Hotel vacation rentals in Santa Cruz de la Sierra

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Top-rated hotel rentals in Santa Cruz de la Sierra

Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.

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The exterior view captures a multi-level building featuring natural stone walls and large glass windows. A softly lit bedroom is visible, framed by a balcony adorned with greenery. The city skyline glimmers in the background, creating a relaxed night ambiance.

Hotel room in Centro

4.75 out of 5 average rating, 68 reviews

Luxurious 5 Star Hotel Suite in Equipetrol area

Located in the best neighborhood in the city, Barrio Equipetrol. You'll be staying in a 118m2 Suite at a 5-Star hotel where you can enjoy the safety and comfort of a top-rated hotel. Work trip? With a co-work space and blocks away from the Business Area of the city. Coming to explore Santa Cruz? Only steps away of San Martin Avenue to visit the most trendy restaurants, shopping malls and social experiences in Santa Cruz. Also located only 10 minutes away from the historical center of the city

Top guest favorite

A charming outdoor space is presented, featuring a stone pathway bordered by greenery and potted plants. Lush palm trees and vibrant flowers add to the landscaping. The two-story structure stands in the background, providing a glimpse of a inviting entrance and balcony.

Private room in Santa Cruz de la Sierra

5 out of 5 average rating, 6 reviews

Private room

Disfruta de una habitación privada y confortable en una ubicación estratégica y segura a solo media cuadra de una avenida principal, a pasos de centros comerciales, supermercados, mercados y bancos, lo que te garantiza comodidad y fácil acceso a todo lo que necesitas. Contarás con cama queen de 2 plazas ideal si vienes con tu pareja, Smart TV, Wi fi, baño privado con calefón, una sala con un sofá cama, frigobar y una mesita para merendar. ¡Perfecta para pasar unos días en Santa Cruz!

Superhost

A well-furnished bedroom is presented with three beds featuring neutral-toned linens and textured bedcovers. A wall-mounted television is positioned above a wooden cabinet, while a door leads to a bathroom area. Warm lighting emphasizes the clean, bright environment.

Hotel room in Equipetrol

4.75 out of 5 average rating, 4 reviews

Furnished apartment for executives - Equipetrol

Apartment of 58mts, 1 bedroom, 1 bathroom, living /dining room, kitchen and terrace. 1 flat screen TV, cable TV with 100 channels, air conditioning heat/cold in all environments, digital safe, 2 wifi signals with fiber optic. It has an excellent location (100 meters from the Tajibos Hotel Convention Center, 200 meters from the Business Center and 400 meters from the Ventura Mall). In addition to a team for your attention 24 hours a day, during your visit.

A clean and modern bathroom entrance is framed by a wooden door. The space features a white toilet, a shower with a glass door, and a vanity with a large mirror. Soft lighting and neutral tiles enhance the bright and open atmosphere.

Hotel room in Centro

4.69 out of 5 average rating, 13 reviews

Centrally located private room, Downtown Santa Cruz

Imagine waking up every morning in a cozy LP® room, where we have brought the beauty of Santa Cruz inside the hotel with typical plants and trees that will immerse you in the nature of the region. Surrounded by greenery and freshness.🌿🏝️ In addition, our altarpiece, handmade by a talented Bolivian artist, embodies the majesty of the trees of Tajibos and Toborochis, adding even more charm to your experience. 🎨🌺

Guest favorite

A calming pathway leads to the entrance of a white exterior house, framed by green grass and small trees. A wooden door is visible, accompanied by a chair placed beside the entrance. Bright blue skies add to the serene atmosphere.

Private room in Valle Sánchez

4.85 out of 5 average rating, 66 reviews

A few minutes from the airport.

After an exhausting trip, nothing better than resting in a quiet and peaceful place while waiting for your next destination. If you are an animal and plant lover, you will feel especially loved, accompanied by nature and our pets if you wish. As the hammock sways, you can read a good book, listen to music, or enjoy a delicious grilled meat with vegetables and have some delicious juices with seasonal fruits.

