
House vacation rentals in Port St. Lucie
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Top-rated house rentals in Port St. Lucie
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Port St. Lucie house rentals
House rentals with a pool

Splash Oasis: Retreat w/ Heated Pool, BBQ, FirePit

Lanai on the Links

Golf side view home with pool near beach

Castle Santa Clara

15mins from Beach|Cozy Coastal 3BR w/Pool Paradise

SE Florida - Heated Pool Home 12 min from beach

Tranquil | Pool | King Bed | Pet Friendly | WiFi

Relaxing Retreat in Lush Tropical Garden w/ Pool
Weekly house rentals

Dockside Luxury Waterfront Home

Massage chair, Firepit, Ping Pong, Huge Backyard

The Amazin' Abode

Relaxing Port St. Lucie Getaway with Lake Access

Beautiful home, relax and enjoy outdoor area !

Seaside Retreat | Walk to Coastal Eats & Activity

Adorable Stay

Welcome to Sunny Escape
Private house rentals

Life By The Sea -Outdoor pool, arcade, pool table

2BR Family Oasis – Pool • Arcade • Outdoor TV!

Treasure Coast Gem - Golf, Beach, Fishing, Pets OK

Home Resort Oasis One of One!

Backyard Oasis

Family Oasis in Port St. Lucie w/ Screened Pool

Playful 3BR Escape | Games, Arcades & Cozy Patio

Beautiful Private House
Quick stats about house rentals in Port St. Lucie
Total rentals
800 properties
Total number of reviews
19K reviews
Family-friendly rentals
550 properties are a good fit for families
Pet-friendly rentals
300 properties allow pets
Rentals with a pool
370 properties have a pool
Rentals with dedicated workspaces
450 properties have a dedicated workspace
Destinations to explore
- Seminole Vacation rentals
- Central Florida Vacation rentals
- Miami Vacation rentals
- Saint Johns River Vacation rentals
- Orlando Vacation rentals
- Gold Coast Vacation rentals
- Miami Beach Vacation rentals
- Fort Lauderdale Vacation rentals
- Tampa Vacation rentals
- Kissimmee Vacation rentals
- Four Corners Vacation rentals
- Key West Vacation rentals
- Rentals with a hot tub Port St. Lucie
- Villa rentals Port St. Lucie
- Rentals with a patio Port St. Lucie
- Pet-friendly rentals Port St. Lucie
- Rentals with beach access Port St. Lucie
- Rentals with pools Port St. Lucie
- Beach house rentals Port St. Lucie
- Family-friendly rentals Port St. Lucie
- Rentals with a fire pit Port St. Lucie
- Smoking-friendly rentals Port St. Lucie
- Waterfront rentals Port St. Lucie
- Fitness-friendly rentals Port St. Lucie
- Cottage rentals Port St. Lucie
- Beachfront rentals Port St. Lucie
- Rentals with outdoor seating Port St. Lucie
- Guesthouse rentals Port St. Lucie
- Rentals with a fireplace Port St. Lucie
- Apartment rentals Port St. Lucie
- Condo rentals Port St. Lucie
- Rentals with a kayak Port St. Lucie
- Rentals with lake access Port St. Lucie
- Rentals with a washer and dryer Port St. Lucie
- House rentals St. Lucie County
- House rentals Florida
- House rentals United States
- Stuart Beach
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- Rapids Water Park
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- Jonathan Dickinson State Park
- Golf Club of Jupiter
- Rosemary Square
- West Palm Beach Golf Course
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- Sebastian Inlet State Park
- John D. MacArthur Beach State Park
- South Beach Park
- Blue Heron Beach
- The Bear’s Club
- Jupiter Hills Club
- Jupiter Off-Leash Dog Beach
- Bear Lakes Country Club
- Norton Museum of Art
- John's Island Club
- Banyan Cay Resort & Golf
- Loggerhead Marinelife Center
- Jonathan's Landing Golf Club
- Medalist Golf Club
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