
House vacation rentals in Picayune
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Top-rated house rentals in Picayune
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Popular amenities for Picayune house rentals
House rentals with a pool

Hip Art Filled Uptown Oasis w/Heated Pool +Parking
We had a wonderful stay at Nick’s place. The property was even better than the pictures! We especially enjoyed relaxing by the pool. The location is very central making it easy to get around.

Uptown Historic Compound | Private Pool & Hot Tub
This house is iconic and so perfect for a big group stay in New Orleans! The design and detail are beautiful, the neighborhood is delightful, and the host were extremely accommodating. Highly recommend!

TulaneUniv/Pool-3 ppl + if family- No parties
If you are ok with something close to everything, but not in the middle of anything, then rent this place. It is lovely, Deborah was lovely. It was comfortable, it was easy, it was great place to spend the weekend. To be clear we were not there to party and did not want to be in middle of the French quarter. So if you are, then maybe this is not the right place for you. But we were never more than 10-15 minutes from anywhere we wanted to go, and for us it was perfect.

Spencer’s Way Beach House A with heated pool
Came to BSL for a girls’ weekend and this place was perfect! There was plenty of room for 6 of us and the heated pool and outdoor area was amazing! The house is less than 5 minutes from Main Street, so a perfect location! Would definitely stay here again!

Perfect Family Getaway off Freret w/Saltwater Pool
Prime location off Fretet st. Get place for walking entertainment and night life. Property has a nice pool and great outdoor lounging. The host is very responsive and has done a get job at making sure the place has all of the amenities that one could wish for in an airbnb. Felt more at home than other rentals i have had because literally everything there. Bonus - Massive amount of board games!

Chartres Landing | 10 Guests | Private Pool
Alleshia’s space was fantastic. We had such a great time and staying here helped shape the energy of the trip. Beds were super comfy and we appreciated the number of bathrooms. We loved laying out by the pool and being in a quiet walkable area. The toiletries provided were the cherry on top!

Relaxing Bohemian House w Heated Pool 5br|4ba
We stayed with 3 other couples and loved the house. The home is beautiful, and the space was perfect for us to be together and have our own private spaces. The heated pool and backyard was great for unwinding. Centrally located for easy access to the quarter, garden district, and other great neighborhoods. Marcia was very responsive and helpful throughout. Loved our stay!

Designer Home on Magazine | Pool and Hot Tub
This is a great house in a really nice and fun area of New Orleans, especially if you have a large group! The open living room and kitchen are great for hanging out, and the patio, hot tub, and pool were also as described. We had no issues with the hot tub heat and the pool was also plenty warm for March. The rooms were clean and well appointed, and there were plenty of towels and kitchen supplies. The house also had laundry with detergent supplied for washing bath and pool towels if you have a big group. Daniel and Lindsey were super helpful and very responsive. They were kind enough to provide us with an early check-in and Lindsey was there to make sure we got in and didn't have any issues with the house! When checkout-time arrived, they didn't ask us to do anything except walk-out which makes vacation even nicer. The location was excellent with easy walking to the Quarter and coffee house, wine bar, restuaurants, etc all very close with a block or two. Highly recommend!
Weekly house rentals

Spacious, central 4br 2ba 6 beds heated toilets
The host was very responsive! Great place to stay with family while in NOLA

Heated Pool, Hot Tub, Boat/Fish Dock, No pet fees!
Our family group of 14 had a great time here. The house was large enough to accommodate all of us without feeling crowded, there was so much for everyone to do. The kids were busy all the time with paddling in the water behind the house, basketball, ping pong, soaking in the hot tub, roasting marshmallows. The house was so well stocked with everything we might need and much more. This is a great place to stay with kids of all ages!!!

4-Bedrooms Sleeps 8! Bywater 2 stories!
Awesome host , had some bad weather but Ian was super proactive in helping. The stay was very interesting. Would book with Ian again 10/10

Value comfort and location plus gated parking gr.
Karen was an amazing host. She responded to our needs very fast and was a pleasure. The house was very nice and comfortable and in a great place to walk to restaurants and the trolly.

Palais de Pershing - Walk to Freret! Add rooms!
We had 8 people in our family and we had plenty of room for everyone. The home was very clean and spacious and exactly as described. We felt safe with the wrought iron gate on the porch that closed as well as the 24 hr surveillance. We had a wonderful stay here.