Casa particular in Santa Cruz Department

House in a condominium Resort

LaCasa is located 7 minutes from Viru Viru International Airport on Kilometro 9 to the north. This family condominium will exceed your expectations by having a RESORT style. The house is designed for 5 people and an additional sofa bed for a sixth person if necessary, fully equipped, sauna pools, parks, sports courts, supermarket, all in one place, ideal for a vacation in a safe and family environment.

Top guest favorite

A black chair is positioned near a window, displaying three decorative cushions stacked in varying shades of gray and beige. Soft towels in cream and navy are neatly folded on the seat, adding a touch of comfort to the space.

Private room in Centro

5 out of 5 average rating, 18 reviews

Quiet and close to everything.

Enjoy this cozy, quiet and central stay, where you can rest comfortably, in addition to being a perfect base to explore the city since we are just a few minutes from the center, we also have shared spaces inside the house, where you can prepare your food and we will also include a delicious welcome breakfast from the second day of stay so you can enjoy the way it should be!

An outdoor seating area is presented under a covered patio, featuring a stone accent wall and comfortable sofas arranged around a low coffee table. Vibrant pink bougainvillea plants add a touch of color, while the grassy area offers a peaceful setting.

Casa particular in Santa Cruz de la Sierra

4.8 out of 5 average rating, 20 reviews

Very comfortable house with 3 bedrooms

Very comfortable house with three spacious bedrooms and 2 full baths, kitchenette, dining room, shared pools, shared pools, shared churrasqueras, green trails, large gardens, Polo courts, tennis, soccer and basketball and a beautiful natural lagoon. has free parking, WiFi, TV. Located 20 minutes from downtown very close to Viru Viru Airport

Vacation rentals for every style

Get the amount of space that is right for you

Apartments

Convenient locations with everyday essentials

Cottages

Quaint homes, peaceful surroundings

Houses

A space thats all yours, with room for everyone

Popular amenities for Santa Cruz de la Sierra hotel rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Family-friendly hotel rentals

Superhost

A spacious bedroom area is presented with a large double bed, complemented by a light-colored bedspread and matching pillows. A glass wall separates the kitchenette, with a round dining table and modern chairs visible in the foreground. A wall-mounted air conditioning unit is installed for comfort.

Hotel room in Equipetrol

4.73 out of 5 average rating, 15 reviews

Fully Equipped Studio - 2 people

FreddyRating, 5 stars64 months ago

Excellent service, always very friendly and ready to help. The place is very central, everything has everything first hand. 100% recommended.

A well-appointed sleeping area features a spacious bed dressed in white linens, complemented by decorative pillows. Nightstands with lamps provide soft lighting, while a colorful piece of wall art adds character to the room. Natural light filters in through a nearby window covered by golden curtains.

Hotel room in Warnes

Los Jazmines Private Room A

RudolfRating, 5 stars64 months ago

Located just outside of Warnes, the property is a green oasis, with a large garden, football field, pool, and also barbecue areas. Rooms are very clean and staff very friendly and helpful. After a trip through the partially dusty Bolivia, a great place to breathe. Mario speaks other perfect German.

Superhost

A modern kitchen area features a glass dining table with metal chairs. A stainless steel refrigerator stands beside wooden cabinetry, with kitchen utensils and appliances visible, including a gas stove. The space is well-lit with natural light from the open doorway leading to the living area.

Hotel room in Equipetrol

4.71 out of 5 average rating, 7 reviews

Comfortable, spacious and equipped apartment -Equipetrol

JuanRating, 5 stars95 months ago

We were very comfortable, the staff who attended us is excellent, highly committed to service, friendly , dedicated, always ready to help in everything, we sincerely recommend this alternative

Superhost

A bright dining area is highlighted by a glass table set with tableware, positioned near a large window that allows natural light to fill the space. A vibrant orange sofa is situated across the room, with a kitchen area visible in the background.

Hotel room in Equipetrol

4.83 out of 5 average rating, 6 reviews

Fully equipped family apartment - Equipetrol

DebRating, 5 stars77 months ago

Jorge's flat is very nice and clean. Jorge communicated very well. Jorge also arranged an airport shuttle to the flat. The check-in was very easy. There is a staff on-site available 24/7 to attend to any issues.

Superhost

A light-filled living area features a tan sofa bed and a glass dining table set with two chairs. Soft curtains frame the large window, while neutral walls enhance the spacious feel. A kitchenette is visible in the background, adding functionality to the space.

Hotel room in Equipetrol

5 out of 5 average rating, 5 reviews

Equipped apartment in equipetrol for 4 executives

AmancayaRating, 5 stars56 months ago

Jorge is the best host I met in Bolivia from afar Incredible attention, request airport pick up service and everything excellent! With biosafety measures and impeccable cleanliness. The 5 star price-servation ratio! Jorge is always attentive and willing to help, excellent! Options for improvement: Breakfast before 8:00 AM The best of the apartment: Location Note Cleaning Ease Host communication Would I be back? Yes, without hesitation!

Superhost

A bright and spacious living area is shown, featuring a glass dining table set for a meal. A comfortable orange sofa sits across from a contemporary shelving unit. Natural light filters in through a large window, complemented by soft curtains.

Hotel room in Equipetrol

4.33 out of 5 average rating, 3 reviews

Department - family full equipped Equipetrol

Jaime EduardoRating, 5 stars90 months ago

A place in the best area of Santa Cruz, with everything you need for a good day in this city. Close to great restaurants and shopping malls! Jorge and his team were always on the lookout for anything.

Superhost

A living area features a light-colored sofa bed positioned against a peach wall. A glass dining table is accompanied by metal chairs, and a small bowl with decorative items adds a touch of detail. Natural light streams through sheer curtains, enhancing the space's brightness.

Hotel room in Equipetrol

Fully equipped apartment for work teams

SusanaRating, 5 stars88 months ago

The apartment is very clean and comfortable! We had to use the sofa bed and they didn't hesitate to give us sheets and pillows! Excellent!

Superhost

A light-filled living area showcases a beige sofa bed positioned near a round glass dining table set for four. Soft peach walls complement modern decor, while large windows are dressed with neutral curtains, enhancing the inviting atmosphere of the space.

Hotel room in Equipetrol

4.89 out of 5 average rating, 9 reviews

Furnished apartment for executives in Equipetrol

JosephRating, 5 stars51 months ago

A really nice place to stay

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Hotel rentals with a pool

Hotel room in Centro

4.17 out of 5 average rating, 12 reviews

Feel like home !! Breakfast included !!

EricRating, 5 stars20 months ago

Excellent location to know the center of Santa Cruz, everything in order and the hosts are very friendly and helpful. I highly recommend them.

A vibrant sunset casts warm colors over the skyline, visible from a balcony. Lush greenery is framed by the balcony railing, while a swimming pool glimmers below, reflecting the evening light. The architectural details of nearby buildings provide a quaint contrast.

Hotel room in Equipetrol

4.67 out of 5 average rating, 3 reviews

5-star suite.

MoisesRating, 5 stars15 months ago

Wonderful place…!!!

A spacious hotel room features a large bed dressed in crisp white linens. A comfortable armchair is positioned beside a window with sheer curtains, allowing natural light to filter in. A wall-mounted television and a small desk complete the contemporary decor.

Hotel room in Colinas del Urubó

Suite Hotel Radisson

A spacious room features a comfortable bed centered under an ornate ceiling light. Wooden accents complement the decor, and a sitting area includes a small dining table beside glass doors leading to a balcony. A decorative mirror and a television are positioned against the wall.

Hotel room in Centro

Family Room in the Center

A bright bedroom features a spacious bed adorned with crisp white linens. The floor is decorated with rose petals, and red heart-shaped balloons are placed around the room. Elegant crown molding accents the ceiling, while natural light enters through a nearby window.

