
House vacation rentals in Mesilla
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Top-rated house rentals in Mesilla
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
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Popular amenities for Mesilla house rentals
House rentals with a pool

Home in Las Cruces
4.83 out of 5 average rating, 70 reviewsBriarwood Place (with Game Room and Pool)
Phenomenal Host! Excellent communication, quick to respond, kind, friendly, understanding and so very accommodating. This home was perfect for our family’s holiday vacation. Beautiful, comfortable home, fully loaded with everything we could possibly need. We truly appreciate you letting us stay in your home !

Home in Las Cruces
4.92 out of 5 average rating, 292 reviewsCasita at the Mediterranean Palms Estate
Very nice place to stay! Everything is good quality and the upstairs room was perfect for our kids.

Home in Las Cruces
5 out of 5 average rating, 9 reviewsCozy Desert Escape Pool & Game Room
“Fantastic stay! The property was spotless, with a beautiful pool and plenty of activities to keep us entertained. The location was perfect, and the host was super responsive and welcoming. Highly recommend for a fun and relaxing getaway!”

Home in Las Cruces
4.84 out of 5 average rating, 19 reviewsDesert Oasis Pool & Urban Orchard w/Tesla Charger
Daniel was very nice. There was a bit of confusion at check in. He had set up a timed delivery for the code that i did not get and I could not get a response because he was in a meeting. Totally understandable. In our situation it was not a big issue. The house was perfect for our needs. We were staying with several family members for a relative's funeral. The beds were very comfortable. The house was beautiful and well thought out, with everything that we needed for our stay.

Home in Las Cruces
5 out of 5 average rating, 36 reviewsDesert Paradise, with hot tub
This beautiful house is in a nice quiet neighborhood, easy to find, and close to shopping and restaurants. Kitchen was well stocked, beds were comfortable, and we had no issues at all! Las Cruces weather did not cooperate (two days of snow and cold temps in the 20s) to use the gorgeous backyard patio, pool and hot tub but there’s a easy to use gas fireplace in the living room that warmed us up. We were here for the races at Vado which was an easy drive! We will rebook next time!!

Home in Las Cruces
4.97 out of 5 average rating, 111 reviewsDesert Oasis with Pool
The place was extremely clean and very well maintained. Everything looked exactly like described with private and peaceful surroundings. Will definitely come back.

Home in Las Cruces
4.89 out of 5 average rating, 151 reviewsDesert Pool Oasis-Central Location-Family Friendly
I don't believe I can put all of the positives in this review. We utilized the entire home, which was immaculately clean, fully stocked kitchen, comfortable furniture, plenty of entertainment and all the necessities for the pool and even slefs to take to white sands. Host was extremely responsive and fair. We would love to stay here in the future.

Home in Las Cruces
4.86 out of 5 average rating, 7 reviewsNew Listing! Relax & Rejuvenate: Pool, Sauna & Gym
Beautiful house! Very comfortable and clean. We spent Thanksgiving here with family and the house met all expectations.
Weekly house rentals

Home in Las Cruces
4.95 out of 5 average rating, 194 reviewsCozy & Comfortable New Mexico Home
Clean, comfortable home, nice for a family traveling with a small dog. Neighborhood felt safe. Easy to get in and out, and garage parking is available

Home in Las Cruces
4.96 out of 5 average rating, 103 reviewsCozy Mountain View near White Sands
Couldn't have asked for a more understanding and flexible host, some family issues had come up and we needed to extend our stay, Lori was understanding and awesome, we can't thank you enough, our stay was awesome the home was cozy and relaxing, 10 outta 10 highly recommend

Home in Las Cruces
4.76 out of 5 average rating, 17 reviewsThe Perfect Home
We had a great stay at Daniele’s place! The neighborhood is quiet and lovely. Our two medium/large dogs loved the backyard, and the master bedroom and bathroom were excellent!! We really enjoyed our stay and would love to stay here again if we found ourselves in Las Cruces.

Home in Las Cruces
4.88 out of 5 average rating, 34 reviewsYour modern home away from home 3BR 2 BTH
Great place to stay- Everything was in good working order. Monster TV!! Comfortable beds. didn't use the grill or outside but it was as described. would highly recommend!

