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Hotels in Panama

Find and book unique hotels on Airbnb

Top-rated hotels in Panama

Guests agree: these hotels are highly rated for location, cleanliness, and more.

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Superhost
A vibrant terrace features colorful umbrellas shading lounge chairs around a refreshing plunge pool. Lush greenery surrounds the area, complementing the bright yellow walls of the two-story building in the background, which overlooks the scenic landscape.
Hotel room in Taboga

Eco Lodge Mango Room Plus New

You’ll be charmed by this special room for two. This ground floor room with two ocean and garden view windows offers a pillow top double Bed/Full (137cm x 190cm), 2 bedside lights, free WiFi, a flat-screen smart TV, and a private ensuite bathroom with a shower. Enjoy the shared balcony with ocean, tropical garden or forest view and to a shared hammock area. Additionally enjoy: Plunge Pool -Sun Terrace - Gardens - Nearby ancient forest. Pets in suites only, not this room. Room is air conditioned.

LocationFamilyHospitality

4.91 out of 5 average rating, 23 reviews
Superhost
Hotel room in Isla Contadora

Avani Eco Hotel~ DualBed Suite ~ Kitchenette & TV!

Step into the comfort of this beautiful queen suite in the high-end, eco-friendly Avani Boutique Hotel, offering easy access to sandy beaches and the many stunning amenities and activities of Contadora Island. Spend the day exploring this breathtaking island and then retreat to the attractive suite whose stylish design and scenic surroundings will mesmerize you. ✔ Comfy King Bed and Full Futon Bed ✔ Spa-Like Bathroom ✔ Private Patio ✔ Wi-Fi ✔ Hotel Amenities (Breakfast, Transport, Activities)

FamilyGetting aroundComfort

5.0 out of 5 average rating, 4 reviews
Guest favorite
Hotel room in Rio Hato

Ibiza Village Pool, Villa Rental with Pool

What you need is not just a break, it's freedom. In Ibiza Pool, 24/7 pool, Bijao beach 5 min away, independent rooms. Cook, drink, laugh, live without schedules — safe, private space designed for your disconnection. Book today and experience what you deserve What you need isn't just a break - it's freedom. At Ibiza Pool, 24/7 pool, nearby beach, and private rooms. Cook, drink, laugh, and relax, in a safe, private space designed for real disconnection. Book now. Live the moment you deserve.

FamilyLocationBathroom

5.0 out of 5 average rating, 13 reviews
Guest favorite
Hotel room in Boquete

Couples Garden Retreat in Boquete

Located on the sought after Avenida Buenos Aires in Palo Alto, Boquete, we are a nature lovers paradise. Nestled in a beautiful property with many trees and the sound of the creek located right behind the room. Enjoy your complimentary breakfast at the gazebo over the creek for a relaxing morning. Surrounded by mountains and fresh air, this is the perfect place to unwind and enjoy the beauty of Boquete. Restaurant on site for breakfast, lunch and dinner open every day.

LocationWalkabilityKitchen

4.75 out of 5 average rating, 8 reviews
Guest favorite
Hotel room in Colon

Triple Room near Colón Free Zone & Cruise Port

Your strategic connection in the heart of Colón. At Hotel Internacional, we offer the perfect balance between comfort and location. Just steps from the Colón Free Zone and the main cruise terminals (Colón 2000), we are the ideal choice for both business travelers and tourists. Enjoy rooms with air conditioning, high-speed Wi-Fi, and personalized service that will make you feel at home. Security, cleanliness, and efficiency ensure a seamless and comfortable stay.

LocationHospitalityView

5.0 out of 5 average rating, 5 reviews
Guest favorite
A covered terrace with wooden beams provides shade over a seating area featuring a wooden table and chairs. A hammock is suspended nearby, while tropical plants add greenery to the inviting outdoor space. The building's arched windows reflect the bright sky and surrounding palm trees.
Hotel room in Las Lajas

Beach Apartament Villa Deluxe

Disfruta de una estancia inolvidable en los apartamentos Villa Deluxe de playa Las Lajas. Estos acogedores apartamentos te brindan comodidad y estilo, con vistas espectaculares y un acceso directo a la playa. Relájate en su balcón privado o sumérgete en la piscina tropical para refrescarte. Con una ubicación privilegiada y servicios de primera clase, los apartamentos Villa Deluxe son el lugar perfecto para disfrutar de unas vacaciones de ensueño.

