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Mansion vacation rentals in Panama

Find and book unique mansions on Airbnb

Top-rated mansion rentals in Panama

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An outdoor area features a private plunge pool surrounded by wooden decking and sun loungers. A blue shade sail offers protection from the sun. Lush greenery and a vibrant blue fence enhance the tropical ambiance, with glimpses of the water visible in the background.

Home in Bastimentos Island

4.82 out of 5 average rating, 127 reviews

Spacious, Over the Water Home with Plunge Pool

Perched over the water in Bastimentos Bay, this well-appointed four bedroom and three bath single family home combines classic Caribbean architecture with modern sensabilities. With over 2,000 sq ft of comfortably furnished spaces, there’s room enough for eight adults to spend time together - or apart - in any weather. BBQ poolside, stargaze from the hammocks, fish off the dock, walk to restaurants, or flag down a water taxi from your private boat dock for the ten minute trip to Bocastown.

Villa in Farallon

4.9 out of 5 average rating, 230 reviews

Costa Blanca Beach & Golf Villa by Decameron

Spacious Villa with Pool, Golf Views & Beach Access Relax in this stylish 4-bedroom villa overlooking the 7th putting green of Mantarraya Golf Course. All on one level, it offers 250 sq m of comfort, with en-suite bathrooms and space for up to 12 guests. Wow ! - Private 15 m pool with shallow area - 15-minute walk to Pacific beach - Access to Owners Beach Club (restaurant + parking) - Peaceful golf course setting Perfect for families, groups, or golf lovers seeking sun and serenity.

The exterior of the three-story beach house is showcased, featuring terracotta roofs and lush landscaping. Palm trees and colorful flowers enhance the vibrant surroundings, while the ocean is visible in the background, complementing the peaceful neighborhood setting.

Home in San Carlos

4.95 out of 5 average rating, 126 reviews

OceanView-Rooftop Jacuzzi&Pool | Concierge Service

Unique 3-story beach house – one of a kind. 7 bedrooms, 13 beds, 8.5 baths. hot water. Every room with full bath -AC’s and ceiling fans in all rooms, separate laundry -Rooftop area pool, Jacuzzi, bar, BBQ(charcoal & gas) with amazing ocean view -High ceilings, large open kitchen and living area. -Spacious balcony for dining or relaxing. - 5 min. walk to the beach. -Parking for up to 7 cars - Base rate covers up to 4 guests, with a $40 charge per additional person, per night.

A spacious living area features a large green sectional sofa, a glass coffee table, and modern pendant lighting. The dining space, visible in the background, includes a round table and white chairs. Natural light floods the room through expansive windows, creating an inviting atmosphere.

Apartment in Panama

4.95 out of 5 average rating, 104 reviews

5A - Boutique Apartment ! High end furnished! 4BR

This stylish place to stay is perfect for group trips, breathtaking furniture, the green and natural lighting will definitely make this stay a great one! We have many apartments in the same building, in case the entire date you would like to stay is not available, contact us and we will gladly organize your stay! Sorry for the inconvenience if you write us on Friday’s past 5pm our time and on Saturday’s we will reply on Saturday night around 8pm our time best regards!.!

Top guest favorite

The image shows a bright outdoor area featuring a clear blue swimming pool bordered by light stone paths and lush green grass. A tall palm tree provides shade in the foreground, while the backyard includes a single-story house and an open patio area under a roof.

Villa in Punta Chame

4.97 out of 5 average rating, 129 reviews

Beach House with Pool/Gazebo in Punta Chame!

"Disconnect from the routine and enjoy a sunny environment. Just breathe fresh air in a different surroundings. Enjoy a few days in the pool, relaxed in a hammock and of course steps from a spectacular beach with views of the city and islands. The house has 4 bedrooms, 3.5 bathrooms, electric plant and all the facilities to enjoy and rest. Close to restaurants and the best beach to do and see kitesurfing adventures, fish, SUP, etc. Only 90 minutes from the city"

A spacious outdoor deck features modern furniture arranged for relaxation, overlooking a lush mountainous landscape. Verdant hills and a colorful sky at dawn create a tranquil environment, inviting guests to enjoy the natural beauty and serenity of the surroundings.

