Vacation rentals in Lyon

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Top-rated vacation rentals in Lyon

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Guest favorite

A vibrant building exterior features a large mural depicting musicians and guitars. The entrance to Delta Digs is marked by an arrow, drawing attention to its location amidst the colorful artwork. Windows along the facade showcase a lively atmosphere.

Apartment in Clarksdale

4.92 out of 5 average rating, 144 reviews

Delta Digs-the place to lay it down

Delta Digs is a fabulous new vacation rental designed, built, and decorated in true Delta style by local artisans. The 425 square foot, ground level (no stairs) flat is newly constructed in the circa 1897 Clarksdale Telegraph Office at Second & Delta in the heart of the Historic District downtown. Featuring a Queen-size bed with PosturePedic mattress and Magic Fingers, hardwood floors, diner booth from a classic diner, elegant leather sofa & oversize chair, 4 foot X 5 foot custom shower with Speakman faucets, new bath and vanity, Central heating and air conditioning,refrigerator, coffee maker, microwave, HD flat screen TV with DirecTV, & stereo. 600 count 100% Cotton Sheets, Down Pillows,and 100% Cotton bath towels. We feature original artwork by many Mississippi artists (painters,photographers,designers). Location,location,location. Located across the street from Hambone Art Gallery and the Rock & Blues Museum, and around the corner from restaurants Yazoo Pass, Gradma's Pancakes, Bluesberry, Stone Pony, and Levon's Bar & Grill. Blues clubs Ground Zero Blues Club and Red's are within a 4 minute stroll. The New Roxy and the Delta Blues Museum are within 3 blocks. There is a wine and spirits shop, plus a convenience store within the block. Art gallerys, gift shops, and CatHead Records Folk Art and Blues Store are all within one block of our front door.

Guest favorite

The exterior of the home features a vibrant yellow front door, flanked by decorative plants. The brick facade and large windows provide a welcoming entrance. A well-maintained lawn surrounds the front, enhancing the inviting appearance of the property.

Home in Clarksdale

5 out of 5 average rating, 29 reviews

Delta Dream Retreat (Entire Home)

Relax with the whole family at this peaceful place to stay. we have put our heart and soul into renovating this entire home with all new appliances , bedding, furniture, mattresses, etc. It Is very modern and comfortable for families. It incl wi-fi, usb and multi movie channels every room, games, coffee, water, tea, and complimentary snacks. Only one camera[ring door bell] at the front door. Great neighbors and less than 2m from downtown Blues venues, Historical Crossroads, & eateries.

Superhost

A cozy living area features two light-colored sofas opposite each other, adorned with decorative pillows. An intricate area rug covers the floor, complementing the rustic wooden walls and high ceiling. A room divider is positioned in the background, dividing the space from the bedroom. Natural light filters through the nearby windows.

Cottage in Clarksdale

4.91 out of 5 average rating, 316 reviews

Sunflower Cottage on the River

Only a mile from historic home of the blues, Clarksdale in a gated community. The cottage sits on the banks of the Sunflower River with beautiful views of rustic woods. Out your window you might see deer, fox & other wildlife. Take a walk along the riverbank. You’ll enjoy relaxing in the comfy beds, ,enjoy privacy, the piano , & closeness to all the blues music venues. It has two fire pits, an outside grill & full kitchen. Great for couples, adventurers, business travelers , musicians ,

Guest favorite

A charming blue cottage features a gabled roof and a white front door framed by two light fixtures. Two vintage chairs are positioned on the grassy area in front, surrounded by mature trees that provide some shade.

Cottage in Clarksdale

4.84 out of 5 average rating, 165 reviews

The Gallery at Chateau Debris

Welcome to The Gallery! This one-bedroom cottage sits behind the main house. It has recently been renovated, but is decorated with vintage furnishings for personality. The cottage is equipped with a full kitchen, bedroom, bathroom, washer and dryer, & Roku TV. Your stay will be unique, as the decor has been selected from my collector's lair, and the best part is - it's all for sale! The Gallery is a live-in collectibles showroom so, contrary to the saying - you CAN take it with you!

Guest favorite

A modern kitchen area features sleek black cabinetry and a wooden countertop with bar seating for three. Stainless steel appliances, including a refrigerator and microwave, are present, along with essential kitchen tools and a coffee maker conveniently arranged.

Loft in Clarksdale

4.83 out of 5 average rating, 12 reviews

Sunflower Loft A

Welcome to The Sunflower Lofts! These modern, fully furnished apartment-style accommodations are located in the heart of downtown Clarksdale. With a coffee shop just a few doors down and all the best restaurants & music venues within walking distance, you won't even need to get in the car until you leave! We accept long and short-term guests, so stay with us for one night or a few weeks! No pets. No smoking. Quiet hours begin at 10:00 pm. We do not accept local reservations.

