Vacation rentals in Pine Island

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Top-rated vacation rentals in Pine Island

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A garden-level apartment is accessed via a gravel driveway that leads to a charming home. Lush greenery surrounds the path, and the structure features a mix of siding colors, with large windows framed by blue shutters, creating an inviting exterior appearance.
Apartment in Rochester
4.93 out of 5 average rating, 208 reviews

Woodland Retreat, Full private walkout lower level

Peaceful retreat down gravel driveway 15 min from Mayo Clinic. Enjoy your own apartment with private backyard walkout entrance to the lower level of our home. You will have a bedroom, living area, kitchenette with mini fridge, microwave and toaster oven (no conventional stove/oven), bathroom w/ tub & shower, pingpong table, laundry, and patio with fire ring. You may hear piano music weekday afternoons, since I give lessons (usually 3-6 pm; a bit earlier in summer) NEW HEATED FLOORS w/thermostat

Top guest favorite
A welcoming living room features a plush brown sofa adorned with decorative pillows, complemented by a wooden coffee table. Natural light pours through the large window, illuminating the space. A potted plant and two stylish lamps add character to the cozy environment.
Home in Rochester
5 out of 5 average rating, 71 reviews

New! MN Comforts The Heart 4Bd/2Bth, 12min to Mayo

Welcome to MN Comforts The Heart! Are you here for work or leisure, or want to feel comforted after a Mayo appts? 12 min to Mayo Clinic, Wifi, work-station, ROKU/Smart TVs, and a fireplace in the family room. We offer a 2nd home feel. Near stores. Split-level, chill, and quiet, thoughtfully designed to cater to your needs, ensuring a comfortable, enjoyable stay. A blend of traditional & modern styling in a tranquil home, with fun opportunities for family & friends. Partially fenced backyard.

Top guest favorite
A serene view of a well-maintained lawn leading to a calm lake, framed by trees. A stone-edged garden bed with varied foliage is visible in the foreground. The water glistens under sunlight, and a dock is seen in the distance, enhancing the peaceful lakeside setting.
Home in Zumbro Falls
4.97 out of 5 average rating, 32 reviews

Zumbro Lake Home

Relax with the whole family, plan an ice fishing trip with your buddies, or enjoy the lake between clinic appointments. Large lawn with 160ft lake front perfect for swimming, kayaking, fishing, or just relaxing by the water. Full kitchen, laundry, 2 full bathrooms, 2 bedrooms, 2 queen beds and twin bunkbeds in the main house. A second, separate building referred to as the "Bunkhouse" features 3 double beds upstairs and a 2 double beds in the lower level. Within 20 minutes of the Mayo Clinic.

Top guest favorite
The exterior of a spacious home is shown, surrounded by well-maintained green lawns and shrubs. A paved driveway leads to the front of the house, with trees providing natural shade. The structure features a traditional design with appealing landscaping in a quiet setting.
Guest suite in Faribault
4.96 out of 5 average rating, 381 reviews

Sherry's Suite

Our beautiful suite of private rooms will accommodate up to 4 people. You can expect a very private, peaceful and comfortable atmosphere. A place that you can call 'Home' while being away from yours. During this time, with the Coronavirus and the need for social distancing, Lisa & I would like to assure you that the Suite is completely yours and there is no shared space within the home. We take extra care in making sure you are in a safe, clean environment. Have safe travel's and stay healthy.

Top guest favorite
Apartment in Rochester
5 out of 5 average rating, 5 reviews

The Travelers Flat, a walk to St. Mary’s

Situated in the historic and quaint neighborhoods surrounding St. Mary’s Hospital, this centrally-located home has just been fully updated for you! Fully furnished, this home is located on the top floor, and features a spacious living room, an adorable bedroom, bathroom, kitchen, which also includes a workspace, and a patio! Enjoy abundant natural light in this home that has windows facing south and west! Host is readily available and has over 5 yrs of experience serving Airbnb on lower level.

Top guest favorite
A spacious living area features warm wood beam ceilings and large windows, allowing natural light to fill the room. Modern furniture, including a comfortable white sofa and a glass dining table, is arranged to create an inviting space. Double doors lead to a backyard patio.
Home in Rochester
4.95 out of 5 average rating, 254 reviews

Euro House, Bright! Near Mayo-Single Family Home

Welcome to your home away from home! This private, single-family home was thoughtfully designed and is located in a quiet area just 5 minutes (0.9 miles) from the Mayo Clinic. Step into a master gardener’s dream—a beautifully landscaped yard filled with native plants and outdoor seating, perfect for relaxing after a long day. 2 Queen Bedrooms, 2 Full Bathrooms, modern finishes throughout, Super clean and pet-free. Off-street parking, Washer & dryer, Wi-Fi, Smart TVs & Fully stocked kitchen.