Villa in El Cope, Penonome

4.92 out of 5 average rating, 181 reviews

Mountain retreat

Our beautiful, modern, comfortable house is designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and also a base to explore the area which is in a beautiful part of Panama near a cloud forest national park with amazing hiking to waterfalls and local communities. The house is large, sleeping 12, within 17 acres of forest with rivers for swimming. We can arrange tours and hosted retreats for yoga, cooking and more.

The outdoor area features a private pool, illuminated with soothing blue tones, alongside sun loungers partially submerged in the water. Soft lighting highlights the modern architecture of the house and its spacious terrace, providing a relaxing ambiance under the evening sky.

Home in Vista Mar Golf, Beach & Marina

4.89 out of 5 average rating, 256 reviews

Luxurious Beach House - Private Pool Golf & Marina

Vista Mar Golf, Beach & Marina is a gated community with private security, with direct access to a state of the art golf course designed by J. Michael Poellot. It also has marina, heliport, tennis courts, direct private beach access, bars and restaurants. The house comes with an outdoor private pool & hot tub, also a amazing private outdoor kitchen, and an amazing sea view with spectacular sunrises and sunsets. any inquiry please contact 66168596

Top guest favorite

A private pool area is framed by lush tropical plants and trees, with lounge chairs situated nearby. The pool’s clear blue water reflects the surrounding greenery and the structure in the background, which includes a covered patio for relaxation.

Home in Las Colinas de Caceres de Arraijan

4.98 out of 5 average rating, 215 reviews

Tropical Haven with Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

An inviting infinity pool is positioned on a spacious patio, overlooking a sweeping mountain view. Two lounge chairs are arranged on the deck, facing the water, while lush greenery and colorful blooms enhance the serene environment surrounding the pool area.

Cottage in Altos del Maria

4.94 out of 5 average rating, 161 reviews

Mountain Cottage with Heated Pool and Amazing View

Mountain Cottage, with spectacular views of the Altos del María Mountains, perfect for relaxing or spending time with the family. It features a heated infinity pool, spacious outdoor spaces, Smart TV and A/C in all rooms and living room, Wi-Fi throughout the property, and is fully equipped. Includes Prime Video service. It also has a fire pit and a gas BBQ. Complimentary late checkout is available for rentals departing on Sundays.

Top guest favorite

A bright dining area features a round wooden table surrounded by six turquoise chairs. Large windows allow natural light to fill the space, showcasing a cozy atmosphere. A wooden dresser and potted plants add touches of comfort. Arched openings lead to other rooms.

Home in El Valle de Antón

4.95 out of 5 average rating, 163 reviews

Rustic family mountain home - 5 min walk to town!

Rustic family home with exquisitely landscaped garden complete with bridge over natural stream. Outdoor chill out space with barbecue and terrace under roof with hammocks on one side of the house, and a pergola with lounge area and gas grill on opposite side of the house. Centrally located to main attractions, only a 7 minute walk to the main market. Peaceful, relaxing refuge surrounded by views of nature and the cloud forest.

The outdoor area features a large swimming pool surrounded by lounge chairs, with a separate jacuzzi nearby. Inside, a game room comprises a pool table and a ping pong table, with expansive glass doors allowing natural light and views of the greenery.

Villa in Costa Esmeralda

4.97 out of 5 average rating, 104 reviews

#1 Villa with a swimming pool, jacuzzi, pool table, and ping pong.

Spectacular villa a few minutes from the beach by car, super spacious, ideal to share with family, friends or corporate meetings. The property is full of surprises and with many things to do including its swimming pool, jacuzzi, pool table, ping pong table, domino table, hammocks, large green areas, gas BBQ, variety of board games and a fully equipped kitchen.

A spacious living area features large glass doors opening to a private terrace, allowing natural light to fill the room. A comfortable sectional sofa and stylish dining table are complemented by a large television on an accent wall. Tropical plants enhance the inviting ambiance.

