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Family-friendly vacation rentals in Cayce

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Cayce

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite
A dining area is presented with a round table surrounded by four wooden chairs. A delicate chandelier provides overhead lighting, while a window with sheer curtains allows natural light to enter. A soft-colored wall enhances the serene space, complemented by a wall art piece.
Home in West Columbia
4.93 out of 5 average rating, 284 reviews

Lucy’s Place

This 950 sq ft minimalist home is the perfect place to relax with family and friends. This West Columbia home is in a convenient spot for you to spread out and make yourself at home. The home is only 2 miles off of the interstate if you are just traveling through. You’ll be about 10 minutes from the University of South Carolina, Colonial Life Arena, the Statehouse, Riverbanks Zoo, Williams Brice Stadium, the Vista, The Columbia Riverwalk and many more local attractions if you are staying a while

Top guest favorite
The exterior of the duplex is shown, featuring a well-maintained lawn with fallen leaves and a pathway leading to the entrance. Large windows are visible, allowing natural light, while an American flag adorns the front. A mailbox marked '116' is positioned at the driveway.
Guest suite in Columbia
4.93 out of 5 average rating, 378 reviews

Comfy & Private Left Half of a Duplex

Lexington Permit #2500623 Listing is a private, cozy half duplex. Private entrance, parking in a quiet neighborhood. Bathroom has a new large shower, towels, shampoo/conditioner, lotion, soap, vanity. Bedroom has queen bed, walk-in closet, TV. Kitchenette has sofa lounger, microwave, mini fridge, TV, coffee makers (single cup/round pod or ground type), dishes, glasses, silverware. *1 mile from Saluda Shoals Park/ Lake Murray. *4 miles from Columbian Mall - tons of shopping and restaurants.

Top guest favorite
A well-arranged bedroom features a spacious bed dressed in white linens and a grey throw blanket. Two reading lamps are positioned on either side of the headboard. Carpeting covers the floor, and natural light filters through a window dressed with white curtains.
Apartment in Columbia
4.96 out of 5 average rating, 108 reviews

Heathwood 2Br/1Bath Cozy Home

Close to everything when you stay at this centrally located duplex. Close to the grocery store and restaurants. Five Points (1.5 miles), the Vista (2.5 miles), Township Auditorium (2 miles), USC (2 miles), and Ft Jackson (3 miles). This freshly renovated unit includes 2 bedrooms, 1 bath, fully equipped kitchen (including a k-cup coffee maker), washer and dryer. Both bedrooms have memory foam beds (1 King & 1 Queen). Keyless entry. Off street parking for 2 cars. COC Permit STRN-001336-10-2026

Guest favorite
A comfortable living space features a black leather sofa draped with a soft throw blanket. A round black coffee table with gold accents is positioned in front of the seating. A tan armchair completes the arrangement, set against soft beige carpet and light gray walls.
Home in Cayce
4.9 out of 5 average rating, 208 reviews

Columbia’s Best Airbnb

Take it easy at this unique and tranquil getaway. Our Airbnbs are the nicest in each town. From our known luxurious mattresses to the best kept secret… 3D luxury digital Massage chairs relax you from any stressful situation. See why we are ambassador Airbnb host. Stay at this location and you are 5 to 10 minutes to the USC baseball, basketball and Football. Campus is same. Airport is 4 miles. Great kid activity at EdAdventure kid museum. I 26, I-77 and downtown Columbia are minutes away.

Guest favorite
A charming outdoor space is surrounded by lush greenery, featuring a table with chairs and a wooden bench. The cottage is visible with vibrant yellow doors, while the nearby building provides additional context. Colorful flowers are arranged in pots throughout the garden.
Guesthouse in Elmwood Park
4.89 out of 5 average rating, 975 reviews

Lizzi & Scott’sTiny Guest House secluded USC-Vista

Welcome to our tiny guest cottage hidden in the heart of the city. It's within blocks of restaurants, coffee shops, an art movie house, and a lovely river walk. The Lace House/Governor’s Mansion, business district, MiLB & UofSC are a short walk or bike ride away. At the rear of our home, it’s private, secure & quiet. A partition & movable screen separate the bathroom area. There’s a smart tv, small fridge, microwave, coffeemaker & work-table.24 hr self check-in. STRO-000579-03-2024

Top guest favorite
A modern kitchen with sleek white cabinetry and granite countertops is highlighted. Four black bar stools are positioned at an island, and stainless steel appliances, including a stove and refrigerator, are visible. Natural light enters through multiple windows, creating a bright and functional space.
Home in West Columbia
5 out of 5 average rating, 102 reviews

Golden Reflections Getaway

Welcome to the Golden Reflection Getaway—a spacious, stylish retreat perfect for families and groups. Enjoy this 2,600+ sq. ft. spacious family area with three luxury themed bedrooms upstairs and extra sleeping options with a full bathroom on the main level. Tucked away in a peaceful neighborhood, just 7 minutes from the vibrant heart of Downtown Columbia and 18 minutes from Fort Jackson. Relax, recharge, and make lasting memories in this thoughtfully designed and comfortable home.

