
Guesthouse vacation rentals in Santo Domingo
Find and book unique guesthouse rentals on Airbnb
Quick stats about guesthouse rentals in Santo Domingo

Total vacation rentals
Explore 70 vacation rentals in Santo Domingo

Nightly prices starting at
Santo Domingo vacation rentals start at $10 per night before taxes and fees

Verified guest reviews
Over 1,270 verified reviews to help you choose

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Rentals with dedicated workspaces
50 properties have a dedicated workspace

Wi-Fi availability
70 of Santo Domingo vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santo Domingo rentals
Top-rated guesthouse rentals in Santo Domingo
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Private Cozy Apartment Studio
One bedroom studio, centrally located in the heart of El Millón, Santo Domingo, where comfort, convenience, and warm space offers the intimate feel of a family home, featuring: A private entrance for your complete privacy. Dedicated parking for your convenience and peace of mind. Whether you're visiting for leisure or business, our studio is thoughtfully designed to meet your needs. Remote workers will appreciate the high-speed internet, ensuring uninterrupted connectivity throughout your stay.

Centrally located and unique colonial-style studio
Unique space in a 1930s house, with rustic-industrial elements. Elegant room with original hydraulic floor. Large patio with perimeter fence and electric gate. Centrally located, less than 3 kilometers from the Colonial Zone, 2.5 kilometers from the Central Polygon. Hospital, Laundry, Pharmacy, Malecon 1-2 blocks away. 500-600 meters from 2 subway stations, close to museums and restaurants. Updated technology. Smart speaker. Wi-Fi. TV with YouTube, Netflix, Prime Video. Double bed (full size).

VillaMella Oasis 2bedroom2bathroom Patio Hot Water
Welcome to your Oasis in Villa Mella. Relax in comfort and luxury with a second-floor-level, 2 queen beds, 2 private baths, and a fold-out sofa. Enjoy A/C, hot water, fast WIFI, and 3 Roku TVs with Netflix. Secure smart lock entry and 24/7 on-site staff that will ensure peace of mind. Just a 5-minute walk from the Gregorio Gilbert Metro station. Bring the whole family to this great place with lots of room for fun. Need a driver? We've got you covered. Let us melt your stress away! Book now!

Cozy 2 BR with BBQ
This 2 bedroom apartment with BBQ private area is truly bright and cozy . It takes 25 minutes to arrive from the airport. The spacious master bedroom has a queen size bed and the very bright single room have two twins bed. You have discount with our car rental services with airport pick-up. The neighborhood is very safe, is private with access control and very clean, there are many restaurants nearby many bars, gyms, movie theaters, shopping malls . The neighbours are lovely and quiet.

Nido del patio, 40 min to Bocachica beach 5 center
You will have the entire apartment just for you. Enjoy the tranquility that the area offers, an ideal place to rest and work, and a strategic point to travel to places of interest You are responsible for cleaning the accommodation during your stay. It is delivered clean. If you need it, you can request cleaning service at an additional charge. The patio is rarely shared. Usually, only you will enjoy the patio. The host is in charge of cleaning the patio area.

Cozy apartment for work / holidays.
Comfortable apartment, on second level, with private parking, ideal for holiday trips, congresses, jobs and others. Close to shopping centers, Recreational park, clinics, universities; 25 minutes from the colonial area. Located in downtown area of the city, in the urbanization El Millón del Distrito Nacional. Peaceful, residential place with access to the main roads of the city.

Near U.S. Embassy – Visa Appointments – Guest House – Pool
You no longer need to leave the city to feel in the mountains, this is an independent 1 bed 1 bath Guest House in a closed residence with a 10-meter pool shared with the Hosts. With a Coway potable water filter. Supermarkets, Cinema, Shops, and Hair Salon nearby. A few minutes from the center of Santo Domingo and 1.8 km from the American Embassy.

