Vacation home rentals in Panama
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Top-rated vacation home rentals in Panama
Guests agree: these vacation home rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama vacation home rentals
Family-friendly vacation home rentals
Vacation home in Juan Gallego
4.84 out of 5 average rating, 80 reviewsPebos Reef, 12 guests, Amazing views!!
Vacation home in El Chirú
4.85 out of 5 average rating, 20 reviewsApartment in Buenaventura
Vacation home in La Pintada
4.38 out of 5 average rating, 16 reviewsLa Pintada Inn hotel completo para grupo privado
Vacation home in Panamá
Lugar encantador con alberca privada exclusiva
Vacation home rentals with a patio
Vacation home in Anton Valley
4.91 out of 5 average rating, 43 reviewsAdorable 2 bedroom home near India Dormida hiking
Vacation home in Rio Hato
4.83 out of 5 average rating, 6 reviewsOcean view studio Town Center Playa Blanca Rio Hat
Vacation home in Volcán
4.82 out of 5 average rating, 33 reviewsHermosa cabaña con balcón
Vacation home in Bocas del Toro
4.58 out of 5 average rating, 40 reviewsPrivate Luxury Over the Water Bungalow
Vacation home in Maria Chiquita
5.0 out of 5 average rating, 21 reviewsPlaya Escondida, Caribe Depa para 8 pax
Vacation home in San Carlos
5.0 out of 5 average rating, 7 reviewsEspectacular apto de playa de tres recámaras
Vacation home in Maria Chiquita
4.95 out of 5 average rating, 21 reviewsPlaya Escondida, Apt con Espectacular Vista al Mar
Vacation home in San Carlos
4.87 out of 5 average rating, 31 reviewsBienvenidos a nuestra casa de Playa Corona
Vacation home rentals with a washer and dryer
Vacation home in Bajo Boquete
4.83 out of 5 average rating, 48 reviewsVilla Alejandro - Suite Jardin with balcony
Vacation home in Arraiján
4.79 out of 5 average rating, 47 reviewsApartamento En Club De Playa, Con Piscina y BBQ
Vacation home in Playa Blanca Rio Hato
4.79 out of 5 average rating, 28 reviewsComodo apartamento con piscina y cerca de la playa
Vacation home in Maria Chiquita
4.86 out of 5 average rating, 29 reviewsDreamy, Modern Caribbean Home at Playa Escondida
Vacation home in Chitré
4.94 out of 5 average rating, 35 reviewsCASA EdditA ° Acogedora casa en Chitré
Vacation home in Coronado
4.9 out of 5 average rating, 31 reviewsModern Beach House With Private Beach Access
Vacation home in Cambutal
4.82 out of 5 average rating, 11 reviewsTreetop 2 bedroom apartment close to the beach
Vacation home in Maria Chiquita
4.84 out of 5 average rating, 37 reviewsPlaya Escondida apto 200 mt2, 4r 4b frente al mar
Destinations to explore
- Rentals with a patio Panama
- Townhouse rentals Panama
- Rentals with a fireplace Panama
- Rentals with a sauna Panama
- Cottage rentals Panama
- Bungalow rentals Panama
- Beach condo rentals Panama
- Monthly Rentals Panama
- Rentals with a fire pit Panama
- Rentals with a home theater Panama
- Chalet rentals Panama
- Fitness-friendly rentals Panama
- Smoking-friendly rentals Panama
- Nature eco lodge rentals Panama
- Bed and breakfasts Panama
- Loft rentals Panama
- Pet-friendly rentals Panama
- Rentals with beach access Panama
- Boutique hotel rentals Panama
- Rentals with breakfast Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- Boat rentals Panama
- Rentals with pools Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Farmstay rentals Panama
- House rentals Panama
- Hotel rentals Panama
- Rentals with lake access Panama
- Villa rentals Panama
- Beach house rentals Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Rentals with a hot tub Panama
- Wheelchair accessible rentals Panama
- Treehouse rentals Panama
- Island rentals Panama
- Tiny house rentals Panama
- Family-friendly rentals Panama
- Condo rentals Panama
- Apartment rentals Panama
- Waterfront rentals Panama
- Kid-friendly rentals Panama
- Guesthouse rentals Panama
- Rentals with a washer and dryer Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Rentals with an accessible height bed Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
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- Family travel hub Tips and inspiration
- Family budget travel Get there for less
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- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes