
Vacation rentals in Santa Isabel
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Top-rated vacation rentals in Santa Isabel
Guests agree: these stays are highly rated for location, cleanliness, and more.
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Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santa Isabel vacation rentals
Other great vacation rentals in Santa Isabel
Guest favorite

Home in Salinas
4.92 out of 5 average rating, 223 reviewsBeautiful House w private Pool
Guest favorite

Apartment in Ponce
4.91 out of 5 average rating, 91 reviewsYisley’s House
Guest favorite

Home in Santa Isabel
5 out of 5 average rating, 5 reviewsPretty house
Top guest favorite

Home in Coamo
4.98 out of 5 average rating, 46 reviewsMiah House/Pool/Solar Energy/Water Reserve
Top guest favorite

Tiny home in Hayales
4.98 out of 5 average rating, 49 reviewsVilla Aires del Campo
Top guest favorite

Home in Santa Isabel PR
5 out of 5 average rating, 13 reviewsLas Casitas Beach Retreat
Top guest favorite

Tiny home in Puerto Rico
4.97 out of 5 average rating, 70 reviewsCasa Verdor-Couples/Botanical Hot Tub
Top guest favorite

Cottage in Adjuntas
5 out of 5 average rating, 73 reviewsCasita Retreat River Pool Oasis
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- Playa del Dorado
- Playa Mar Chiquita
- Playa de Vega
- Distrito T-Mobile
- Playa de Tamarindo
- Playa Puerto Nuevo
- The Saint Regis Bahia Golf Course
- Peñón Brusi
- Toro Verde Adventure Park
- Coco Beach Golf Club
- Los Tubos Beach
- Playa Maunabo
- Playa de Cerro Gordo
- Beach Planes
- Balneario Condado
- Punta Guilarte Beach
- Playa Puerto Nuevo
- Cerro Gordo National Park
- Museo de Arte de Ponce
- Stream Thermal Bath
- Cueva del Indio
- Playa Las Palmas
- Playa de Jauca
- Museo de Arte de Puerto Rico
- Family travel hub Tips and inspiration
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- Outdoor adventure Explore nature with the family
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