
Guesthouse vacation rentals in Mesa
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Mesa
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Private yard - Short walk to Mill - Historic House
Reliably operated by a top AZ Superhost with 2,250+ 5 star stays. A TRUE find! Best location in Tempe - walkable to downtown, bars and restaurants on Mill, ASU (1.5 miles), Tempe Beach Park, etc. Hidden-away historic guest house with a private yard (and even a secret outdoor shower). Professionally designed and setup with guest comfort in mind - everything is here for you - premium bed, a dedicated workstation, fast speed WiFi, fully stocked kitchen, an outdoor seating space with bistro lights.

Resort-living in private Studio @ Villa Paradiso
* Private, bright guesthouse immersed in a peaceful oasis of lush landscaping. The guesthouse is right in front of our swimming pool. * Fully remodeled: Kitchen, TV, Wifi, Nespresso & more. * Central location: 10 mins from Old Town Scottsdale, ASU, Sky Harbor Airport, Spring Training & more. Check out my profile for two Luxury B&B suite listings in the main house. Private bedroom & bath, full access to living areas + breakfast. Ask about photoshoots or events across the various property areas.

Luxury Modern Executive Retreat
Northeast Mesa location close to Tonto National Forest, the Salt River and Saguaro lake. 5 minutes from Boeing, Nammo Talley or MD Helicopter. 25 minutes from downtown Phoenix or Scottsdale. Nestled at the base of the Goldfield mountains. Contemporary open floor plan with modern design. Private entrance and single parking spot in front of the main house. Fast WiFi. Roku and cable TV. Beautiful, quiet neighborhood close to city amenities as well as biking and hiking trails. TPT# 21558238

Private, Convenient Studio Apartment
Discover the perfect blend of location and comfort in our newly renovated studio apartment. Nestled centrally between Mesa, Scottsdale, and Tempe, you're at the heart of abundant dining choices, shopping convenience, and grocery store accessibility. Just 15 minutes from Sky Harbor and a swift 30 minutes from Mesa Gateway, your travels are a breeze. Enjoy total privacy with your exclusive entrance, ensuring a tranquil, personal escape in the midst of the city's best offerings.

Detached Guesthouse | Driveway Park | Full Kitchen
Enjoy our newly remodeled and professionally designed 1 bed, 1 bath private guesthouse. The stylish and cozy suite includes a full kitchen with brand new appliances, a work space, living room, and bedroom with a closet and ensuite bathroom. It is located just 15 mins away from major destinations, such as ASU, Sky Harbor International Airport, and fun attractions. We offer free parking on the property, in addition to wi-fi, Roku TV and toiletries. We would love to host you!

Cottage
Have you ever wanted to try a tiny house? The Casita is your chance! The Casita is a sparkling clean, small studio that has everything you need for your stay! The Casita is nicely located to Route 60 2miles. then to 101, 202 and I10. Mesa Convention center, Mesa Arts Center and Mesa Amphitheatre: 2 miles. ASU 8 miles. MCC 2 miles. Phoenix 19 miles. and Scottsdale 13 mi. Also many casinos, golf courses and hiking trails. Come enjoy the East Valley!

Saddle Lane Casita, North Central Phoenix, AZ
This hidden gem is centrally located on N Mountain in N Central Phoenix. 20 min to downtown Phx, 20 min to W. Valley, Scottsdale, Tempe, and Phoenix Int'l Airport. Our Casita features 1 room with a king bed, 1 bathroom, and a patio that faces west to enjoy Arizona's beautiful sunsets. We have a very steep driveway, and a full flight of stairs to the casita. If you have trouble walking or have knee and/or breathing problems, this is not the place for you.

Entire Suite: Private and Cozy Clark House Casita
Feel right at home by staying at our quaint and unique 350 sq ft casita! Our casita has a full bathroom, and a kitchenette. Catch up on your favorite shows in the living room with our HD smart TV, or watch a movie while cozied up on our comfy queen size bed using the second tv in the bedroom, or relax in the shaded patio surrounded by mature trees. No smoking or vaping inside or outside of the property.

Mesa Casita with King Bed
Casita with a king size bed and kitchenette located in a quiet Mesa neighborhood. The room is a dedicated Airbnb space in a separate building from the main house with it’s own entrance, private bath, and kitchenette perfect for a quick breakfast or a bite to eat. We are minutes from local freeways. A 15 min drive to Scottsdale, Tempe, Chandler, and Gilbert.

