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Mansion vacation rentals in Panama

Find and book unique mansions on Airbnb

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Popular amenities for Panama mansion rentals

Luxury mansion rentals

Top guest favorite
Apartment in Maria Chiquita
5 out of 5 average rating, 23 reviews

Playa Escondida ocean and lagoon view #familyvacation

AlbertoRating, 5 stars2 weeks ago
Mrs. Carolina was extremely attentive, we had a wonderful time.
Guest favorite
Villa in Las Lajas
4.81 out of 5 average rating, 32 reviews

Beach House Where Emy

TylerRating, 5 stars1 month ago
Great place we want to go back already.
Superhost
Villa in Playa Venao
4.8 out of 5 average rating, 51 reviews

Villa Nomada -Barefoot Luxury Beach Front Villa

FranciscoRating, 5 stars1 month ago
Great place to stay at Venao. Clean and comfortable. Would stay again
Top guest favorite
Condo in Maria Chiquita
5 out of 5 average rating, 49 reviews

Playa Escondida Lux Beachfront Haven:Oceanview Apt

LorenRating, 5 stars1 week ago
First Playa Escondida is a very beautiful place, white sand beaches, shallow seas beach for kids. The sand is much whiter then most of Panama. Has many activities and nice beach rentals. The condo of Sammy is one of the most complete Airbnb’s we have stayed. His space has the best amenities inside. Samy is very responsive and helpful. Playa Escondida is our favorite long weekend escape from the city.
Guest favorite
Cottage in Panama City
5 out of 5 average rating, 17 reviews

Hacienda La Perezosa in Cerro Azul

KarinaRating, 5 stars2 weeks ago
We had very high expectations of the place and we were not disappointed. We felt welcome from the moment we arrived. The place offers you the service of a housekeeper who helps you during your stay, she welcomed us as if we were arriving at a relative's house, she assisted us in the kitchen. He prepared breakfast and provided any other support we needed in the kitchen at other times. The place is comfortable for 10 people, spacious, it has a beautiful lake that is worth it just to be there, you can ride in kayaks that are included, walk around the property, play board games or do outdoor activities like playing ball. We were able to take the dogs, who were happy. We really want to go back. It's important to bring your meals because there are no restaurants nearby. You won't regret going to Hacienda la Perezosa, and you'll want to come back. Congratulations on this beautiful place just 1 hour from the city.
Superhost
Apartment in Panama City
4.85 out of 5 average rating, 48 reviews

Penthouse deluxe, 360Âş views and glass pool

HaroldRating, 5 stars2 days ago
This is the 2nd time staying at this facility and it was again top notch, high quality and upscale. We will come back for the 3rd time in the near future.
Superhost
Boat in RĂ­o AzĂşcar
5 out of 5 average rating, 4 reviews

Private Luxury Catamaran

ChrisRating, 5 stars1 month ago
Our catamaran stay in San Blas was incredible! The islands were pristine and beautiful, far from the tourist crowds. The captain was super responsive and knew all the hidden gems, taking us to the best spots. The service and food on board were excellent—fresh, local, and delicious. It was the perfect way to explore the islands in comfort and style. Highly recommend for anyone seeking a unique and unforgettable experience!
Superhost
Home in Coronado
4.74 out of 5 average rating, 23 reviews

CHARMING HOUSE IN FRONT OF THE SEA WITH POOL-CROWNED

Pierre-PaulRating, 5 stars3 months ago
Classic Playa Coronado Beach House. Older open air home on the beach with pool, and playground for the kids. The house was as described, reviewed and as expected. Each bedroom had comfortable beds, A/C, and bathroom. It was perfect for our 5 day stay with family and kids. Marcela was a responsive host for any questions/problems. Daniel the grounds keeper was very nice and helpful as well if you needed anything. My kids loved the beach, pool and especially the playground. Great location and many restaurants and groceries stores within 10 mins or less. I would stay here again.

