Skip to content
Become a host
Sign up
Log in
Vacation rentals in Mark Twain Lake

Vacation rentals in Mark Twain Lake

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Mark Twain Lake

Guests agree: these stays are highly rated for location, cleanliness, and more.

Rocky Top Guesthouse on the River
SUPERHOST
Entire bungalow · 4 guests · 2 beds · 1 bath

Rocky Top Guesthouse on the RiverComplete your stay with a magnificent view of the Mississippi River from this private guesthouse sitting high on the bluff. It is located only 1.2 miles from downtown historic Hannibal where there are restaurants and shops, visitor attractions and parks.

Enjoy a getaway at Mark Twain Lake
Entire condominium · 6 guests · 2 beds · 2 baths

Enjoy a getaway at Mark Twain LakeMark Twain Lake getaway! This property is an open floorplan offering a spacious getaway at The Landing condos. It is well maintained, and has comforts of home. There are many attractions close by such as Splash Landing Water Park, swimming at Spalding Beach, Spalding Boat ramp, and Clarence Cannon Dam. Enjoy community fire pits, picnic tables, and gathering areas right outside your door. One boat parking spot is also available for guests.

Peaceful Country Cottage
SUPERHOST
Entire house · 7 guests · 4 beds · 1 bath

Peaceful Country CottageEnjoy a peaceful country view while relaxing on the front porch. This home sits on 14 acres, just off US Highway 61. Guests will see deer roaming in the yard early morning and at night. This rental accommodates families traveling with children or the couple seeking a quiet retreat. Stay here while you visit family and friends in the area. It is a short drive to Louisiana, Clarksville, Hannibal or Mark Twain Lake. (40 Min). We are about one hour from St. Louis.

Vacation rentals for every style

Get the amount of space that is right for you

  • Homes
  • Hotels
  • Unique stays

Popular amenities for Mark Twain Lake vacation rentals

  • Kitchen
  • Wifi
  • Pool
  • Free parking on premises
  • Air conditioning

Other great vacation rentals in Mark Twain Lake

  1. Entire apartment
  2. Hannibal
Farmhouse
$100 per night
  1. Entire cabin
  2. Perry
NEW! Cozy Perry Cabin - 8 Mi to Mark Twain Lake!
$78 per night
SUPERHOST
  1. Entire house
  2. Hannibal
Modern 2 Bdr House in Great Neighborhood.
$90 per night
SUPERHOST
  1. Entire house
  2. Saline Township
Home Rental One Mile from Mark Twain Lake
$115 per night
SUPERHOST
  1. Entire house
  2. Centralia
Park Side Cottage
$52 per night
SUPERHOST
  1. Private room
  2. Hannibal
Stone Hill Stables
$130 per night
SUPERHOST
  1. Entire cabin
  2. Stoutsville
Beautiful Log Cabin on 34 Acres at Mark Twain Lake
$550 per night
SUPERHOST
  1. Private room
  2. Hannibal
The Royal Suite
$169 per night
SUPERHOST
  1. Private room
  2. Hannibal
The Greek Isle
$110 per night
SUPERHOST
  1. Entire house
  2. Hannibal
Night at the Twain Museum: Luxury Hannibal Retreat
$149 per night
SUPERHOST
  1. Entire house
  2. Hannibal
Historic Victorian Mansion with a Modern Flair
$159 per night
  1. Entire house
  2. Hannibal
Prairie Style Home by Frank Lloyd Wright disciple
$189 per night

Nearby destinations