Top guest favorite
A welcoming book titled 'Welcome to Oasis' is displayed prominently, featuring a lotus flower design and neatly placed beside a decorative white vase. Greenery is visible in the background, adding a touch of nature to the inviting setting.
Home in Rochester
4.94 out of 5 average rating, 121 reviews

Oasis - Comfort & Serenity (Full house near Mayo)

*Discount for extended stays* Seeking a peaceful respite near Mayo Clinic in Rochester, MN? Look no further than "Oasis"–your ultimate home away from home. We offer 5 beds, 2 baths, & can accommodate up to 8 guests. Recharge in the workout & yoga meditation room, stay connected in the office area, & explore Rochester's attractions. Your dedicated host Peggy, a Mayo employee, will ensure a seamless/enjoyable stay. Book now & experience the perfect blend of comfort & serenity at Oasis.

Top guest favorite
A cozy living room space features a beige couch adorned with decorative pillows and a low coffee table. The white brick wall serves as a backdrop for a fireplace, which is framed by a wooden mantle decorated with artwork and a wreath. Natural light enters through a window.
Apartment in Rochester
4.97 out of 5 average rating, 258 reviews

Restful sanctuary close to Mayo Clinic

This cozy space has private, self-entrance with off-street parking at no cost...a mere 2.5 miles or 10 minute drive to the Mayo Clinic downtown. Located in a quiet neighborhood in northwest Rochester. Easy access to highways, grocery store, coffee shop, Target, restaurants and biking/walking trail. Completely furnished with linens, hair-dryer, Netflix and Hulu, Smart TV and Wi-fi....and a Keurig Coffee maker with enough coffee pods to get you started. Truly, a home away from home!

Guest favorite
The exterior of a charming blue building is presented, featuring large glass windows and a welcoming entrance. Flanking the doorway are two outdoor chairs, while flower planters add a touch of greenery. An American flag is displayed above, contributing to a friendly atmosphere.
Apartment in Hammond
4.86 out of 5 average rating, 35 reviews

Zumbro Valley Getaway

Enjoy your stay at our bright two-bedroom+ apartment! Located in the beautiful Zumbro River Valley, you are near the Zumbo River, popular for kayaking, tubing and fishing, and many scenic roads for biking and cruising. Rochester is 30 minutes away as is the Mississippi River and its river towns. A long, but gentle boardwalk takes you up to this apartment. Wonderful location to spend time with family and friends, or to getaway and enjoy the beauty of the driftless region.

Top guest favorite
The exterior of a cottage features a combination of dark wood and stone cladding, complemented by a black metal roof. A welcoming entrance showcases a wooden door with an intricate sun design and surrounded by greenery, providing a charming and inviting first impression.
Tiny home in Rochester
4.97 out of 5 average rating, 67 reviews

Luxury Cottage | 5 Blocks from Mayo | No Stairs!

Welcome to our Downtown Cottages, Rochester’s First "Tiny Homes" : 3 min drive/10-15 min walk to the Mayo Clinic Campus. Experience our four charming cottages- Enjoy zero-entry, slab-on-grade living with NO stairs, accommodating up to 4 guests. Elegantly furnished and fully stocked, each unit also includes off-street parking. Located just 5 blocks from the downtown Mayo Clinic Campus, our cottages offer the perfect blend of comfort and convenience. Book your stay today!

Guest favorite
A welcoming retreat house is showcased, featuring a wood-paneled exterior with a gently sloped roof. The entrance is framed by neatly landscaped greenery and a vibrant lawn, complemented by an American flag proudly displayed by the front door.
Home in Oronoco
5 out of 5 average rating, 26 reviews

Scrapbooking/Vacation retreat house on the water, country living, 15 min to Mayo Clinic Rochester, huge yard and so peaceful!!

Fully furnished retreat house set up to accommodate 9 guests (for winter scrapbooking/crafting/quilting retreats) as well as families or small groups looking for a great getaway home! The house is fully furnished with a main floor master bedroom and bath. Each room is set up with a large bed and set of bunks to accommodate any group. The home has a total of 9 beds (2 queens, 3 fulls and 4 twin) allowing ample space for multiple families and large groups!

Guest favorite
A modern kitchen is displayed, featuring white cabinetry contrasted against a deep blue wall. A stainless steel oven and a retro-style microwave are present on the countertop, alongside a coffee maker and kitchen utensils. Natural light enters through the window above the sink.
Home in Rochester
4.83 out of 5 average rating, 550 reviews

Cozy home next to Mayo Clinic & historic parks!

Cozy single level 2 bedroom, 1 bath. Fully furnished kitchen with TV, WiFi, and smart lock. It’s a 1.6 miles to Mayo Clinic. Walking distance to Historic Quarry Hill Park and Silver Lake Park. City bus line to Mayo Clinic 1/2 block away. Newly remodeled bathroom with full linen and toiletries. Quiet neighborhood, with full driveway parking. We also have a baby gate for the stairs. Enjoy your next home away from home !

Popular amenities for Pine Island vacation rentals

  1. Airbnb
  2. United States
  3. Minnesota
  4. Goodhue County
  5. Pine Island