Your little corner of peace in SDO
Kick back and relax in this calm, stylish space. “Tu rinconcito de Paz” is an oasis in the middle of the city rush, take some fresh air in our outdoor Gazebo area, enjoy the privacy and security of our small but cozy house. Commercial centers as Carrefour and numerous restaurants are located at 8 minutes away from our spot.

U.S. Embassy Suites
Have fun with the whole family at this stylish place while taking it easy at a unique and tranquil getaway. Perfect while on the go or for appointments at the U.S. embassy. Guesthouse comes included with access to an olympic style pool, outdoor patio and barbecue grill. Great for evening get togethers and celebrations.

Oasis privado con piscina en residencial tranquilo
Private pool just for you. Independent attached house with large garden and terrace ideal to enjoy as a family. Located in a quiet and safe residential area, close to everything. Air-conditioned and comfortable spaces. Perfect for getaways, weekends and a break in the city.

Mamuchi House, Zona Franca San Isidro, base aérea
2 bedroom apartment with A/C, private bathroom, 3rd floor. Ideal for you if you are looking for a comfortable space near the Free Trade Zone of San Isidro and Air Base, rest in a family atmosphere. Base rate valid for 2 people, one room.

Your cozy little guest house
Enjoy your stay! Comfortable and pleasant guest house on the ground floor (no stairs, no elevators) cool patio, in the city center, near the Quisquella Stadium, Plaza de la Salud, shopping malls, etc.
Popular amenities for Santo Domingo guesthouse rentals
Family-friendly guest house rentals

Room near the neighborhood and bus stations

Cozy room near Chinatown

affordable inn

save your pocket

Luxury house aut Americas 2 minutes Garrido

twin bed room

Our Home Zudelyn H8

Spacious room on a budget
Guest house rentals with a patio

Nochebuena Room at Akaiah Guest House.

Giuliela Boutique Stay – Entire Residence

Villas Na’ Keys

The best option

Beautiful room in the Colonial area

Relax in this cozy villa

Double suite room in Aut Las Américas

Charming Shelter - Suite #5
Guest house rentals with a washer and dryer

INVERTERS

Brisa Oriental

Bedroom inside apartment

Family-friendly and comfortable

Villa el paraíso, Guerra

Luxury apartment in Santuario

Casa en Villa Marina, Los Ríos de Santo Domingo

Secure★DCGen★Full Kitchen★100+Mbs★Comfy Bed★W/D
When is the best time to visit Santo Domingo?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $36 | $35 | $35 | $29 | $28 | $27 | $26 | $29 | $35 | $29 | $28 | $27 |
| Avg. temp | 78°F | 78°F | 79°F | 80°F | 81°F | 82°F | 83°F | 83°F | 83°F | 82°F | 81°F | 79°F |
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- Zona Colonial
- Playa Nueva Romana
- Ciudad Juan Bosch
- Playa Hemingway
- Malecón
- Metro Country Club
- Playa Guayacanes
- Santo Domingo Country Club
- Teatro Nacional Eduardo Brito
- Blue Mall
- Megacentro
- Centro Olímpico Juan Pablo Duarte
- Downtown Center
- Félix Sánchez Olympic Stadium
- Parque Iberoamerica
- Cotubanamá National Park
- Bella Vista Mall
- Cathedral of Santa María la Menor
- Enriquillo Park
- Dr. Rafael Ma. Moscoso National Botanical Garden
- Galería 360
- Agora Mall
- Malecón de San Pedro de Macorís
- Plaza De La Cultura
- Things to do Santo Domingo
- Things to do Distrito Nacional
- Nature and outdoors Distrito Nacional
- Things to do Dominican Republic
- Tours Dominican Republic
- Art and culture Dominican Republic
- Sightseeing Dominican Republic
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- Entertainment Dominican Republic
- Sports activities Dominican Republic
- Food and drink Dominican Republic
- Family travel hub Tips and inspiration
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- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes




