Hotel vacation rentals in Panama

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Top-rated hotel rentals in Panama

Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.

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Guest favorite

A spacious sitting area is framed by large panoramic windows, offering sweeping views of lush greenery and distant mountains. The modern furnishings include two light-colored sofas and a glass coffee table, complementing the bright atmosphere created by natural light.

Hotel room in Boquete

4.97 out of 5 average rating, 39 reviews

La Residencia - Suite Bella Vista

This Impressive, extravagant, light flooded Suite with breathtaking view to the Baru Volcano is located just a 10-minute walk from the center of Boquete. Modern and contemporary style with a high sense of detail, located in the second floor of an extraordinary mansion. Luxurious 80m² suite (King-Size/Orthopedic mattress) with spacius private bathroom, huge walkin closet, private full equipped kitchenette, panoramic window, 2 air conditioners, free parking, fast Wifi, cable TV, Netflix, Spotify.

Guest favorite

A spacious bedroom features a wooden platform bed with a blue patterned mattress. Large glass doors open to a private patio, surrounded by lush greenery. Two chairs are positioned on the terrace, and a colorful framed artwork adorns the wall near a window.

Hotel room in PA

4.9 out of 5 average rating, 29 reviews

Treetop views of the Pacific in a boutique cabaña

No detail left unnoticed…our boutique cabañas are nestled in jungle gardens with private porches overlooking the Pacific, hammocks for lounging, indoor/outdoor concept bathrooms, stunning hardwood floors, and custom-made furniture. Each of our three cabañas has its own unique charm where comfort meets luxury. We are steps from the beach and minutes from consistent surf breaks and community yoga classes. A shared kitchen is on site, with individual cooking utensils provided for each room.

Guest favorite

A light and airy room is shown with large glass doors leading to a lush outdoor area. A wide-brimmed hat rests on a bed, while a figure stands at the door, showcasing a flowy floral skirt and a simple top amid greenery.

Hotel room in PA

4.91 out of 5 average rating, 34 reviews

Villa Coco King Room

Villa Coco is a beautiful boutique hotel in Santa Catalina, only footsteps away of the world known surf break “La Punta” and Unesco world heritage Coiba island. The carefully designed cabañas, provide a space of tranquility and a sense of timelessness. Unwind in the hammocks and canvas chairs on your private terrace, dwell on reading your favorite book or sip on a cool drink from the bar. Our Restaurant “Ai Mamita” offers different kinds of meat, fresh seafood and other tasty delights.

Top guest favorite

The bungalow features a screened-in porch, framed by lush greenery and colorful plants. Warm sunlight casts shadows across the wooden structure, creating a serene and inviting atmosphere amidst the surrounding foliage.

Hotel room in Bastimentos Island

4.95 out of 5 average rating, 64 reviews

Casa Florecer- bungalow at the edge of the sea

Welcome to Casa Florecer, a bungalow at the edge of the sea. Your space is simple and elegant. A studio apartment with plenty of room to enjoy a quiet & peaceful time on the island. The bungalow boasts a screened in porch, gorgeous views, and pristine coral reef for your front yard. All stays include a locally sourced vegetarian breakfast served in our over the water eatery, Juntos. For fun closer to home: we have snorkel gear, paddle boards, and yoga mats available for your enjoyment.

Guest favorite

A shared swimming pool is surrounded by tropical palm trees and lush greenery. Two vibrant bean bag chairs are placed beside the pool on a wooden deck, providing a relaxing spot to enjoy the ocean view in the distance during twilight.

Private room in Bastimentos Island

4.94 out of 5 average rating, 47 reviews

The Firefly B&B oceanfront bungalow w/ pool

Our b&b is a little off the beaten path but we love it that way. Listing is for one of our two private, oceanfront bungalows. We can let you know which one is available at time of booking. We are an eco lodge & describe our vibe as "hip, rustic beach house". Our rooms are fan cooled & have in room safes. Pool is shared by all five rooms. Breakfast is included. If a "resort" or 4 star place is your vibe, we are probably not for you :) We accept guests 15 and up.

Superhost

A round wooden dining table is set for four, surrounded by light-colored chairs. A chandelier hangs above, casting a warm glow. Light enters through open doors, highlighting wall art and plants, creating a welcoming dining space.