Orchard Cottage, Heated Pool and Hot Tub
Beautiful private self contained suite with a large heated pool and hot tub. Very private and far away from other living areas. Great fast internet, AC is new and works great (important in Arizona) and the bathroom shower is amazing. Lots of beautiful sitting spaces, sun or shade, relax at the pool or just hang out and read on the large hammocks.

The White Barn @ Freedom Farms
Kick off your boots and relax in this calm, stylish, private guest house on Freedom Farms! Explore the natural swimming pond on the property, venture out to the Sonoran desert for a nature hike, tube down the salt river or mountain bike in Usery! You'll find our location close to the city but not in the city.

La Cabra Casita: Poolside Oasis on an Urban Farm
Enjoy an experience unlike any other at our mini ranch in the heart of Chandler. After a day of sunshine in the beautiful Sonoran desert, retreat to your private La Cabra Casita. Relax by the pool, grill up some dinner, feed the goats and alpacas, and in the morning enjoy some fresh duck and chicken eggs.
Popular amenities for Mesa guesthouse rentals
Family-friendly guest house rentals

Private Guest Studio in the Country

Detached, Private, Clean & Safe Guesthouse with Large Patio

Sanitized Spacious Desert Getaway

Downtown Casita w/ Pool (Close to Airport)

Coronado Private Casita (Private House)

Beautiful Private Guesthouse on Over 1 Acre!

Private Casita w/ Pool* & BBQ in Historic Melrose

Private Guest House of Queen Creek
Guest house rentals with a patio

Sunshine Studio! Phx/Scottsdale border!

Ruby's Hideaway, a historic red brick studio.

Cozy casita in a beautiful setting

Charming & spacious Casita! Like home only better!

Spacious Midtown guesthouse with full privacy

Your favorite PHX guesthouse!

Zen Modern Casita w/ Private Pool + King Bed

Entire Private Guest House with King Master
Guest house rentals with a washer and dryer

Centrally Located Renovated Guest House

NEW Stylishly Designed Casita Steps from DTPHX

Downtown Phx | Private Guesthouse & Parking

Private and Quiet - 1 bdrm/1 bath Casita

Enchanting Ahwatukee Secret Casita

Spacious Studio in Uptown Historic Neighborhood

DARK HOUSE | private, modern Spanish casita

Cozy Clark Casita
When is the best time to visit Mesa?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $101 | $114 | $119 | $96 | $88 | $83 | $77 | $75 | $83 | $94 | $97 | $95 |
| Avg. temp | 57°F | 60°F | 66°F | 73°F | 82°F | 91°F | 95°F | 94°F | 89°F | 77°F | 65°F | 56°F |
Quick stats about guesthouse rentals in Mesa

Total vacation rentals
Explore 150 vacation rentals in Mesa

Nightly prices starting at
Mesa vacation rentals start at $30 per night before taxes and fees

Verified guest reviews
Over 12,060 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Vacation rentals with a pool
40 properties feature pools

Rentals with dedicated workspaces
70 properties have a dedicated workspace

Wi-Fi availability
150 of Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mesa rentals

4.9 Average rating
Mesa stays are highly rated by guests—averaging 4.9 out of 5!

Nearby attractions
Mesa's top spots, include Sloan Park, Golfland Sunsplash, and Hohokam Stadium
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- Lake Pleasant Regional Park
- Phoenix Convention Center
- Chase Field
- Grand Canyon University Championship Golf Course
- Tempe Beach Park
- TPC Scottsdale - Champions Course
- Arizona Grand Golf Course
- Grayhawk Golf Club
- The Westin Kierland Golf Club
- Salt River Fields at Talking Stick
- WestWorld of Scottsdale
- Sloan Park
- Salt River Tubing
- Peoria Sports Complex
- Dobson Ranch Golf Course
- Hurricane Harbor Phoenix
- We-Ko-Pa Golf Club
- Ocotillo Golf Club
- Surprise Stadium
- Red Mountain Ranch Country Club
- Seville Golf & Country Club
- Scottsdale Stadium
- Papago Park
- Trilogy Golf Club at Power Ranch
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