Vacation rentals in Panama
Book unique homes, vacation rentals, and more on Airbnb
Top-rated vacation rentals in Panama
Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama vacation rentals
House rentals in Panama
Condominium rentals in Panama
Beach house rentals in Panama
Your guide to Panama
All About Panama
A narrow isthmus on the southern tip of Central America, Panama is the cultural gateway to South America and the geographical gateway between the Caribbean Sea and the Pacific Ocean. Panama City, its stunning capital city, juxtaposes old-quarter Casco Viejo against the shiny, soaring skyscrapers of the modern district — all surrounded by rolling green hills and vast blue ocean studded with tiny islands. The Metropolitan Natural Park, a wildlife refuge threaded through with hiking trails, is just 10 minutes away from downtown. And Taboga Island, a volcanic enclave featuring a rich array of plants as well as white-sand beaches, is easily reachable via a 30-minute ferry ride.
The terrain rises dramatically from white-sand Caribbean beaches to lush mountain jungles. Near the top of the country, altitude-wise, you’ll find Boquete, home to world-renowned coffee plantations, and the Quetzal Trail, one of Panama’s most scenic hiking trails. Leaving from Volcan Baru National Park, it passes through the Talamanca Mountain Range, where you’ll discover rare tropical wildlife including spider monkeys, tapir, and brightly colored frogs.
The best time to stay in a vacation rental in Panama
The lovely tropical climate makes the prospect of securing a vacation rental in Panama appealing all year long. The drier winter months are ideal for hitting the country’s hiking trails or visiting the beaches. Many of the country’s most significant religious festivals, including Carnaval and Semana Santa (Holy Week), occur in March and April. You’ll want to keep this in mind when booking your Panama house rental if you are headed to a city that hosts a big celebration.
Once Panama’s rainy season starts in May, the sunshine is interrupted with short bursts of heavy rain. It is also usually the quietest time of year for tourism, and you may find yourself alone in the country’s national parks or beaches. That all changes, of course, after the rainy season finishes in November and gorgeous, sunny weather returns.
Top things to do in Panama
Casco Viejo
As the oldest part of Panama City, settled in 1673, Casco Viejo is filled with beautifully restored French and Spanish-style buildings, with a touch of art deco flair. As you stroll down the cobblestone streets, past pastel-colored buildings housing trendy restaurants, upscale bars, and inviting coffee shops, time seems to shimmer between the 19th and 21st centuries. Explore the neighborhood during the day; return after dark for its lively nightlife.
Panama Canal
When the 51-mile Panama Canal opened in 1914, it provided a waterway through Central America and reduced the traveling distance between the Pacific and Atlantic Ocean by 8,000 miles. The impact that this had on global commerce is hard to underestimate. The Pacific mouth of the canal is 26 miles outside Panama City, making it easy to visit this engineering marvel and watch as enormous ships rise and descend through a series of locks.
Bocas Del Toro
Lying close to the border of Costa Rica, this collection of islands is Panama's most popular beach destination. Largely undeveloped, the islands are home to lush tropical rainforest. Great snorkeling and diving opportunities abound in the Isla Bastimentos National Park, which is home to a wide variety of Caribbean coral species as well as (gentle) nurse sharks, crab, and stingrays.
Destinations to explore
- Chalet rentalsPanama
- Mansion rentalsPanama
- Island rentalsPanama
- Kid-friendly rentalsPanama
- Rentals with a fireplacePanama
- Rentals with breakfastPanama
- Rentals with a kayakPanama
- Rentals with outdoor seatingPanama
- Rentals with a hot tubPanama
- Villa rentalsPanama
- Farmstay rentalsPanama
- Tiny house rentalsPanama
- Family-friendly rentalsPanama
- Guesthouse rentalsPanama
- Monthly RentalsPanama
- Boat rentalsPanama
- Beach condo rentalsPanama
- Beach house rentalsPanama
- Events allowed rentalsPanama
- Rentals with a patioPanama
- House rentalsPanama
- Cabin rentalsPanama
- Loft rentalsPanama
- Nature eco lodge rentalsPanama
- Apartment rentalsPanama
- Pet-friendly rentalsPanama
- Hostel rentalsPanama
- Bungalow rentalsPanama
- Rentals with lake accessPanama
- Rentals with an accessible height bedPanama
- Waterfront rentalsPanama
- Wheelchair accessible rentalsPanama
- Fitness-friendly rentalsPanama
- Hotel rentalsPanama
- Rentals with a saunaPanama
- Rentals with a home theaterPanama
- Serviced apartment rentalsPanama
- Vacation home rentalsPanama
- Rentals with a fire pitPanama
- Treehouse rentalsPanama
- Smoking-friendly rentalsPanama
- Rentals with an EV chargerPanama
- Rentals with a washer and dryerPanama
- Beachfront rentalsPanama
- Bed and breakfastsPanama
- Rentals with beach accessPanama
- Rentals with poolsPanama
- Townhouse rentalsPanama
- Condo rentalsPanama
- Boutique hotel rentalsPanama
- Cottage rentalsPanama
- Yurt RentalsUnited States
- Yurt RentalsUnited Kingdom
- Castle RentalsUnited States
- HouseboatsUnited States
- Holiday CaravansUnited Kingdom
- Private Island RentalsUnited States
- Farm HousesUnited States
- Farm CottagesUnited Kingdom
- Cabin RentalsAustralia
- Luxury CabinsUnited Kingdom
- Luxury CabinsUnited States
- Holiday ChaletsUnited Kingdom
- Cottage RentalsUnited States
- Holiday CottagesUnited Kingdom
- Mansion RentalsUnited States
- Villa RentalsUnited Kingdom
- Holiday BungalowsUnited Kingdom
- Bungalow RentalsUnited States
- Condo RentalsUnited States
- Holiday ApartmentsAustralia
- Holiday HousesUnited States
- Holiday HousesUnited Kingdom
- Private Holiday RentalsUnited Kingdom
- Big House RentalsUnited States
- Big CottagesAustralia
- Large VillasUnited Kingdom
- House Rentals with a PoolUnited States
- Cabin Rentals with a PoolUnited States
- Villas with a PoolUnited Kingdom
- Apartments with a Hot TubUnited States
- Holiday Cottages with a Hot TubUnited Kingdom
- Beach CabinsUnited States
- Beach CondosUnited States
- Beachfront RentalsUnited States
- Beach HousesUnited Kingdom
- Beach VillasUnited Kingdom
- Coastal CottagesUnited Kingdom
- Pet-Friendly Vacation RentalsUnited States
- Pet-Friendly Beach RentalsUnited States
- Pet-Friendly Cabin RentalsUnited States
- Dog-Friendly CottagesUnited Kingdom
- Luxury Dog-Friendly CottagesUnited Kingdom