Casa particular in Dolega District

5 out of 5 average rating, 3 reviews

Wanakaset Forest Haven 2BR, River & shared Pool

Casa Quetzal is a serene 2-bedroom retreat nestled in the lush forest of Wanakaset Panama, perfect for up to 4 guests. With its open-plan living space, modern bathrooms, and fully equipped kitchen, it offers comfort in a natural setting. Relax on the private terrace or enjoy the shared pool, just a short walk away. Surrounded by rivers and tropical greenery, it’s an ideal escape for nature lovers seeking tranquility and a peaceful getaway.

Guest favorite

The wooden cabin features a thatched roof and multiple windows, allowing for natural light. A landscaped entrance path leads to a spacious deck with wooden railings. Outdoor lighting creates a warm ambiance in the evening, showcasing the surrounding greenery.

Private room in Playa Venao

5 out of 5 average rating, 5 reviews

Dos Mares Venao Village - Bungalow

Desconecta de tu rutina y disfruta de la naturaleza. Nuestras Cabañas son amplias, cómodas, con mucho estilo y de alta calidad. Con 1 habitaciones con cama King, una habitación con dos camas twin, sala y cocina hay espacio para toda la familia. Además tenemos ducha externa, televisión, y una terraza amplia. En nuestro bar puedes disfrutar de los mejores desayunos. Si deseas también te lo llevamos directo a tu cabaña - como lo deseas!

Superhost

The villa is situated amidst lush greenery, showcasing a modern design that blends with the surrounding jungle. Spacious outdoor areas are visible, with seating arrangements under the shade of trees, inviting a relaxed atmosphere for guests to enjoy their surroundings.

Hotel room in Cambutal

4.94 out of 5 average rating, 18 reviews

Boutique Inn_The Hill 2_Private Entry_Tripple_+16

The Hill Panama, our Boutique Inn Adult Only (16+) is proud to be featured on Architectural Digest Magazine, located in the heart of enchanted Cambutal Beach, just a 5 five-minute walk to the beach, surrounded by several surf spots, balance between mountain and sea, hidden amongst the jungle canopy. This listed Room 2 was designed as a boutique hotel room with separated private entry and communal kitchen.

Guest favorite

A serene outdoor seating area is featured on a wooden dock above the water, illuminated by soft string lights. Guests are seen relaxing under thatched umbrellas, with a picturesque sunset reflecting on the calm surface of the sea.

Hotel room in Bocas del Toro

4.99 out of 5 average rating, 68 reviews

BarrBra / Double Bed / Priv. Bath. / Ac

- house built right over the Caribbean sea - bedroom with double sized bed & balcony - private bathroom (hot water shower) - air conditioning included - a la carte breakfast included (between 8 - 9:30 a.m.) - guest kitchen - sunset orientated (yes, we're facing west! :)) - ocean access from our private dock - in-house kayak, bike and snorkel gear rentals - gay-friendly place

A wooden cabana sits elevated on stilts, topped with a thatched roof. Steps lead up to the open side, revealing a cozy interior. Surrounding foliage includes a variety of trees and plants, contributing to the natural setting of the community.

Nature lodge in Darién Province

4.7 out of 5 average rating, 20 reviews

La Chunga

La Chunga is in a difficult access indigenous community without electricity or roads. Come see this gem of a community and the indigenous way of life. You’ll love this place because of the nature walks, the wildlife, the gastronomy, and the people. We have a number of guided tours and adventures. My place is good for adventurers trying to see something new and exciting.

Top guest favorite

A double bed with crisp white linens is positioned against a light-colored wall. Air conditioning is mounted above, providing comfort. A handmade garment rack is visible to the side, along with a decorative piece and a doorway leading outside.

Private room in Santa Catalina

4.95 out of 5 average rating, 20 reviews

Casa Manila Doble Room with terrace

Welcome to our calm place in front of the ocean. The place is perfect for relaxing on your private terrace and offers breathtaking views of the pacific ocean. In our freshly renovated rooms with A/C you can enjoy a cold breeze after a sunny day. At the end of the day you will be surprised by the best sunset in Santa Catalina.

Top guest favorite

A private dock extends over the water, featuring two lounge chairs positioned for relaxation. A potted plant adds a touch of greenery. The scenery presents a clear view of the water and distant land under a bright blue sky.

Casa particular in Bocas del Toro

4.96 out of 5 average rating, 95 reviews

Urania House

Casa con hermosa vista al mar en donde puedes disfrutar de bellos atardeceres mientras se mece en las hamacas del balcon. La casa consta de tres amplias habitaciones, dos baños con agua caliente, Sala, comedor, cosina, terraza y balcon. La casa esta completamente equipada y amueblada para su comfort; TV cable, Internet-wifi.