Vacation rentals in Chesapeake and Ohio Canal

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Chesapeake and Ohio Canal

Guests agree: these stays are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

Apartment in Bethesda

4.82 out of 5 average rating, 148 reviews

European-style Apartment Near NIH

Small, modern, and perfectly functional European-style apartment with private entrance in a nice, quiet and cozy neighborhood in Bethesda, MD. Our place is close to Navy Hospital, NIH and Walter Reed Hospital, all connected via public transportation. The Metro station is within 1 mile, as well as groceries and shops. Ideal for solo or business travelers, this independent apartment has everything you need. But most importantly, this petite apartment has character, oh, and we're nice folks too :-)

Guest favorite

Guest suite in Bethesda

4.88 out of 5 average rating, 284 reviews

Spacious 1 bed with leafy patio, near NIH & metro

Our spacious, surprisingly bright Bethesda half-basement is nestled in a quiet neighborhood only minutes from Walter Reed, NIH, & the metro. Large windows offer a view onto a patio bordered with hydrangeas & evergreens; the bedroom has a queen-sized bed, a Samsung smart TV, & a desk. The Kohler shower head in the bathroom offers firm pressure and the mini-fridge & microwave are on hand for snacks. Short term rental license no. STR25-00162. Please note: There is no kitchen and no washer/dryer.

Top guest favorite

Guest suite in Bethesda

5 out of 5 average rating, 24 reviews

Spacious Apartment in Bethesda

Welcome to your private retreat in Bethesda with convenient access to DC! Our meticulously designed 1,500 sq ft, 2-bedroom, 2-bath, completely independent apartment offers a perfect blend of modern elegance and homey comfort, ensuring an unforgettable stay. Located on the lower walkout level of our custom-built private home, this upscale unit is thoughtfully designed with your privacy in mind featuring its own separate entrance. Montgomery County Short-Term Residential License STR24-00027.

Guest favorite

Home in Bethesda

4.95 out of 5 average rating, 165 reviews

Luxury basement apt all private with private entry

Indulge in modern luxury with this 1B 1 SPA like bathroom apartment. This elegant apartment is meticulously designed to offer a harmonious blend of comfort and opulence. This bedroom provides a tranquil oasis, ensuring that your stay is a pleasure. The kitchen is fully stocked. With a dedicated laundry room and coffee/Tea bar. Experience a sophisticated haven with unparalleled location, only over a mile away from Downtown Bethesda, 2 blocks from NIH, All major highways only 5min drive.

Top guest favorite

Home in Bethesda

4.98 out of 5 average rating, 207 reviews

Stylish Spacious Greentree Apartment

This 1,500 sq ft spacious luxury apartment is located in the lower level of a private custom home. NO SHARED HVAC. Sunny and light bedrooms with top-notch finishes and décor. Private entrance and walkway, covered porch, and free on-site parking for 2 cars. Prime Bethesda location: 1 mile to NIH and Naval Medical with public transportation just outside the front door. Bus 47 (free to ride) takes 10 minutes to Bethesda Metro station (Red-line) or in the opposite direction to Montgomery Mall.

Guest favorite

Apartment in Glen Echo

5 out of 5 average rating, 12 reviews

Charming, comfortable, unique 2 bedroom apartment

Welcome to 3 Vassar Circle, a 2 bedroom apartment in the Washington Metro area, centrally located near all major airports .The beautifully decorated unit is housed within a stone colonial home in historic Glen Echo. The unit features a large sunlit living / dining room with an up to date kitchen, a washer and dryer, two comfortable bedrooms with first class linens , a screened porch and patio with grill. Whether traveling for business or tourism, 3 Vassar will be your home away from home

Top guest favorite

Home in Falls Church

4.99 out of 5 average rating, 119 reviews

Charming 2BR 2BA Suite-Close to DC

Lovely basement suite in a luxury single-family home with a private entrance through the backyard. Enjoy complete privacy with a locked door separating it from the main floor. Great location! About a 20-minute walk to West Falls Church Metro, with $3/day parking (free on weekends and federal holidays). A convenient option for sightseeing in DC. About 10 miles from the White House and close to restaurants, Tysons Corner mall, and grocery stores like Giant, Whole Foods, and Trader Joe’s.

Top guest favorite

Home in Washington

4.96 out of 5 average rating, 244 reviews

The White House Luxury Bunker

Enjoy your Washington experience in our charming, comfy, neat basement apartment with private entrance in Chevy Chase, DC, Historic District. A very cozy place to relax before and after you explore all the wonderful things that DC has to offer! A luxury one-bedroom, full bathroom (shower), living room, kitchen and laundry in a distinct early 20th Century home. Great cafes, restaurants, and bars are within walking distance. Easy access to the Metro (Red Line) Friendship Heights.

Top guest favorite

Apartment in Bethesda

5 out of 5 average rating, 117 reviews

Private Suite - NIH, Metro

New, fully-equipped studio apartment with private entrance. Access our apartment with a keyless check-in and enjoy the queen-sized bed, futon, kitchen, workspace, and full bath with washer and drier included! Electric car charging is available, as well as parking on premises. 10-minute walk away from the red-line metro! Located across the street from NIH and less than a mile from downtown Bethesda, where you can find restaurants, bars, Trader Joes, CVS and Target.

Top guest favorite

Home in McLean

5 out of 5 average rating, 36 reviews

Modern Luxury in the Heart of McLean

Welcome to this newly constructed modern masterpiece in the heart of McLean. Thoughtfully planned with curated designer furnishings, finishes, and statement lighting, this residence offers a truly elevated living experience. Ideal for families, executives, and discerning travelers, the home offers refined comfort for up to 8 adults plus 1–2 small children. To reserve your stay, please submit an inquiry and share a bit about yourself and your party.

Guest favorite

Home in Rockville

4.93 out of 5 average rating, 153 reviews

Spacious Family-Friendly Basement w/ Coffee Bar

Cozy, private basement ideal for families, business trips, or quiet getaways. Includes queen bed, 68" sofa bed, private bath, family room with dining area, coffee bar, and smart TV in both the family room and bedroom. Enjoy fast Wi-Fi, shared washer/dryer, private side entrance, and driveway parking. 20-min walk to Metro, near shops, dining, and parks. Quiet Rockville neighborhood with easy DC access. Guests love the space, comfort, and convenience!

Guest favorite

Apartment in Bethesda

4.96 out of 5 average rating, 114 reviews

Perfect Bethesda Apartment for NIH and Walter Reed

Comfortable 550 SF 1-BR 1-BA lower level apartment in single-family neighborhood; bright open floor plan; private front entrance; WiFi; eat-in kitchen, Queen bed, chaise/sofa converts to Queen sleeper; and, short walking distance to major grocery chains and restaurants. It’s home away from home! Plus, the added peace of mind with the confidence in a full house generator to ensure that you are always safe, secure and connected!