Skip to content

Vacation rentals in Santa Cruz County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Cruz County

Guests agree: these stays are highly rated for location, cleanliness, and more.

Cottage in Patagonia
Historic Alma's Cottage in heart of Patagonia, Az.
Alma's is a private, artful and charming miner's cabin with a queen bed in the master and a twin in separate room and a complete kitchen. Sitting porch in front and back courtyard off the kitchen. Year around bird feeders keep our gardens busy with a rich variety of regional birds. Walk to shopping and restaurants. Audubon, Nature Conservancy and Borderlands are nearby. Alma's is one of our three Casitas Frontera, Gallery Frontera and La Frontera Realty.
$135 per night
Rental unit in Nogales
Las Hacienditas Large 2 Bedroom Apartment
Located in the beautiful town of Rio Rico. Just a few minutes from the Mexican border and from the art community at Tubac. A few blocks from a beautiful walking trail, gymnasium and several churches. This private apartment has all the amenities you need for a short or long stay. We take all the necessary steps to make sure the space is sanitary by disinfecting all areas and washing all bedding and linens to protect you and your family or guests.
$83 per night
Rental unit in Tubac
Private and Unique AirBnB in Tubac
Located in the historic district of the village; a Tubac icon. Private, secure, best location, warm weather, fast Internet, comfy bed, complete kitchen, high quality AC, quaint, free easy parking, washer/dryer, walled courtyard with a beautiful fountain, walk-in shower. Eight excellent restaurants within 1 mile. An exceptional value, best price, no deposit or cleaning fees. Totally sterilized after all guests.
$110 per night

Vacation rentals for every style

Get the amount of space that is right for you

  • Homes
  • Hotels
  • Unique stays

Other great vacation rentals in Santa Cruz County

Home in Sonoita
The Adobe House - Historic Wine Country Getaway
$152 per night
Guesthouse in Rio Rico
Cozy Rio Rico guesthouse with a view
$70 per night
Home in Rio Rico
All amenities Casita!
$79 per night
Guest suite in Patagonia
"The Studio" at Casa Hermosa
$85 per night
Home in Sonoita
Winemaker's Casita in the heart of Wine Country
$134 per night
Guesthouse in Tubac
Quilt Room (Inexpensive Birders Mecca)
$105 per night
Condo in Tubac
Welcome to your Southwest Paradise! New townhouse
$117 per night
Guest suite in Tubac
Private Tubac Retreat under The Milky Way
$75 per night
Townhouse in Tubac
Hike, Swim, Work from our Desert Home
$91 per night
Home in Patagonia
Charming historic house in downtown Patagonia
$140 per night
Guest suite in Tubac
Tubac Golf Resort Casita - central Tubac location
$95 per night
Guesthouse in Tubac
Casita in the Barrio
$78 per night