Some info has been automatically translated. Show original language

Guesthouse vacation rentals in Mesa

Find and book unique guesthouse rentals on Airbnb

0 of 0 items showing
1 of 3 pages

Popular amenities for Mesa guesthouse rentals

Family-friendly guest house rentals

Superhost
Guesthouse in Camelback East
4.86 out of 5 average rating, 550 reviews

Architectural Dream Guest House

MIcheleRating, 5 stars1 week ago
What a sweet hideaway amount some beautiful, large Estates. We even found a house down the street built by Frank Lloyd Wright. Very guarded but interesting! Clean and modern. Beautiful landscape.
Guest favorite
Guesthouse in Camelback East
4.93 out of 5 average rating, 1,370 reviews

Centrally Located Renovated Guest House

GeoffRating, 5 stars6 days ago
Shaayna's place was perfect for everything we needed, not too much but just perfect for our trip. Shaayna was quick to respond on any question we had. We'll definitely stay here again.
Guest favorite
Guesthouse in Paradise Valley Village
4.91 out of 5 average rating, 685 reviews

Scottsdale guest suite

Erin GraceRating, 5 stars1 week ago
We are repeat guests and always appreciate the comfortable accommodations, quiet of the neighborhood and excellent location being so close to all the amenities of Scottsdale/Paradise Valley.
Guest favorite
Guesthouse in Gilbert
4.96 out of 5 average rating, 306 reviews

Two Bedroom, clean guest house in Gilbert

ChristiRating, 5 stars1 month ago
The house was very nice, clean and had the basics amenities. We had a short stay, but everything we needed was there. Beds were super comfy (we only used the two larger ones), and towels were nice too. We brought our own coffee, but there were coffee filters and a coffee pot available. We really enjoyed it and would stay again! No issues at all.
Top guest favorite
Guesthouse in Camelback East
4.97 out of 5 average rating, 445 reviews

The Cozy Container with pool & gym

KathleenRating, 5 stars3 weeks ago
Melissa and Josh responded quickly when we arrived and did not know where to park. The Air BnB is in a neighborhood just off the two major freeways and just north of downtown Phoenix…so it’s a great location. The unit is just off the family’s backyard and is in a shady area of the yard….very pleasant. The bed was super comfortable with lights on each side of the beds. This is important to myself/husband as we like to read in bed. All together a great place.
Top guest favorite
Guesthouse in Ahwatukee Foothills
4.98 out of 5 average rating, 1,003 reviews

Boutique Hotel Style Guest House

CindyRating, 5 stars1 day ago
Phil greeted me by the entrance to welcome me. He wanted to make sure I got inside because the door is a little bit hard to open. The casita is beyond clean. I brought Lysol wipes because I am a nut about clean. I didn’t need to use any. The little extras they provide are ABSOLUTELY delightful!! Snacks, coffee, wine, water and chocolate!! What more could you ask for?? Thank you for sharing your casita!
Top guest favorite
Guesthouse in Central City
4.97 out of 5 average rating, 192 reviews

Downtown Phoenix Neighborhood Guest House.

NinaRating, 5 stars3 weeks ago
What a gem of a space! Beautiful, peaceful and had everything I needed. Very gracious and helpful hosts and the artwork in the unit was wonderful. I highly recommend it.
Guest favorite
Guesthouse in Encanto
4.91 out of 5 average rating, 187 reviews

Stunning Spanish Modern Guest House with Pool

JohnRating, 5 stars2 weeks ago
Great place for a short stay. Thank you for allowing us to stay, we really enjoyed our visit.

