Some info is shown in its original language. Translate

Vacation rentals in Panama City

Book unique vacation rentals, houses, and more on Airbnb

0 of 0 items showing
1 of 3 pages

Popular amenities for Panama City vacation rentals

Other great vacation rentals in Panama City

Guest favorite
Condo in Marbella
4.92 out of 5 average rating, 13 reviews

Oceanfront Condo at Yoo Panama

MariaRating, 5 stars1 month ago
Jeremy is a great host with a great property. The Yoo's central location in a very nice neighborhood is key to the experience. It's a very walkable area and the building has nice amenities. Being from Miami Beach and having lived in Paris, anything with Phillipe Starck's touch is extra special and the Yoo's public spaces are designed by him. Best feature of Jeremy's place: the unobstructed views of the bay. We can't wait to return.
Guest favorite
Apartment in Panama City
5 out of 5 average rating, 9 reviews

Apartamento Vista al Mar en la Cinta Costera

OmarRating, 5 stars3 days ago
Un alojamiento muy comodo y acogedor con todo lo que necesitas para una estancia placentera. Refrigerador, Microondas, Lavadora y Secadora, Plancha, etc. El apartamento esta muy bien ubicado en la zona céntrica y costera de la ciudad con muchas areas de interes cercanas. El edificio es de facil acceso y cuenta con alberca. Muy bonita vista desde las ventanas
Guest favorite
Apartment in Panamá
4.93 out of 5 average rating, 27 reviews

Casco Viejo 2BR Loft • Rooftop Pool Gym & Balcony

JohnRating, 5 stars1 week ago
This Airbnb is perfectly located at the entrance of Casco Viejo, just steps away from some of the best restaurants, bars, and pubs in the area. With two bedrooms, each with its own private bathroom, it was definitely a great value. Plus the high ceilings in the living room add a lovely charm and spacious feel to the place. Will definitely come back if I visit Panama again :)
Top guest favorite
Apartment in Panamá
4.98 out of 5 average rating, 63 reviews

Céntrico, elegante y minimalista

AlessandraRating, 5 stars3 weeks ago
The flat was exactly as described. It was very cosy with hot water and in a great area. Jesús was extremely responsive and helpful. It was a great place to stay for a city break.
Top guest favorite
Apartment in Panamá
5 out of 5 average rating, 67 reviews

Apartamento Nuevo en calle 50

ShawnteRating, 5 stars1 week ago
Hi Tonio, Thank you so much for a wonderful stay! Your place was exactly what I needed clean, comfortable, and in a perfect location. I really appreciated the thoughtful touches and how easy everything was from check-in to check-out. It truly felt like a home away from home. I’d definitely love to stay again next time I’m in the area. Thanks again for your hospitality! Thank you, Tae
Guest favorite
Apartment in Costa del Este
4.97 out of 5 average rating, 31 reviews

Penthouse Vista Panorámica con Amenidades de Lujo

MichaelRating, 5 stars1 week ago
Would recommend for a vacation, clean and the host was very helpful with our check in. Comfortable and safe feeling location, there is also a food hub right across the street so that’s a plus.
Guest favorite
Apartment in Panama City
4.94 out of 5 average rating, 50 reviews

19L Breathtaking Oceanview Playa Bonita Resort

TammieRating, 5 stars2 weeks ago
Nice place and views and there was a local store for any food needs. The place was 30-40 minutes from the downtown of Panama and traffic was terrible getting to Panama. But the condo made up for the headache of the traffic we looked forward to coming back to our temporary home. Thanks for allowing my family and I to stay at your villa.
Guest favorite
Apartment in Panamá
4.85 out of 5 average rating, 20 reviews

Villas La Fontana Spacious ApartaSuite - Pool 102

WillRating, 5 stars2 weeks ago
Un séjour parfait ! Le logement était impeccable, très propre et bien entretenu. Tout est pensé pour passer un moment agréable : le lit est super confortable, l’endroit est calme tout en étant proche de tout (commerces, transports, restaurants…). On s’y sent bien dès l’arrivée. Je recommande les yeux fermés et je n’hésiterai pas à revenir !

Quick stats about vacation rentals in Panama City

  • Total rentals

    4.5K properties

  • Nightly prices starting at

    $10 before taxes and fees

  • Total number of reviews

    103K reviews

  • Family-friendly rentals

    1.5K properties are a good fit for families

  • Pet-friendly rentals

    1.5K properties allow pets

  • Rentals with a pool

    2.4K properties have a pool

Frequently Asked Questions

  • How is the weather in Panama City?

    Panama City has a tropical climate with high temperatures throughout the year, usually ranging from 75°F to 88°F (24°C to 31°C). Rainy season occurs between May and December, while the dry season extends from January to April.

  • What are some of the best things to do in Panama City?

    Popular activities in Panama City include exploring the historic Casco Viejo district, visiting the Panama Canal Museum, and strolling along the Cinta Costera. Birdwatching in the Metropolitan Natural Park and shopping in the Mercado de Mariscos are also often recommended.

  • What is the best time of year to visit Panama City?

    The most frequented time to visit Panama City is between January and April. This period coincides with Panama's dry season, which enables more comfortable exploration of the city's many attractions. During this time, the vibrant and lively Carnival of Panama, typically held in February, draws a sizable crowd.

  • What are the best places to stay in Panama City?

    Casco Viejo, the city's historic district, is a popular area to stay in Panama City due to its colonial architecture and range of dining options. The modern neighborhood of Punta Paitilla is often recommended for its skyscrapers and shopping centers, while Costa del Este appeals to those seeking a quieter, residential ambiance.

  • What are the best places to visit in Panama City?

    Many visitors to Panama City enjoy the historic district of Casco Viejo, the Panama Canal, and the Metropolitan Natural Park. Other frequently suggested places include the Amador Causeway for its stunning views, and the Biomuseo for its distinct architecture and exhibits on biodiversity.

  • What are some hiking trails in Panama City?

    The Metropolitan Natural Park, located within Panama City, has several hiking trails, such as the Mono Titi Road and the Los Momotides trail. Just outside the city, you can explore the trails of the Soberania National Park, including the Pipeline Road, known for its diverse birdlife.

  • What are some family activities to do in Panama City?

    Families in Panama City often enjoy a visit to the Biomuseo, a museum renowned for its exhibits on biodiversity. The Panama Canal, particularly the Miraflores Locks, provides an educational experience. The Metropolitan Natural Park and Summit Botanical Gardens and Zoo are also popular destinations for families.

  • What are some of the best day trip ideas in Panama City?

    A day trip to the Panama Canal, specifically the Miraflores Locks, is frequently suggested. The beautiful Pearl Islands are also accessible for a day trip from the city. Within the city, exploring the historic district of Casco Viejo, or the biodiversity of the Metropolitan Natural Park, make for enjoyable day trips.

  • Are there vacation rentals with a dedicated workspace in Panama City?

    Yes! Work meets play with ease at over 2,560 vacation rentals in Panama City featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Are there pet-friendly vacation rentals in Panama City?

    Four-legged friends are welcome in Panama City. Choose from more than 1,510 vacation rentals for guests traveling with pets.

Destinations to explore

  1. Airbnb
  2. Panama
  3. Panamá Province
  4. Panama City