Pet-friendly mansion rentals

Superhost
Cottage in Panamá Oeste
4.83 out of 5 average rating, 12 reviews

Iwanna Green, Country House with Pool

MonicaRating, 5 stars4 months ago
A totally ecological house with activities for the whole family, a pool surrounded by nature and a theme that makes you want to take out your inner child and have a good time with friends and family while you are surrounded by a cool climate in the bell mountain. Easy access, diversity and neon art in each area of the house, multiple cooking utensils and appliances. .
Guest favorite
Villa in San José
4.83 out of 5 average rating, 58 reviews

The Big Family Mini Resort House @Punta Barco

DanielRating, 5 stars2 weeks ago
What we loved: The overall experience was great, we liked the place a lot, the place is exactly as described. Everything was super clean.
Superhost
Cabin in Calobre
4.83 out of 5 average rating, 18 reviews

La Yeguada - Forest Point Cabin

StefanieRating, 5 stars1 week ago
Flexible check-in, a variety of kitchen utensils and others that made the stay very pleasant, everything was clean and organized.
Guest favorite
Villa in El ChirĂş
4.87 out of 5 average rating, 38 reviews

Beach house for families with a pool.

Judy AnnRating, 5 stars1 week ago
The house was very nice, we stayed for 2 days, and it was very comfortable and we had a great time, there were many things to do such as a pool, concierge, football and more, and the rooms were comfortable and each one with its bathroom, it was very close to the beach that was private and very nice and everything was tidy and it was pet friendly, I recommend it to all of us charm
Top guest favorite
Villa in Punta Chame
4.98 out of 5 average rating, 118 reviews

Beach House with Pool/Gazebo in Punta Chame!

KarimaRating, 5 stars1 month ago
A great option to spend family time, relax and above all, feel at home, just what I was looking for and needed. I would go back many more times It's a home that has everything you could need and more, with lots of amenities, and the pool is the center of total enjoyment. Polina was very nice and thoughtful with her attention. Lots of privacy to enjoy free time. The nearby beach is very quiet almost at the exit of Chame Bay. Great stay.
Superhost
Home in La Guaira
4.68 out of 5 average rating, 73 reviews

Villa Mar y Luna

Holdemar JaelRating, 5 stars1 month ago
Second time in this place and I still think it is a small piece of heaven on the middle of the beach
Guest favorite
Home in FarallĂłn
4.91 out of 5 average rating, 56 reviews

Beach & Golf VILLA HOUSE on the Beach

JoeRating, 5 stars2 months ago
Had an awesome stay with the family at this villa on the golf course. I intended to get in a round of golf, but weather and other commitments didn't allow it. The villa is huge and had plenty of space for all 11 people in our group. The kids loved the pool, and even some of the adults got in a quick dip as well. We had access to the beach club which was a nice benefit we really didn't expect. There are several restaurants nearby that are not attached to the resort, so don't feel like you have to eat at the resort restaurants. We paid extra to have the golf cart which we were able to enjoy during the day, but the headlights didn't work so we couldn't use it at night. While you're in the area, recommend a day trip to El Valle. Unfortunatley, for us, it rained heavily for like an hour straight, but after that we were able to walk up and down Central Ave. Overall, it was a great trip and Eva's villa made it so easy for us to relax and enjoy each other's company. Highly recommend!
Guest favorite
Cottage in Anton Valley
4.86 out of 5 average rating, 109 reviews

Gaital/Gaital View View

MitkoRating, 5 stars2 months ago
Visited this villa for two nights with a group of 10 persons. We slept on open windows with all the sounds of the nature around the house. It is located outside the towns centre but all of us were ok with the 15min walk, also available public minibuses. The house is beautifully designed and decorated and this makes big and lasting impression. Also excellent equipment in the kitchen! Hot water and several and functional bathrooms. Nice and responsive host. This place is amazing, I highly recommend it.