Condo in Buenaventura, El Chirú

4.92 out of 5 average rating, 137 reviews

Modern | Steps to Beach Club & Shops | Sleeps 10

★ A Proper Rents Experience ★ • Beautiful design • Excellent location • Steps to the La Mansa Beach Club! • Spacious & luxurious • Luxury Bedding • 75 inches TV • Beautiful views! • Half a block from restaurants & convenience store! • Fully equipped • High speed internet • Buenaventura, best luxury beach resort in Panama

Vacation rentals for every style

Get the amount of space that is right for you

Villas

Luxurious estates for the ultimate escape

Cottages

Quaint homes, peaceful surroundings

Cabins

Kick off your hiking boots at these rustic lodgings

Popular amenities for Panama mansion rentals

Free parking on premises

Air conditioning

Luxury mansion rentals

Top guest favorite

A sparkling blue pool with a circular spa features surrounding lounge chairs shaded by tall umbrellas. Lush greenery is visible in the background, enhancing the tranquil ambiance. Light reflects off the water, creating an inviting setting for relaxation.

Villa in Rio Hato

5 out of 5 average rating, 12 reviews

Villa Solara 5 - Luxury 5 Bedroom Pool Villa

An aerial view captures the expansive property with a bright red-roofed house surrounded by lush greenery and palm trees. The inviting pool reflects the sunset over the ocean, offering a serene ambiance. The beach is in close proximity, enhancing the tranquil coastal setting.

Villa in Las Lajas

4.86 out of 5 average rating, 42 reviews

Beach House Where Emy

Top guest favorite

A bright living area features large glass doors that provide a panoramic view of the beach and ocean. A spacious sectional sofa is positioned near natural light, complemented by a wooden dining table. Elegant decor elements include woven light fixtures and fresh greenery.

Condo in Maria Chiquita

4.98 out of 5 average rating, 63 reviews

Playa Escondida Lux Beachfront Haven:Oceanview Apt

A two-story house with a distinctive triangular roof and a welcoming entrance is surrounded by lush greenery. The exterior features a mix of stone and white walls, and landscaped gardens with colorful flowers enhance the appeal of the property.

Villa in Boquete

5 out of 5 average rating, 9 reviews

The perfect weather in Finca San José, Boquete

A lakeside gazebo with a tiled roof is situated among lush greenery. Kayaks in vibrant colors await on a wooden dock extending over the water. Comfortable seating is arranged on the platform, providing a serene space for relaxation by the lake.

Cottage in Panama City

5 out of 5 average rating, 21 reviews

Hacienda La Perezosa in Cerro Azul

An aerial view of a spacious villa is displayed, featuring a large terrace with loungers positioned around a pool. The structure boasts a modern design with a red-tiled roof and expansive glass windows, overlooking lush greenery and rolling hills.

Villa in Mariato

4.8 out of 5 average rating, 20 reviews

Villa Papagayo, Morrillo Beach, Veraguas

Top guest favorite

A spacious living area features a comfortable sectional sofa adorned with decorative pillows. Large windows provide a view of the ocean, while a dining table is visible in the background. Stylish light fixtures hang from the ceiling, adding to the open and airy feel.

Condo in Maria Chiquita

5 out of 5 average rating, 49 reviews

Playa Escondida. Apartment with ocean views.

A tranquil outdoor seating area features a light-colored sofa positioned beside a swimming pool. Lush palm trees are visible in the background, along with a marina and waterfront. The sky is clear, creating an inviting atmosphere for relaxation.

Apartment in Maria Chiquita

5 out of 5 average rating, 24 reviews

Ocean front apartment at Playa Escondida

Pet-friendly mansion rentals

Lush palm trees are featured along a well-maintained pathway leading to the beach. Green coconuts hang among the fronds, while vibrant greenery and white stone walls add a fresh touch. The sandy shore is visible in the background, framed by a clear blue sky.

Vacation home in San Carlos

4.92 out of 5 average rating, 51 reviews

Welcome to our house in Playa Corona

An inviting outdoor kitchen area equipped with a grill and dining set overlooks a lush garden. A cozy indoor living space features a plush sofa and a large TV. The private pool, framed by lounge chairs and greenery, offers a tranquil oasis for relaxation.

Condo in El Chirú

4.91 out of 5 average rating, 47 reviews

Laguna Fun and Sun: Your Escape Awaits

The estate features a two-story structure with orange and stone accents, surrounded by lush greenery. A covered porch extends along the front, providing a shaded spot to enjoy nature. The backdrop of rolling hills adds to the serene environment of this secluded retreat.