Guest favorite

A spacious bedroom is equipped with two queen-sized beds, each dressed in soft blue bedding. A cozy couch is positioned nearby, and decorative wall art adorns the grey walls. Natural light filters through window treatments, enhancing the inviting atmosphere.

Home in Lambert

4.91 out of 5 average rating, 22 reviews

Southern Charm

Relax with the whole family at this peaceful place to stay. You'll have three bedrooms and four queen sized beds for your enjoyment. A very spacious living/dining room area for the whole family to sit and chat. There is also two full-sized bathrooms. Also included is a screened in outdoor porch with plenty of seating. There is onsite laundry accommodations and a complete kitchen with all the ammenities.

Superhost

A living area features dark leather recliners arranged around a small coffee table. The room displays wooden accents and a staircase leading to the upper level. A hallway with artwork and natural light creates a welcoming atmosphere.

Home in Lyon

4.83 out of 5 average rating, 6 reviews

Safe Clarksdale Stay/Secluded 2600 sf barndominium

Take it easy at this unique and tranquil getaway. Enjoy beautiful sunsets and pastoral scenery while you relax in the spacious barn house. Right in the middle of Mississippi Delta farm land. Traveling for work, tourist, hunters everyone has enjoyed staying at the "Barn House." Safest place in the area to stay. Plenty of room for boats, trailers and vehicles. Stalls for horses also available.

Guest favorite

A cozy sitting area features a brown sofa and a matching armchair, both adorned with decorative cushions in blue and gold tones. A vibrant wall art piece hangs above the sofa, complemented by a stylish chandelier and soft window drapes.

Home in Mound Bayou

4.9 out of 5 average rating, 30 reviews

Come and enjoy a charming stay!

Have fun with the whole family at this stylish place. This is a beautiful historical property in a historical town. This house has a full kitchen and a washer/dryer, large smart TV, and an adorable, comfy reading area. Updated appliances for a wonderful stay in Mound Bayou, Ms. Your safety and security is very important to us, we have surveillance security cameras at all point of entry.

Guest favorite

The brick exterior of Blues Hound Flat is characterized by large glass block windows and a centrally positioned red door. Horizontal blinds cover the windows, providing a sense of privacy while allowing light to filter through. A small air conditioning unit is visible above the door.

Loft in Clarksdale

4.93 out of 5 average rating, 437 reviews

Blues Hound Flat

Blues Hound Flat sits quietly across from the historic Greyhound bus station in the center of downtown Clarksdale. Step outside, and you're in the heart of the Delta Blues, surrounded by local eateries, shops, bars, and music venues! The air itself is heavy with the traditions of the Delta. This loft-style flat features all the basic amenities one could want and solitude when needed.

Guest favorite

The living area features exposed brick walls and large windows, providing natural light. A cozy couch is complemented by two side tables and lamps on either side. A decorative coffee table enhances the inviting atmosphere of the space.

Apartment in Clarksdale

4.88 out of 5 average rating, 25 reviews

High Cotton Condo Unit D

High Cotton Condo Unit D is centrally located in heart of downtown Clarksdale with 2 bedroom, 2 baths, and a foldout couch in the living room. This unit is updated and fresh with a large living room, a modern kitchen, and great retractable windows that look out onto Delta Avenue below! Condo D has all the modern luxuries you need to make your trip to Clarksdale complete!

Guest favorite

The exterior of a single-story house is highlighted by a well-maintained lawn, framed by trees. Light-colored siding and brown shutters complement the entrance, which features a white door and a welcoming open porch area.

Home in Marvell

4.94 out of 5 average rating, 16 reviews

Tranquil home away from home

Relax with the whole family at this peaceful place to stay. The Parsonage accommodates everyone! 3 bedroom, 2 bath home in the center of town immersing you in a little slice of home. The house has two separate living areas, an eat-in bar, dining room and a fenced in backyard and storage building available if needed during your visit or hunting trips.

Guest favorite

A light blue bungalow with multiple sections is set among lush greenery. The home features a raised porch with steps leading up and a railing that enhances accessibility. Tall trees provide shade to the surrounding grassy area.

Home in Lyon

4.94 out of 5 average rating, 18 reviews

Guitar Frenchie’s Corner!

Take it easy in the heart of the Delta! This bungalow/ shotgun house is the perfect getaway for Blues lovers who want all the fun that Clarksdale’s home of the Blues has to offer and the quaint and quiet of old town Lyon, birthplace of Son House! Located 5min from the heart of Downtown Clarksdale MS. Come see us & hear great Live music!