LocationValueKitchen

4.86 out of 5 average rating, 86 reviews
Top guest favorite
Hotel room in Chame

P/Caracol Ocean Haven View (C5-PBB) 2 bed, 2 bath

This unique place has a style all its own, steps away from the ocean and fully furnished ground floor unit 2 bed/2 bath apt has an open concept living, dining & kitchen space and an outside pergola area. (4 guests). This is a unique villa apartment over looking the picturesque Playa Caracol coast with ocean front and majestic mountain views and great on-site amenities. 1km of beach to offer you the best beach and surfing experience around.

FamilyValueCheckout

4.86 out of 5 average rating, 120 reviews
Guest favorite
A cozy hotel room is showcased with a spacious bed dressed in white linens and a red throw blanket. A wooden desk with two cups and a remote is positioned beside the bed. A soft lamp and a wall-mounted TV complete the inviting atmosphere.
Hotel room in El Cangrejo

Cuarto de hotel #3 a una cuadra del Metro.

Disfruta de acceso ràpido a los destinos más populares de Ciudad de Panamà, centros comerciales, restaurantes, y áreas turísticas. Cuarto de hotel con baño privado, aire acondicionado, cable TV, recepciòn con 24 horas de servicio y estacionamientos sujetos a disponibilidad. Cerca de restaurantes y casinos. A una cuadra de la estaciòn del Metro que lo lleva en 10 minutos a Albrook Mall, el Centro Comercial más grande de Panamà.

ValueLocationWifi

4.78 out of 5 average rating, 50 reviews
Guest favorite
Hotel room in San Carlos

The Pearl – Romantic Oceanfront Hideaway – Panama

Charming and intimate, The Pearl is perfect for couples looking to unwind by the Pacific Ocean. Situated between Playa Coronado and Playa Blanca and close to the lush landscapes of El Valle de Antón, the suite includes a queen-size bed, a private open-air shower, and an oceanfront balcony. Though it does not include a kitchen, guests enjoy private beach access and personalized concierge offerings to make every stay effortless.

ValueLocationComfort

4.97 out of 5 average rating, 90 reviews
Guest favorite
Hotel room in Panama City

Executive Suite Financial District/Pool·Gym

Elegant suite located in the Megapolis Hotel, in the heart of Panama City. Modern and comfortable space, ideal for business trips or tourism. Strategic location near the Financial District, restaurants, shopping malls, nightlife and tourist attractions of the city. Enjoy access to high-level common areas, pool, gym and amenities that combine meals, rest and entertainment in one place.

ValueLocationPool

4.79 out of 5 average rating, 14 reviews
Superhost
Hotel room in Bocas del Toro Province

Cozy & Bright - Private Double Room

This small and bright double room is ideal for a couple or solo traveler. You can enjoy a nice jungle view all around from the bed as well as from your shower. You can use a shared kitchen and all of our public terraces. The perfect place to travel if you like to sleep in real nature with an ocean steps away, and with animals around you.

LocationHospitalityShared spaces

4.89 out of 5 average rating, 9 reviews
Guest favorite
A cozy room features a double size bed with striped bedding and a piece of artwork above. A glass-enclosed shower is visible to the right, with a small stool nearby. Soft natural light filters through a sheer curtain, illuminating the space.
Hotel room in San Felipe

Beautiful small loft #3 - double size bed

Enjoy charming "Corcho rooms" in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant and apartments upstairs. "Corcho" is luckily situated in the central, restored part of Casco. Most of the buildings around are restored and the neighborhood is safe.

ValueLocationHospitality

4.79 out of 5 average rating, 84 reviews

Destinations to explore