Villa in El Valle de Antón

4.89 out of 5 average rating, 47 reviews

Quinta El Bosque

A hammock is suspended under a covered terrace, overlooking a serene beach. Yellow chairs are positioned nearby on a wooden deck, complemented by a coastal view featuring calm blue waters and a clear sky. The scene is tranquil and inviting for relaxation.

Chalet in Juan Hombron

5 out of 5 average rating, 4 reviews

Charming house with beach access

An inviting seating area features a modern sectional sofa with plush cushions arranged in an L-shape. A wooden coffee table rests in front, complemented by indoor plants placed nearby, enhancing the tranquil space.

Home in Panamá

4.86 out of 5 average rating, 58 reviews

Wonderful House with Terrace and Ocean View

Top guest favorite

A serene pool area is surrounded by lush greenery and vibrant purple bougainvillea. An inviting swimming pool is framed by a tiled patio, with a shaded seating area visible in the background. Soft natural light filters through the foliage, creating a tranquil outdoor setting.

Cottage in Panamá

5 out of 5 average rating, 18 reviews

Cerro Azul, Country House with Heated Pool.

A wooden deck surrounds a tranquil pool, complemented by a large umbrella providing shade. Two lounge chairs are positioned nearby, while a round dining table with multiple chairs is visible, set in an inviting outdoor space surrounded by lush greenery.

Home in Playa Bluff

4.89 out of 5 average rating, 46 reviews

Jungle House 100m from the beach

Top guest favorite

Home in Rio Hato

4.98 out of 5 average rating, 126 reviews

Spacious Vacation Home in a Tourist Area

Mansion rentals with a pool

Home in La Ermita

4.83 out of 5 average rating, 12 reviews

2 beachfront houses, spectacular private beach.

An outdoor pool area is framed by well-maintained gardens and palm trees, illuminated by warm lights. Multiple lounge beds under a shaded pergola provide relaxation spots. The pool features a circular design, surrounded by landscaped greenery, creating a serene atmosphere at dusk.

Condo in Buenaventura, El Chirú

4.97 out of 5 average rating, 127 reviews

Stylish & Quiet ~ Breathtaking Laguna Views ~Pool

A view showcasing a lush garden surrounded by palm trees, leading to a swimming pool area. Sun loungers and umbrellas are positioned for relaxation, with the beach and ocean visible in the distance, providing a serene, coastal atmosphere.

Apartment in San Carlos

4.86 out of 5 average rating, 7 reviews

Beach Front 4 bed 4.5 Bath Ocean

A serene outdoor area is showcased, featuring a swimming pool surrounded by well-maintained grass and a decorative fountain in the foreground. Lounge chairs are positioned near the pool, while lush greenery offers a sense of privacy.

Home in Panama City

4.95 out of 5 average rating, 41 reviews

Nice duplex house with a swimming pool.

Villa in Rio Hato

4.86 out of 5 average rating, 44 reviews

La Casa de las Uvas, an oasis with ocean views

A large outdoor space features a kidney-shaped swimming pool with a connected hot tub, surrounded by lush greenery and palm trees. The pool area is bordered by vibrant stone pathways and a small building with a clay tile roof in the background.

4.79 out of 5 average rating, 96 reviews

Villa GiGi - Beach Home Panama Santa Clara

Top guest favorite

A well-lit bedroom features a spacious bed with white linens and colorful accent pillows. Two nightstands with green lamps are positioned beside the bed. Natural light enters through a window with sheer curtains, and a ceiling fan is mounted above, enhancing ventilation.

Condo in El Chirú

4.97 out of 5 average rating, 33 reviews

Buenaventura | Luxury Beach Apartment | Panama

A serene outdoor space features a tranquil water fountain set against a backdrop of palm trees. The fountain's gentle spray is visible, with paved walkways leading toward the water's edge. Comfortable seating arrangements are situated nearby, enhancing the open atmosphere.

Condo in El Chirú

4.89 out of 5 average rating, 148 reviews

Beach apartment in BUENAVENTURA

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