Panama vacation rentals
Book unique homes, vacation rentals, and more on Airbnb
Top-rated vacation rentals in Panama
Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama vacation rentals
Other great vacation rentals in Panama
Townhouse in Panama
4.94 out of 5 average rating, 127 reviewsUnique Historic House in Casco
Jul 28 – Aug 4
Townhouse in Panamá
4.97 out of 5 average rating, 162 reviewsCasa Casco Amigos - The Only House in Casco.
Jul 11 – 18
Apartment in Panamá
4.97 out of 5 average rating, 131 reviewsAngie’s Place Cozy n Comfy in the ❤️ of #CascoViejo
Sep 25 – Oct 2
Earthen home in playa el arenal pedasi
4.96 out of 5 average rating, 117 reviewsEarth House Pedasi Experience
Oct 4 – 11
Home in Pedasí
4.94 out of 5 average rating, 116 reviews3 min to Pedasi, 5 min to the Beach, Private Pool!
Aug 4 – 11
Home in Bocas del Toro Province
4.87 out of 5 average rating, 113 reviewsCasa Clearwater... Your Caribbean Dream
Mar 2 – 9
Apartment in Panamá
4.81 out of 5 average rating, 108 reviewsBest View In Panama! Best Located Unique Full Apt.
Nov 7 – 14
Condo in Panamá
4.81 out of 5 average rating, 122 reviewsCozy two bedroom apartment
Feb 27 – Mar 6
House rentals in Panama
Home in Altos del Maria
4.78 out of 5 average rating, 240 reviewsModern House in Altos del Maria, Panama
Jan 15 – 22
Home in El Valle de Antón
4.93 out of 5 average rating, 118 reviewsRustic family mountain home - 5 min walk to town!
Jul 16 – 23
Home in Las Colinas de Caceres de Arraijan
4.98 out of 5 average rating, 196 reviewsTropical Haven with Yoga Platform
Apr 29 – May 6
Home in Los Algarrobos
4.99 out of 5 average rating, 118 reviewsNew house! 5 min from David on the Boquete highway
Nov 28 – Dec 5
Home in El Valle de Antón
4.8 out of 5 average rating, 132 reviewsCasa Antares
Jan 12 – 19
Home in Bocas del Toro District
4.82 out of 5 average rating, 106 reviewsAmazing over the water house
Jul 4 – 11
Home in playa coronado
4.8 out of 5 average rating, 111 reviewsBeach Villa in Coronado
Nov 3 – 10
Home in Bajo Boquete
4.81 out of 5 average rating, 110 reviewsSecluded Riverfront Home - Boquete area with Pool
Nov 14 – 21
Beach house rentals in Panama
Home in contadora
4.85 out of 5 average rating, 192 reviewsvilla in counter, pearls
Sep 9 – 16
Home in Playa Venao
5.0 out of 5 average rating, 15 reviewsCasa Samambaia - sea view tropical paradise w pool
May 9 – 16
Home in Playa Bluff
5.0 out of 5 average rating, 15 reviewsJungle House 100m from the beach
Aug 16 – 23
Home in Bocas del Toro
5.0 out of 5 average rating, 9 reviewsLa Casita Barrbra BnB
Jun 26 – Jul 3
Home in Bocas Del Toro
4.96 out of 5 average rating, 90 reviewsWiona of Villa Paraiso | Beachfront Villa & Pool
Jul 15 – 22
Home in Nueva Gorgona
4.95 out of 5 average rating, 19 reviewsStylish & Beachfront in Gorgona
May 15 – 22
Home in Río Hato
4.95 out of 5 average rating, 75 reviewsSpectacular beachfront house in Buenaventura!
Jul 14 – 21
Home in Panamá
5.0 out of 5 average rating, 7 reviewsUnique 4 room house - direct access to the beach
Apr 18 – 25
Your guide to Panama
All About Panama
A narrow isthmus on the southern tip of Central America, Panama is the cultural gateway to South America and the geographical gateway between the Caribbean Sea and the Pacific Ocean. Panama City, its stunning capital city, juxtaposes old-quarter Casco Viejo against the shiny, soaring skyscrapers of the modern district — all surrounded by rolling green hills and vast blue ocean studded with tiny islands. The Metropolitan Natural Park, a wildlife refuge threaded through with hiking trails, is just 10 minutes away from downtown. And Taboga Island, a volcanic enclave featuring a rich array of plants as well as white-sand beaches, is easily reachable via a 30-minute ferry ride.
