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Vacation rentals in Mesquite

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Mesquite

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guesthouse in Las Cruces
Cozy Casita w/private patio near Old Mesilla
This adorable casita is located just one mile from Historic Mesilla and 2~ miles from NMSU. This one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/toaster oven/Keurig machine/double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), AC unit, electric heater, and a private outdoor patio table and gas grill. Onsite owners as casita is adjacent to our main home.
$68 per night
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Rental unit in La Mesa
Desert Sage Suite Off Hwy 28 - Walk to Chope's
Built in 1848, this updated adobe suite with southwestern boho vibes has all the modern amenities while embracing the small town feel. Sip morning keurig coffee on the patio or walk 1 block to the Mercantile for a cup of joe and pastry. Embrace the rural location at night with a great view of the stars. Located near wineries, breweries, flower farms, and classic Mexican fare. Great for those passing through, locals looking for a staycation, or the chill traveler embracing the journey.
$79 per night
Guesthouse in La Mesa
Little House in the Desert
Our guesthouse is located on historic Highway 28, also known as the Don Juan de Onate Trail, which connects El Paso and Las Cruces. It is one of the area's most scenic routes. You can find breweries, multiple wineries, and the famous Chopes restaurant and bar along the route. The highlight of the 10-mile drive from our little house in San Miguel to historic Mesilla takes you through unique canopies of pecan trees, in the largest pecan-producing county in the nation.
$79 per night
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Other great vacation rentals in Mesquite

Rental unit in Las Cruces
Chestnut Cottage Apt E
$55 per night
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Private room in Las Cruces
Master Bedroom with Full Bath & Kitchen
$47 per night
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Rental unit in Las Cruces
Solano Shay
$95 per night
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Private room in Las Cruces
Mi Casa Su Casa-Charming Cozy & private w patio
$58 per night
Home in Las Cruces
The Alamo on Ocotillo
$181 per night
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Home in Las Cruces
Rubivista Casita
$88 per night
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Home in Las Cruces
Pet Friendly Luxury Oasis With Pool and Hot-tub!EV
$193 per night
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Home in Las Cruces
Charming desert oasis with pool!
$132 per night
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Home in Las Cruces
Pet Friendly Luxury Retreat W/ Heated Pool & Spa
$197 per night
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Guest suite in Las Cruces
Welcome to Casita Escondida in Mesilla, NM!
$77 per night
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Home in Las Cruces
Spacious and clean 4-BR home with pool & hot tub
$220 per night
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Rental unit in Las Cruces
Casa Airbnb- Entire Apartment
$52 per night
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Other types of stays on Airbnb

  1. Airbnb
  2. United States
  3. New Mexico
  4. Doña Ana County
  5. Mesquite