Expansive Modern Luxury Home - Streetcar Adjacent!
We had 10 people for an intimate family reunion and the house was perfect for the occasion and need. We really enjoyed all the gathering spaces, the large dining table and dining outside in the backyard. The location is great if you plan on getting around by streetcars, there were 2 stops literally a few blocks away from the house. Parking is street parking but had no problem finding space in front of the house.

Marcelin’s on Napoleon Bed & Breakfast LLC
We absolutely loved staying at Marcelin’s place! We knew there would be continental breakfast options but were blown away at what was actually there. We had plenty of space for our group of 7 and the space was beautiful. It’s about a mile walk to the St Charles Street Car and like 2 minute walk to 2 different bus stops. CVS and Walgreens are within 2 minutes walk as well.

A Welcoming Place
This place feels like home or a grandparents house of love. it was perfect
Private house rentals

Big Easy GEM LARGE & Spacious New Orleans Home
This is our second year in a row staying here for JazzFest. It's an easy walk to the Fairgrounds and multiple great restaurants (including Parkway!), and the Lafitte Greenway is a hidden New Orleans gem. We'll be back!

Stunning 3 bdrm. River Paradise on 7 acres!
Very unique place. We enjoyed the grounds and sitting by the fire outside. Our fur baby enjoyed exploring too. It was relaxing and peaceful, exactly what we were looking for. We also drove into nearby Covington and had a great lunch at LOLA.

Secluded Beach House with Amazing Views 5 Bedrooms
This is the third winter that we have stayed at Amy's beach house. It is by far our favorite rental property and we have stayed at several rentals over the years. The house is awesome and has everything you need for a very enjoyable and relaxing vacation. The location, 600 feet from the beach, is incredible and the beach is dog friendly which is very important for us. The area is very quiet with very little traffic even during peak hours. There are countless restaurants in the area including Waveland, Bay St. Louis, Pass Christian, Gulfport, Biloxi, Ocean Springs etc. All are very drivable. Amy is an excellent and responsive host. Mr. Billy, who provides handyman services for Amy, is wonderful and rapidly dealt with any household issues which were very minor in nature and easily resolved. We certainly very much appreciate Mr. Billy. We are planning on renting the house again for next winter. Thank you Amy for your excellent support throughout our stay.

Live like a local! - Private Guest Suite
Great home she was very nice communicated and made shore I was okay very good directions will stay here again my next visit if I can

Maison de Colette, Luxury Home with Outdoor Patio
This was a perfect stay for our group. A quick walk to the historic trolleys that take you right to the French Quarter. You can pretty much throw a rock in any direction and hit a place with good food. Overall, this spot was good for the group and met all expectations.

Oasis Steps to Beach, Pet-Friendly, Walk Downtown
location, Location, LOCATION! This place is walkable to the beach, many restaurants and lots of cute local shops. Loved the accessibility of it all. Also, super pet friendly, a fenced in yard that was perfect for my dogs. Cute sitting area out back by the fire pit and every item you would. need in the kitchen. Best shower ever in any Airbnb I've ever stayed at. Will certainly stay here again.

Biloxi Beach View Getaway
This was such a wonderful home and place to stay! We had both of our mothers travel in with us for the Christmas holiday and we couldn’t have asked for a better stay. The location is perfect - so close to the beach, shopping and the casinos. The house was so clean and had everything we needed and a great backyard for our dogs. Would definitely recommend and would look to stay here again the next time we’re in Biloxi.

Beautiful 3 bedroom 5min DriveFrom French quarter
Great overnight stay for a dance competition at the convention center. We basically only slept and showered there but all as clean and comfortable. I did wish check in had been available a little earlier but we worked around it.
Quick stats about house rentals in Picayune
Total rentals
20 properties
Nightly prices starting at
$30 before taxes and fees
Total number of reviews
260 reviews
Family-friendly rentals
10 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with dedicated workspaces
10 properties have a dedicated workspace
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- St. Louis Cemetery No. 1
- Biloxi Beach
- Tulane University
- Smoothie King Center
- Get Wet
- The National WWII Museum
- Mardi Gras World
- Mississippi Aquarium
- Saenger Theatre
- Fontainebleau State Park
- English Turn Golf & Country Club
- Fallen Oak Golf
- Buccaneer State Park
- Gulf Island National Seashore
- Louis Armstrong Park
- Harrison County Sand Beach
- Gulfport Beach, MS
- Money Hill Golf & Country Club
- Amatos Winery
- Steamboat Natchez
- Olimpic Beach
- The Beach
- Milićević Family Vineyards
- Grand Bear Golf Club
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