Guest house rentals with a patio

Top guest favorite
Guesthouse in Gold Canyon
4.98 out of 5 average rating, 44 reviews

Pat's Place

AlastairRating, 5 stars1 week ago
Our second visit to Pats place. The setting is truly wonderful. On the edge of the wilderness. You can walk directly from the house. Yet close to all the usual amenities as well. Very comfortable inside and lovely sitting outside looking at the mountains and watching the numerous birds.
Guest favorite
Guesthouse in Scottsdale
4.93 out of 5 average rating, 120 reviews

Scottsdale Oasis

GeoffRating, 5 stars2 months ago
Wes and Kristen are the best hosts! We had an unfortunate situation that caused us to delay our arrival by 24 hours and they accommodated the change without question, this was a huge stress reliever for us. The guest house was perfect for us and the hosts offer tons of amenities (though we didn’t use them). The house was easy to find, in a very convenient location, and had everything we needed. The bed and pillows were comfortable and despite the highway being just over the wall/fence, you can barely hear it inside. We will certainly look to book with Wes and Kristen on our next trip to Phoenix!
Top guest favorite
Guesthouse in South Mountain
5 out of 5 average rating, 20 reviews

Your Moment of Zen 1-bdrm pool house *Made for 2*

CourtneyRating, 5 stars3 weeks ago
I cannot say enough good things about this stay! Jill & Carl are wonderful they were so helpful and attentive. The place is perfect in a cute neighborhood, safe and relaxing! The place is amazing we cooked most meals there and utilized the bbq too. The roof top patio is such a nice touch too with beautiful views. Jill even went as far as making sure we had tea and coffee which was great! The only down side was it is bright in the room early but we travel with eye masks so this wasn’t a problem! Both their pool and the neighborhood pool were amazing!
Top guest favorite
Guesthouse in North Mountain
4.96 out of 5 average rating, 142 reviews

Zen Modern Casita w/ Private Pool + King Bed

JanineRating, 5 stars4 days ago
Great studio with wonderful amenities. So much packed in a small place. Pizza oven was lots of fun and the outdoor space was lovely. Centrally located for our activities.
Top guest favorite
Guesthouse in Glendale
4.94 out of 5 average rating, 210 reviews

Orchard House Cozy Pool Casita

BriannaRating, 5 stars6 days ago
Alicia was an amazing host! She was very well responsive and great hospitality! I would 100% book with her if I come back to Phoenix. Thank you Alicia! 😊
Guest favorite
Guesthouse in Mesa
5 out of 5 average rating, 9 reviews

Cottage

Linda LeeRating, 5 stars1 month ago
WOW! The unit was spotlessly clean and decorated in a lovely style that made us feel very relaxed and comfortable. We really enjoyed the large bathroom and its great shower. This rental had the most amenities of any unit we have rented. Lots of lotions and shower gels, a great hair dryer, and everything needed to make simple meals. We even had an adorable welcome gift and a large basket filled with snacks upon our arrival! The pool is large and very well maintained. Security lighting was abundant and made coming and going in the dark carefree. They have an adorable puppy named Ruby that was a lot of fun. We would definitely consider staying here again in the future. Thank you to the family for working so hard to make this an A++ experience.
Superhost
Guesthouse in North Mountain
4.75 out of 5 average rating, 8 reviews

Moon Valley Guesthouse

Wendy Rating, 5 stars1 month ago
What a clean and roomy place to stay in! Every part was impressive, from the fully stocked kitchen to the large bathroom. The large king bed was very comfortable.
Guest favorite
Guesthouse in Mesa
4.94 out of 5 average rating, 116 reviews

Private Luxury Guesthouse in Mesa

AbigailRating, 5 stars2 weeks ago
This is a perfect little vacation spot! My boyfriend and I felt right at home, her place was very clean and comfortable! She provided so much stuff for you incase you may have forgotten something for example; phone chargers or Apple Watch charger, lint roller etc. checking in was a breeze! I highly recommend staying here if you get the chance! My boyfriend and I will most definitely be staying here again! 10/10

Guest house rentals with a washer and dryer

Guest favorite
Guesthouse in Mesa
4.93 out of 5 average rating, 84 reviews

Private Guest House

LindaRating, 5 stars4 weeks ago
We enjoyed our stay here at this location. Nice neighborhood, very clean, excellent feedback when we had a question/concern! We would come back again!
Guest favorite
Guesthouse in Mesa
4.95 out of 5 average rating, 131 reviews