Hotel room in Centro

Love Escape Plan

A modern bedroom features a spacious bed with neutral bedding and decorative pillows. A mirrored wardrobe reflects the light and ample space. Natural light filters through sheer curtains, adding brightness to the room, while air conditioning is mounted above for comfort.

Hotel room in Santa Cruz de la Sierra

Ortiz Suites

A spacious bedroom features a king sized bed dressed in neutral linens, complemented by decorative pillows. A large window offers ample natural light, while a wall-mounted television and a dark wood dresser add functionality. A small seating area is set beside the window.

Hotel room in Warnes

Sun Hotel, Santa Cruz

A spacious bedroom features a large bed with white linens, complemented by two bedside lamps. A window with sheer curtains allows natural light to fill the room. A chair and small table are positioned near the window, and a television is mounted on the wall.

Hotel room in Santa Cruz de la Sierra

5-star Radisson Hotel, buffet breakfast included

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Hotel rentals with a patio

A spacious hotel room features a large bed adorned with crisp white linens. A desk and chair are positioned beside a large window, allowing natural light to brighten the space. Warm tones are present in the decor, complemented by soft lighting fixtures.

Hotel room in Colinas del Urubó

Luxurious Hotel Suite

SebastianRating, 5 stars2 months ago

Excellent communication , the room is very comfortable ! and clean

A modern bathroom is equipped with a spacious glass shower enclosure and a stone vanity. The sink features a sleek faucet, and a large mirror is mounted above the counter, enhancing the room's bright ambiance. Soft towels are neatly arranged nearby.

Hotel room in Centro

Hotel in the city center

WojtekRating, 5 stars2 months ago

The property was well adapted, large bathroom, TV, fridge. Everything you need. In addition, close to downtown

A modern bedroom features a spacious bed with crisp white linens. A flat-screen television is mounted on the wall opposite the bed. Soft lighting is provided by bedside lamps, and warm wooden flooring adds to the inviting ambiance.

Hotel room in Colinas del Urubó

Hotel in Santa Cruz - Bolivia

DanielRating, 5 stars9 months ago

Great place. 1st quality 100% recommended!!!

A bright guest room features a spacious bed covered with a colorful floral blanket. Two pillows are arranged at the head of the bed. Sheer curtains frame the window, allowing natural light to fill the room.

Private room in Santa Cruz de la Sierra

4.75 out of 5 average rating, 4 reviews

Guest Room in P.H.

Juan PabloRating, 5 stars5 months ago

The place is as described, the neighborhood is excellent, good business!

A spacious bed with a textured white blanket is centered against a wooden headboard. Nightstands on both sides hold elegant lamps, and a small decorative plant is positioned on one. A remote control sits on one nightstand, contributing to the cozy environment.

Hotel room in Santa Cruz de la Sierra

1-bedroom apartment with private bathroom

Monica NoeliaRating, 5 stars8 months ago

Good place ,,,, cozy

A well-lit room features a spacious bed adorned with an orange blanket and bright yellow pillows. A television is mounted on the wall opposite the bed. Large windows are dressed with light-colored curtains, and a small refrigerator is placed near a dark wooden nightstand.

Private room in Centro

4.33 out of 5 average rating, 15 reviews

Double bed room with balcony

FernandoRating, 5 stars11 months ago

It has to improve everything the construction is old was not worth it

A spacious sleeping area is highlighted by a wooden bed, dressed in a blue and white striped blanket. A bedside table holds a lamp, and natural light enters the room through curtains. A small plant adds a touch of greenery to the ambiance.

Private room in Santa Cruz de la Sierra

5 out of 5 average rating, 4 reviews

Beautiful suite 10 minutes from the airport

HarisRating, 5 stars34 months ago

Gustavo’s place is beyond amazing. The suite I stayed at was super spacious and had a very comfortable bed/pillow. Gustavo himself was an *excellent* host for accommodating me at 10:30pm with open arms after my overnight flight got postponed. In addition, the place is only a 15 minute drive to the airport which made going back the next morning super easy :)