Mansion rentals with a pool

Top guest favorite
Villa in RĂ­o Hato
5 out of 5 average rating, 28 reviews

Villa Agueda Decameron, golf club and swimming pool

JeremyRating, 5 stars2 months ago
What a place, one of the better Air B &B’s in Panama, have everything you require, nice pool, cold jacuzzi that works, very amazing stay Annelise, thanks for everything.
Home in Playa Venao
4.89 out of 5 average rating, 126 reviews

Beautiful Home Directly on Playa Venao Sleeps 8-10

DanRating, 5 stars1 month ago
This house feels like something out of a dream. Watching sunsets on the beach, right in the backyard, was an absolute highlight. The location is incredibly convenient, offering direct access to the peaceful, nature-filled side of Playa Venao. You can even check the surf break from the master bedroom and decide if it’s worth getting up for an early surf session. The house itself is spacious, comfortable, and genuinely cozy, without the overly staged feel some rentals have. It truly felt like a home, and I hope to return again. The hosts were exceptional—unbelievably responsive and attentive. Anytime we needed something, they were there within minutes. Thank you for an amazing stay!
Guest favorite
Home in Panama City
4.94 out of 5 average rating, 34 reviews

Nice duplex house with a swimming pool.

SeanRating, 5 stars1 month ago
Panama is a beautiful country with many beautiful people, Gerardo is definitely one those people. He was fun, polite, helpful and understanding. He was a wealth of knowledge with good intentions, we found some great locations because of him. The house was perfect for us, spacious rooms, beautiful decor, relaxing balcony and a wonderful backyard pool. The location was Uber friendly and safe to walk and relax. When we return to Panama, Gerardo and his place will be on top of the list. ❤️
Top guest favorite
Villa in Boca Chica
5 out of 5 average rating, 12 reviews

On the Beach Villa in Boca Chica!

MartinRating, 5 stars2 months ago
We spent a month in this beautiful house, and it’s probably as close to paradise on earth you can find. The house is spectacular. The view is breathtaking. The beach is perfect sand and so calm that it feels like a private beach. Lance and Monty are incredible hosts and Carol and Jennie locally made us feel like family and were already responsive right away. The kitchen is perfect to prepare anything. It is very secluded, and it’s exactly what we looked for. But expect to drive 20+ minutes to get anywhere. But … it’s worth it for the calm and rest you will enjoy in the house. Perfect on all level !
Guest favorite
Cottage in Panama City
5 out of 5 average rating, 12 reviews

In a magical forest there is a cabin.

IvanRating, 5 stars1 month ago
The place is the place for those looking for solitude. You neither see nor hear everyone; the closest house is about half a mile away. Yet, the internet is fast and reliable there, and all concerns, if any would arise, are addressed promptly and proactively. The drive down the river valley is steep but doable in almost any high-clearance vehicle, even without 4WD, although a good SUV or pickup is preferable. The house sits on a flat valley along the creek, and the grounds are easy to walk around. Two pools, one air temperature, one slightly warmer, are in good order. The beds are comfy, each with its bathroom. The kitchen is well-equipped. We were not lucky enough to spot wildlife, yet we glimpsed a few toucans, oropendolas and a couple of capuchin monkeys. It's a great place to relax and unwind.
Guest favorite
Cottage in Chame
4.93 out of 5 average rating, 27 reviews

Beautiful Country House with Pool 5 Bedrooms

Benjamin FranklinRating, 5 stars1 week ago
Thank you very much Janeth for your excellent attention at all times. We congratulate you on your beautiful beach house. I assure you that on other holidays we will be back. God bless you. Thanks again for everything.
Guest favorite
Townhouse in Nueva Gorgona
4.88 out of 5 average rating, 16 reviews

Lux Beachfront Oasis in Gorgona

AngelRating, 5 stars1 week ago
Great stay with beautiful beach access and views! The space was adequate and comfortable. Despite minor inconveniences, the host's excellent customer care made all the difference. We'd like to come back in our next family retreat. Highly recommended!
Guest favorite
Home in Playa Coronado
4.84 out of 5 average rating, 19 reviews

Spacious home in Coronado Golf

KeysiRating, 5 stars2 weeks ago
Beautiful accommodation, the house was super spacious, quiet, the rooms were beautiful each room had its own bathroom. The clean, beautiful garden overlooking the golf course, the terrace in front of the pool was ideal for breakfast and dinner together! I definitely look forward to coming back and recommend it 100%. The host Alexandra was always attentive, responsive and very friendly. Thank you for everything

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