Home in Las Cruces
5 out of 5 average rating, 11 reviewsRelaxing Hot Tub + Family Friendly Cozy Home
This home is great. The furnishings are complete and high quality. The furniture was super comfortable. I love the cow foot stool. The bed was really nice and comfortable. The shower was amazing. One of the best showers I’ve ever had in an Airbnb. The hot tub was very nice and clean. Overall this is a great place. The owners really know how to furnish and provide a great experience for their guests. I will stay here again and again.

Home in La Mesa
5 out of 5 average rating, 4 reviewsSpacious Southwest Hacienda
From check in to check out our stay was amazing ! Our host Derek was super responsive and went above and beyond to accommodate us! I highly recommend booking this lovely home!

Home in Las Cruces
4.92 out of 5 average rating, 84 reviewsSpacious Southwest Retreat. king bed!
This was the perfect spot for my husband and I to visit with our family. It was bigger in person than the pictures show, which was a pleasant surprise. Highly recommend

Home in Las Cruces
4.83 out of 5 average rating, 157 reviewsVIGIL-INN High Desert Escape in Quiet Neighborhood
This is the third long-term stay I’ve had at Mark‘s house. It is absolutely beautiful and comfortable and clean. Mark is a wonderful host who is friendly and responsive and helped troubleshoot multiple issues that came up during my stay. The neighborhood is quiet and we love using the basketball and tennis courts around the corner. His place is nearby a number of playgrounds and green areas for kids and a short drive from lots of amenities! Highly recommended!
Private house rentals

Home in Las Cruces
4.9 out of 5 average rating, 60 reviewsCasa Sonoma | Pet Friendly, Modern | Peloton
This stay far exceeded our expectations. Very peaceful settings - pristine conditions

Home in Las Cruces
4.91 out of 5 average rating, 65 reviewsLotus Blossom: serene, quiet, relaxing!
This was my 2nd time staying here. I would recommend this if your in the area.

Home in Las Cruces
4.92 out of 5 average rating, 61 reviewsSouthwestern Comfort Stay 2
The house is stunning and very well decorated. The kitchen is fully stocked with anything a cook might want or need. He has nice furniture. Gorgeous decorations. The master bath is amazing. Love the backyard. The location is secluded but close to mesilla.

Home in Las Cruces
4.99 out of 5 average rating, 145 reviewsModern Luxury Home
Arlene and her husband were excellent hosts. They were quick to respond and made me feel welcome. This is a beautiful home, in a quiet neighborhood. It was immaculent, with well equipped kitchen and bathrooms, games inside and outside, nice patio, and great wifi connection. I had a comfortable stay and will definitely look forward to a return stay on my next visit.

Home in Las Cruces
5 out of 5 average rating, 36 reviewsCozy Las Cruces Home
very clean, quiet neighborhood

Home in Las Cruces
5 out of 5 average rating, 55 reviewsEntire Home- Vista Montaña (your White Sands Base)
Loved our stay. Erika was prompt with her replies and was very accommodating to our needs. Would definitely stay again when in the area.

Home in Las Cruces
4.99 out of 5 average rating, 88 reviewsBonita Chiquita Casita
This was probably the best Airbnb I’ve ever stayed in. It was clean, they had everything I could need and I loved the decor. It was absolutely perfect and Jeff was a great host. I highly recommend it! 5-stars!

Home in Las Cruces
4.85 out of 5 average rating, 13 reviewsSweet Escape with Spa bath
Krystal’s home was great. It had a beautiful view of the Organ Mountains, which is something I look forward to seeing when I come to Las Cruces. The home was easy to locate and close to several restaurants, grocery stores, and in a safe neighborhood. She had a lot of the small details covered.
Quick stats about house rentals in Mesilla
Total rentals
30 properties
Nightly prices starting at
$60 before taxes and fees
Total number of reviews
2.1K reviews
Family-friendly rentals
10 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with dedicated workspaces
10 properties have a dedicated workspace
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