Guesthouse vacation rentals in Panama

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Panama

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Guesthouse in Anton Valley

4.88 out of 5 average rating, 60 reviews

Private 1 BR cottage near India Dormida hiking

This fully equipped 1 bedroom cottage has been a high rated Super Host Airbnb favorite for 5 years. It now has an equally fabulous new owner and Airbnb requires a fresh start. Relax into the hammocks in this peaceful residential setting where birds and butterflies abound. The cottage opens to a wonderful private garden sitting area and gives you a fantastic view of India Dormida mountain and nearby hiking trail. A short (~1 mile) walk to the town with shops, restaurants and daily Farmers Market.

Guest favorite

Guesthouse in Los Naranjos

4.93 out of 5 average rating, 212 reviews

Sunshine Cottage at Finca Katrina

Sunshine Cottage is a little cottage in the back garden of Finca Katrina. It is set on a hill with views of Palo Alto and Jaramillo with a coffee plantation in the foreground. There is a full (double) bed, room to hang your clothes and to store your belongings. You have a small fridge, toaster oven, sink, coffee maker, and cupboard space for food, but no stove top. If you are looking for more bedrooms, there are additional units on Finca Katrina that compliment Sunshine Cottage. Send us a note!

Guest favorite

Guesthouse in Bajo Boquete

4.84 out of 5 average rating, 62 reviews

Rustic Private Studio Near Downtown

Please note that the cabin is conveniently located near the main street, which can occasionally result in some street noise. Rustic Cabin Small rustic cabin, ideal for individuals or groups of two seeking a place to stay while exploring Boquete. The property features on-site parking and easy access to the town center, whether by walking or by car. It is conveniently located near a large supermarket and easily accessible by bus. Situated on the second story, it has a completely private entrance.

Top guest favorite

Guesthouse in San José

4.96 out of 5 average rating, 25 reviews

Guesthouse in Punta Barco Resort

Guest house in Punta Barco Resort with access to 2 pools and private beach (nearby Coronado). The separate entrance accessible two-story guest house has both a sleeping area (downstairs) and a living area (upstairs). The 1st pool is right in front of your guest house. The 2nd communal resort pool with stunning sea views is located next to the resort's private beach within the resort complex and can be reached in a short drive by car. The use of the beach depends on the weather and the tides.

Top guest favorite

Guesthouse in Torio

4.91 out of 5 average rating, 129 reviews

Torio guesthouse with panoramic view

Our private guesthouse is suspended over the Torio River, on the west coast of the Azuero Peninsula. It is a paradise for hikers, bird watchers, surfers and beach goers. Marked trails with posted maps begin at our place. Hike to a beautiful waterfall, mountain or beach. Photograph birds from the porch. Surf, body board and swim safely (no strong currents). Walk to good restaurants, and a small grocery. Experienced Surfers have Morrillo Beach and Playa Reina. Watch sun and moon rise.

Guest favorite

Guesthouse in Río Hato

4.88 out of 5 average rating, 90 reviews

Sustainable Guest house with Pool in Rio Hato

Discover Rancho Ahome, a serene 2BR 1Bath guesthouse in Rio Hato. Escape to tranquility, 5 mins from stunning beaches, and enjoy our private pool with a waterfall. Immerse in nature on our sustainable farm, home to fruits, rabbits and chickens. Perfect for those seeking peace and an eco-friendly retreat, Rancho Ahome offers a blend of comfort and adventure amidst breathtaking landscapes. Experience a peaceful sanctuary that’s close to nature yet filled with comfort. We are pet friendly.

Top guest favorite

Guesthouse in La Enea

4.96 out of 5 average rating, 47 reviews

Country House with Pool in La Enea de Guararé

Get out of the capital city and come and enjoy Panamanian folklore in a rustic yet cozy space with an autochthonous experience. Lounge in the pool or lounge in a hammock, breathe fresh air, close to the ocean, surrounded by wide, natural gardens for a good walk. Close to the Port of Guararé where you will enjoy the best seafood and drinks or enjoy the heart of the best folklore event highlighting the traditions and the best Panamanian polleras.

Top guest favorite

Guesthouse in La Ermita de San Carlos

4.96 out of 5 average rating, 126 reviews

Rural w/ comfort: AC, WiFi, pool, hot water.

The Small House is part of 5 cabins called “A Piece of Paradise” plus the House where the hosts live; Registered in the Panamanian Tourism Authority Bureau. ✸ Ideal for a couple or a single person ✸ Outdoor dining area and hammock ✸ Very quiet neighborhood ✸ Private and public transportation available, just ask and we will help you ✸ 7-10 minutes, by car, from Playa La Ermita and 10 minutes from Playa El Palmar (great spot for surfing)

Top guest favorite

Guesthouse in Bocas del Toro

4.94 out of 5 average rating, 50 reviews

The Boat House in Big Bight

Come relax in this peaceful over the water bungalow on Isla Colon, on a coral reef 15 minutes away from town BY BOAT ONLY.. See lots of stars in the sky, tons of sea life & stunning sunsets from your balcony! Enjoy Starfish Beach, just a 5 minute boat ride away. Red Frog Beach, Playa Bluff, Zapatillas, & much more while you're here in Bocas Del Toro! (Kitchen is provided with basic cooking essentials & bathroom with basic personal items).

Superhost

Guesthouse in La Loma

5 out of 5 average rating, 3 reviews

Beachfront Private Studio, Ground Level in Jungle

Private Studio Suite on the ground level of our guesthouse with STARLINK WIFI. A backup internet provider if required. Backup power generator. Top quality queen size bed. It's perfect for relaxing, enjoying the sounds of the jungle and ocean without neighbours, roosters, barking dogs or traffic. Only a few steps away from our 1 Km sandy beach. Next to Surfing Beach. Pool access all day long.

Superhost

Guesthouse in San Carlos

4.71 out of 5 average rating, 7 reviews

(5) The Beach House Inn - The Santa Cruz Room

The Santa Cruz Room offers a clean, safe and serene rest just a short walk from the beach. This room offers your own private entrance, a double bed, coffee maker and sink and full private bathroom. Walking time in minutes... The Beach: 3 San Carlos village: 7 Vista Mar Marina: 15 El Palmar (surfing): 15

Superhost

Guesthouse in Rio Sereno

5 out of 5 average rating, 3 reviews

The Farmer’s Shack - Pure Nature

Relax and catch your breath with the whole family at this peaceful place. Do you like camping? Plenty of space to set up a fire and enjoy a glass of wine! This is the perfect spot to get disconnected and enjoy the quietness without noise or distractions! No internet or Cable TV on premises.