Guest favorite
A charming tiny home is surrounded by trees and features a welcoming front porch with wooden decking. An outdoor fire pit, with several Adirondack chairs arranged around it, creates a cozy gathering space. Warm light emanates from the windows, highlighting its cozy atmosphere.
Tiny home in West Columbia
4.97 out of 5 average rating, 107 reviews

Lux Tinyhome near DT/USC/Ft. J.

This is one of a kind tiny but mighty home. At just around 300sq ft, it packs all most popular essentials including washer & dryer, cooking area, & more. Completely private (fenced throughout), located besides our popular pre-war farmhouse. Built around trees, this home will feel cozy and peaceful. Great for couples or very small families interested in glamping type experience. Its large window will bring in lots of light and drapes will black-out space when desired.

Guest favorite
The exterior of a detached studio apartment is shown, featuring a light-colored façade and a charming blue door. Two large windows provide natural light, while a shaded carport is visible on the left. Lush greenery surrounds the entrance, contributing to a serene environment.
Guesthouse in Cayce
4.89 out of 5 average rating, 154 reviews

The Avenues Bungalow

This space is great for a solo traveler or a couple! Great location, quiet neighborhood, close to everything. Mile and a half from USC campus (Carolina Baseball stadium, Colonial Life Arena and State house). Five miles from airport. Three miles from Williams-Brice Stadium. Three Miles from 5 points. Music venues, restaurants and riverwalk around the corner! Please note: This is a studio apartment in the back of a single family home. Private driveway, entrance and space.

Top guest favorite
A cozy dining area features a round wooden table surrounded by a mix of modern and rustic seating. Natural light is welcomed through nearby windows, and warm lighting is provided by hanging pendant fixtures. A decorative storage unit displays various items, adding character to the space.
Home in Cayce
4.96 out of 5 average rating, 161 reviews

High-styled Historic - (UofSC)

Built in 1959, this home has been completely remodeled with modern luxuries, and original hardwood floors throughout still tell the tales of decades of love and history. The decor gives a nod to a New York City loft style space, with a blend of both clean modern lines and warm rustic finishes. 1.2 mi - Steel Hands Brewing 1.8 mi - University of South Carolina 2.2 mi - Riverbanks Zoo & Garden 3.6 mi - Williams Brice Stadium 4.9 mi - Columbia Metropolitan Airport

Top guest favorite
The outdoor deck is highlighted with warm string lights providing soft illumination. Comfortable seating options, including a couch and a bench, are arranged thoughtfully, with a decorative rug beneath. The entrance features a door, inviting guests into the cozy camper space beyond.
Camper/RV in Lexington
4.99 out of 5 average rating, 109 reviews

The Hideaway

Renovated stationary camper nestled in its own private space on 12 acres. This is around 200 square feet indoor living area but over 300 square feet outdoor space for your enjoyment. Secure 5 ft. Fence for your fur babies to be safe in. There are 2 other Airbnbs on this property with ample distance between the houses. Residental toliet with septic tank .Tankless hot water heater with endless hot water. Washer/dryer/dishwasher in its own space behind camper.

Guest favorite
A bright living area features a soft color palette with a cozy rug underfoot. A pair of comfortable sofas are positioned around a wooden coffee table. Light from windows illuminates the space, enhancing the welcoming atmosphere, and an open archway leads to the dining area.
Home in Cayce
4.96 out of 5 average rating, 105 reviews

In Columbia Metro! Easy drive to Fort Jackson/USC

Metro Columbia. 1.5 miles to USC. 9 miles to Fort Jackson! Entire single family home. Two bedrooms. One has a KING bed and the other has a QUEEN bed. One bath. Additional rollaway bed in an enclosed sunroom. Includes linens, sofa, loveseat, refrigerator, dishwasher, garbage disposal, wash machine, dryer, outdoor covered patio with rocking chairs and dining table overlooking the huge fenced, private backyard. Bright, comfortable, quiet. Plenty of parking.

Guest favorite
A charming brick exterior features a welcoming entrance with steps leading to a covered porch adorned with plants. Large windows allow natural light to brighten the interior. Surrounding greenery provides a tranquil setting in a peaceful residential neighborhood.
Apartment in Earlewood
4.93 out of 5 average rating, 310 reviews

The Toad Abode Studio

Relax and unwind in this cozy, centrally located studio. Perfect for travelers, the space features a comfortable double bed, work desk, cozy reading chair, and TV for your downtime. The kitchenette area includes a microwave & mini fridge with ample coffee & tea supplies, while the bright bathroom offers plenty of natural light. All the essentials you need for a comfortable stay. **Checkout on a Monday for more options at a discounted Sunday rate.

Popular amenities for Cayce family-friendly rentals

Quick stats about vacation rentals that are family-friendly in Cayce

  • Total vacation rentals

    Explore 240 vacation rentals in Cayce

  • Nightly prices starting at

    Cayce vacation rentals start at $40 per night before taxes and fees

  • Verified guest reviews

    Over 14,690 verified reviews to help you choose

  • Pet-friendly vacation rentals

    Find 100 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    150 properties have a dedicated workspace

  • Wi-Fi availability

    240 of Cayce vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Cayce rentals

  • 4.8 Average rating

    Cayce stays are highly rated by guests—averaging 4.8 out of 5!

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