Hacienda one bedroom with great pool

RoyRating, 5 stars1 week ago
This facility and accommodations are above and beyond what we had expected if we ever get back into her neck of the woods we will plan our vacations around the available dates of her accommodations it was spectacular she is a wonderful host I can’t thank her enough forOutstanding accommodations for making this a spectacular vacation
Guest favorite
Guesthouse in West Phoenix
4.81 out of 5 average rating, 37 reviews

Cozy Guest Casita w/ Separate Entrance

RichardRating, 5 stars2 months ago
I’ll definitely be staying in her place next spring training.
Top guest favorite
Guesthouse in South Mountain
4.97 out of 5 average rating, 107 reviews

Hidden Oasis at South Mountain!

SierraRating, 5 stars2 weeks ago
Kim’s Casita is so perfect for a quick or extended stay for two! The back porch was our favorite part, providing a great view of the city and the beautiful mountains. We’ll definitely stay in the future if in Phoenix!
Top guest favorite
Guesthouse in South Mountain
4.93 out of 5 average rating, 339 reviews

New Casita at South Mountain

DanielRating, 5 stars4 days ago
Went to Arizona for an event so only stayed 1 night, but this place will definitely be my regular place to stay when I come back to Arizona ! Really clean and at home feeling, really quiet and perfect place right outside of the city area but not too far where you’d have to commute. Definitely would recommend to anyone looking to stay around the area.
Superhost
Guesthouse in Camelback East
4.92 out of 5 average rating, 173 reviews

Hubbell Hideaway Main House Near Downtown Phoenix

KelseyRating, 5 stars1 month ago
Clean and looks like the pictures. Oliver was very responsive. One thing to note as we could not tell this from the listing, if you are traveling with a dog - the backyard is private but there is not door from the home to access it. You have to walk out the front door and through the side fence to get to it. That was not the most ideal set up for our longer stay.
Top guest favorite
Guesthouse in Peoria
5 out of 5 average rating, 50 reviews

New Guesthouse with Garage & Gym

LukasRating, 5 stars1 month ago
We had an amazing stay at this place! The space was immaculate, stylish, and thoughtfully equipped with everything I needed to feel comfortable. The attention to detail was impressive, and I appreciated how cozy and inviting the entire place felt. phenomenal host—extremely responsive, friendly, and eager to provide helpful tips about the area. She went above and beyond to make sure I had a great experience, from the smooth check-in process to offering local recommendations that enhanced my stay. The location was perfect—situated in a safe and quiet neighborhood while still being conveniently close to downtown restaurants and attractions. It was the ideal spot to relax after a busy day of exploring. I can’t recommend this place highly enough! I’ll definitely be staying here again the next time I’m in town. Thank you, for such a memorable and enjoyable stay
Top guest favorite
Guesthouse in Encanto
4.99 out of 5 average rating, 147 reviews

DARK HOUSE | private, modern Spanish casita

MadisonRating, 5 stars2 weeks ago
Donna’s place was exactly as described and the perfect spot to stay. The bedding and couch were super comfortable, and it was a nice touch being able to swivel the TV to watch from bed. The location was also ideal—just 10–15 minutes from anywhere we wanted to go in town. Donna also gave great recommendations on food spots and things to do, which made our trip even better. We’d happily stay here again the next time we’re in Phoenix.

Quick stats about guesthouse rentals in Mesa

  • Total rentals

    140 properties

  • Nightly prices starting at

    $30 before taxes and fees

  • Total number of reviews

    11K reviews

  • Family-friendly rentals

    20 properties are a good fit for families

  • Pet-friendly rentals

    30 properties allow pets

  • Rentals with a pool

    50 properties have a pool

Destinations to explore

  1. Airbnb
  2. United States
  3. Arizona
  4. Maricopa County
  5. Mesa
  6. Guesthouse rentals