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Vacation rentals in Santa Cruz County

Find and book unique accommodations on Airbnb

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Top-rated vacation rentals in Santa Cruz County

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite

Guest suite in Tubac

Private Tubac Retreat under The Milky Way

A tranquil, spacious, and beautiful Casita. Comfortable King bed with a gel memory foam mattress, additional pillows and blankets for your convenience, private bathroom, microwave, small fridge, toaster, coffee maker, and teas and coffee for a quick bite. Private entrance and a small patio with seating area, which leads to the staircase to the roof where you can enjoy the view during the day and the Milky Way at night. Large screen TV with Netflix and Hulu (bring your own passwords), and Wi-Fi.

Jun 5 – 10

$75 per night$428 total
Guest favorite

Guest suite in Tubac

Tubac Golf Resort Casita - central Tubac location

The casita is centrally located between the Tubac Golf Course and Tubac village. Private outside entrance. Early check in and check out upon request. Private bedroom, bathroom. Large yard with outdoor kitchen with burner, sink, grill. Patio table with umbrella, and dog door. Casita has king-size bed, table and chairs. Amenities include WIFI, local TV, Netflix, Amazon Prime, coffee pot, microwave, and refrigerator with ice. Pool access at golf resort. Weekly and long stay discounts available.

Dec 10 – 17

$65 per night$551 total
Guest favorite

Home in Sonoita

The Adobe House - Historic Wine Country Getaway

The perfect home base for your wine tasting getaway! Our historic adobe is full of Arizona charm and minutes away from Elgin and Sonoita's wineries. Centrally located near the Sonoita Crossroads, the Adobe House is walking distance from local restaurants, including Copper Brothel Brewery and Tia 'Nita's Cantina. Owned + operated by the proprietors of Rune Wines. Please note that the Adobe House is located next door to the Winemaker's Casita. There is plenty of room for privacy, or book both!

May 21 – 28

$146 per night$1,226 total

Popular amenities for Santa Cruz County vacation rentals

Other great vacation rentals in Santa Cruz County

Guest favorite

Home in Sonoita

Under the Oaks

Dec 2 – 9

$146 per night$1,283 total
Guest favorite

Loft in Tubac

* New* Tubac Loft Studio Apartment

Jun 25 – Jul 2

$93 per night$809 total
Guest favorite

Guest suite in Tubac

2 RAVEN RANCH

Jan 30 – Feb 6

$90 per night$735 total
Guest favorite

Apartment in Tubac

Private, Unique, Central, 100% Solar+FreeEV Charge

Jun 21 – 28

$106 per night$844 total
Guest favorite

Guesthouse in Tubac

Amazing Casita at the Tubac Resort-Self check-in*

Oct 26 – Nov 2

$79 per night$689 total
Guest favorite

Townhouse in Tubac

Best Nest for Relaxing, Swimming & Birding

Jul 9 – 16

$93 per night$849 total
Guest favorite

Guest suite in Tubac

Adorable Casita with Pool

Aug 24 – 31

$104 per night$912 total
Guest favorite

Home in Nogales

Charming 4BD home with patio and big yard!

Jan 25 – Feb 1

$100 per night$867 total
Guest favorite

Guesthouse in Tubac

Cottage in the neighborhood

Apr 2 – 9

$79 per night$657 total
Guest favorite

Guesthouse in Patagonia

Mesquite Cottage

Sep 7 – 14

$89 per night$778 total
Guest favorite

Guesthouse in Tubac

Cottage Marquez

Jun 14 – 21

$92 per night$768 total
Guest favorite

Apartment in Sonoita

High Desert Wine Country

Jun 27 – Jul 4

$130 per night$1,090 total

Destinations to explore