The terrain rises dramatically from white-sand Caribbean beaches to lush mountain jungles. Near the top of the country, altitude-wise, you’ll find Boquete, home to world-renowned coffee plantations, and the Quetzal Trail, one of Panama’s most scenic hiking trails. Leaving from Volcan Baru National Park, it passes through the Talamanca Mountain Range, where you’ll discover rare tropical wildlife including spider monkeys, tapir, and brightly colored frogs.
The best time to stay in a vacation rental in Panama
The lovely tropical climate makes the prospect of securing a vacation rental in Panama appealing all year long. The drier winter months are ideal for hitting the country’s hiking trails or visiting the beaches. Many of the country’s most significant religious festivals, including Carnaval and Semana Santa (Holy Week), occur in March and April. You’ll want to keep this in mind when booking your Panama house rental if you are headed to a city that hosts a big celebration.
Once Panama’s rainy season starts in May, the sunshine is interrupted with short bursts of heavy rain. It is also usually the quietest time of year for tourism, and you may find yourself alone in the country’s national parks or beaches. That all changes, of course, after the rainy season finishes in November and gorgeous, sunny weather returns.
Top things to do in Panama
Casco Viejo
As the oldest part of Panama City, settled in 1673, Casco Viejo is filled with beautifully restored French and Spanish-style buildings, with a touch of art deco flair. As you stroll down the cobblestone streets, past pastel-colored buildings housing trendy restaurants, upscale bars, and inviting coffee shops, time seems to shimmer between the 19th and 21st centuries. Explore the neighborhood during the day; return after dark for its lively nightlife.
Panama Canal
When the 51-mile Panama Canal opened in 1914, it provided a waterway through Central America and reduced the traveling distance between the Pacific and Atlantic Ocean by 8,000 miles. The impact that this had on global commerce is hard to underestimate. The Pacific mouth of the canal is 26 miles outside Panama City, making it easy to visit this engineering marvel and watch as enormous ships rise and descend through a series of locks.
Bocas Del Toro
Lying close to the border of Costa Rica, this collection of islands is Panama's most popular beach destination. Largely undeveloped, the islands are home to lush tropical rainforest. Great snorkeling and diving opportunities abound in the Isla Bastimentos National Park, which is home to a wide variety of Caribbean coral species as well as (gentle) nurse sharks, crab, and stingrays.
Destinations to explore
- Hotel rentals Panama
- Bungalow rentals Panama
- Rentals with an accessible height bed Panama
- Rentals with outdoor seating Panama
- Monthly Rentals Panama
- Villa rentals Panama
- Smoking-friendly rentals Panama
- Boutique hotel rentals Panama
- Mansion rentals Panama
- Island rentals Panama
- Rentals with a patio Panama
- Rentals with pools Panama
- Chalet rentals Panama
- Rentals with a washer and dryer Panama
- Private suite rentals Panama
- Wheelchair accessible rentals Panama
- Hostel rentals Panama
- Guesthouse rentals Panama
- Rentals with a kayak Panama
- Rentals with a fireplace Panama
- Rentals with an EV charger Panama
- Rentals with a home theater Panama
- Serviced apartment rentals Panama
- Beach house rentals Panama
- Condo rentals Panama
- Rentals with breakfast Panama
- Rentals with beach access Panama
- Family-friendly rentals Panama
- Beachfront rentals Panama
- Treehouse rentals Panama
- Waterfront rentals Panama
- Boat rentals Panama
- Kid-friendly rentals Panama
- Loft rentals Panama
- Townhouse rentals Panama
- Bed and breakfasts Panama
- Fitness-friendly rentals Panama
- Cottage rentals Panama
- Nature eco lodge rentals Panama
- Rentals with a fire pit Panama
- Vacation home rentals Panama
- House rentals Panama
- Tiny house rentals Panama
- Cabin rentals Panama
- Beach condo rentals Panama
- Farmstay rentals Panama
- Ski-in/ski-out rentals Panama
- Pet-friendly rentals Panama
- Apartment rentals Panama
- Rentals with a sauna Panama
- Rentals with a hot tub Panama
- Rentals with lake access Panama
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes