipped place
We are located in a central and quiet part of the city, with access to 27 de Febrero, Máximo Gómez, and Jhon F. Kennedy avenues. Nearby are the Ibero-American University (Uníbe), Zambil shopping center, Banco Popular Dominicano Tower, as well as pharmacies and health centers. The apartment is located on the first floor, with independent access, parking, and an electric gate. It has a cable system, high-speed WiFi, and an inverter.

La Casita de Gazcue Bright C Suite
This simple but charming accommodation offers you a relaxing experience in a privileged location: just a 12-minute walk from the historic Colonial Zone and three blocks from the iconic Malecón, where you can enjoy ocean views, restaurants, and nightlife. Ideal for relaxing without going far, our space combines serenity with quick access to the main tourist, cultural and gastronomic attractions. Your comfort is our priority.

Cozy little house in the heart of the Colonial Zone
A cozy 2-bedroom house for 4 people, located in the heart of the Colonial Zone in Santo Domingo, within walking distance of all cultural and tourist attractions. It has 2 comfortable bedrooms and a study with a sofa bed; 2 bathrooms, a nice living room, large dining room, equipped kitchen and a beautiful inner courtyard. Wonderful for vacations and cultural trips, ideal for couples, families, friends, and business travelers.

Charming Old City Corner House
This charming 2 bedroom corner house is located in the walled colonial city of Santo Domingo. It’s only a few steps away from historical attractions, museums, restaurants, coffee shops, bars, souvenir shops, bakeries, supermarket and lovely squares. The beautiful covered terrace, overlooking the rooftops of the old town with living area, hammock and BBQ is perfect for a relaxing afternoon or evening.

Your 2BR House + Terrace in the Colonial Zone
Feel the history in this authentic Colonial house from the XVI century with all the modern amenities you will need to make your trip unforgettable. Enjoy a walk to history in the oldest city of America. Visit impressive cultural sites, exquisite restaurants and bars. Have fun in a great night atmosphere. In just minutes you can be in the ocean shore ( malecon ) or in the Colonial promenade.
Popular amenities for Santo Domingo house rentals
House rentals with a pool

Cheerful 4 bedroom home with pool and parking

House for groups with a pool SDE

PrivatePool - BBQ - Terrace - Excelent for Big Fam

Experience Ultimate Comfort | 4BR Home

Royal Villa with a swimming pool in Villa Mella SD Norte.

Casa Aló:Private house with jacuzzi in the Capital

Family Villa with Pool

Villa Marayath!To enjoy with all families & friend
Weekly house rentals

Luxury, Classy Private House In Santo Domingo

Comfortable house in Sto Dgo Este

Modern Comfort-3BR House w/ Patio- near Airport

Sweet 🏡 home

Modern House with Terrace

Zona Colonial Large Room, Private Bath & Entrance

House in Santo Domingo

Cozy place in Santo Domingo Este.
Private house rentals

Large Colonial House • Central • Spacious • Comfortable • Safe

House near the airport, queen bed + sofa bed.

LJC Stay

COZY 3-BED HOUSE FIRST Floor KING Bed

Casa de Bendición, cerca Coral Mall, AU San Isidro

BRAND NEW 1Bdr Apt in the Heart of SDQ!

Large studio apartment with pool and sea in S.D.

D5 Free: Desayuno Full Wifi Netflix + Comfort Bed..
When is the best time to visit Santo Domingo?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | € 40 | € 39 | € 43 | € 43 | € 43 | € 43 | € 43 | € 43 | € 43 | € 41 | € 43 | € 43 |
| Avg. temp | 26°C | 26°C | 26°C | 27°C | 27°C | 28°C | 28°C | 28°C | 28°C | 28°C | 27°C | 26°C |
Quick stats about house rentals in Santo Domingo

Total vacation rentals
Explore 490 vacation rentals in Santo Domingo

Nightly prices starting at
Santo Domingo vacation rentals start at € 9 per night before taxes and fees

Verified guest reviews
Over 11,640 verified reviews to help you choose

Family-friendly vacation rentals
200 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 120 rentals that welcome pets

Vacation rentals with a pool
90 properties feature pools

Rentals with dedicated workspaces
180 properties have a dedicated workspace

Wi-Fi availability
450 of Santo Domingo vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santo Domingo rentals

4.6 Average rating
Santo Domingo stays receive an average rating of 4.6 out of 5 from guests
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- Playa Hemingway
- Playa Nueva Romana
- Ciudad Juan Bosch
- Metro Country Club
- Playa Guayacanes
- Malecón
- Plaza De La Cultura
- Enriquillo Park
- Centro Olímpico Juan Pablo Duarte
- Santo Domingo Country Club
- Teatro Nacional Eduardo Brito
- Downtown Center
- Félix Sánchez Olympic Stadium
- Dr. Rafael Ma. Moscoso National Botanical Garden
- Cotubanamá National Park
- Colonial City
- Blue Mall
- Bella Vista Mall
- Agora Mall
- Galería 360
- Casa Adefra
- Megacentro
- Malecón de San Pedro de Macorís
- Parque Iberoamerica
- Things to do Santo Domingo
- Food and drink Santo Domingo
- Nature and outdoors Santo Domingo
- Things to do Distrito Nacional
- Nature and outdoors Distrito Nacional
- Food and drink Distrito Nacional
- Things to do Dominican Republic
- Art and culture Dominican Republic
- Tours Dominican Republic
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- Entertainment Dominican Republic
- Sports activities Dominican Republic
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- Nature and outdoors Dominican Republic
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
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- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes




