Vacation rentals in Mesa County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Mesa County

Guests agree: these stays are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Superhost

A welcoming porch is framed by rustic branches, offering a shaded area for relaxation. A swinging bench with decorative pillows invites guests to enjoy the outdoors. Natural stone flooring complements the earthy design, enhancing a cozy atmosphere while blending with the surrounding landscape.

Farm stay in Glade Park

4.86 out of 5 average rating, 600 reviews

Cozy Rustic Colorado Cabin!

Cozy Rustic Cabin, located on a working horse ranch on top of the Colorado National Monument, 30 min from Grand Junction, CO. This location is perfect for those seeking a unique place to stay while enjoying all the adventures available around the area including hiking trails, horseback riding, ATV riding, hunting, and some of the best mountain biking around. There is beautiful aspen covered,alpine high country nearby as well as red rock desert/ formations including a series of natural arches.

Top guest favorite

A rustic carport features a vintage vehicle with weathered paint, under a metal roof. An American flag hangs from one post, while colorful hanging planters add a touch of greenery. The surrounding open area is dotted with sparse grass and low shrubs.

Home in Orchard City

4.95 out of 5 average rating, 539 reviews

The Orchard House

**A devastating freeze in October 2020 killed all 400 of our sweet cherry trees and many of our peach trees. Sadly, our orchard is not the lush green jewel it once was. We are planting new cherry trees in the Spring of 2022. While the orchard views have changed, the Orchard House continues to offer a very comfortable place to rest and recharge. Come enjoy fresh air and quiet whether you are stopping through on a road trip or staying longer for local adventure. Fast WiFi for telecommuting!

Guest favorite

The interior features warm wooden paneling and natural light from the windows. A cozy sofa sits across from a kitchenette with a mini-fridge and coffee setup. A handcrafted iron ladder leads to the lofted sleeping area, which includes a comfortable queen bed.

Tiny home in Hotchkiss

4.95 out of 5 average rating, 400 reviews

Tiny House Farm Stay w/Kitchenette *Black Canyon*

This cute & cozy tiny house on Fire Mountain Farmstead has easy access to the area's many attractions. Right on Hwy 92, its 7 minutes to downtown Hotchkiss and 20 min to Paonia. Drive 45 min to the Black Canyon's North Rim, or 45 min the other direction to the Grand Mesa. World class fishing is right down the road! The scenic North Fork Valley is surrounded by public land for hunting and adventure. Well-stocked kitchenette. 100 Mbps WiFi. Dog allowed. No cats. Smoking OK outside, 420 friendly!

Top guest favorite

A southwestern adobe-style house is framed by lush, lavender-colored plants and smooth stone borders. The structure features warm, earthy tones with distinct architectural details and a welcoming entrance. The sky above holds a mix of clouds, contributing to the serene atmosphere.

Guest suite in Hotchkiss

4.99 out of 5 average rating, 198 reviews

Top of the Mesa Lookout Tower

Centrally located in the Grand Valley, on the edge of a Redlands Mesa, sits our Southwestern adobe style house. An outside staircase takes you up to the tower guest room. There is ample parking and a culdesac. It's fisherman friendly with a turn around driveway to accommodate dories or rafts. The valley is known for its orchards, wineries and vineyards. Explore the Black Canyon of the Gunnison National Park. If you like getting away to a peaceful and quiet retreat, this is the place for you.

Top guest favorite

A covered porch is supported by wooden beams, featuring outdoor seating arranged on a textured rug. Large windows reflect the golden hour light, blending the indoor and outdoor spaces. Scenic views extend beyond the deck, highlighting the natural surroundings.

Guesthouse in Cedaredge

4.98 out of 5 average rating, 191 reviews

Yonder Mountain Retreat

A beautiful guesthouse on 5 acres a few miles north of the quaint town of Cedaredge. Multiple access points to the Grand Mesa, the ultimate outdoor playground for snowmobiling, hiking, motorcycling, ATVs, UTVs, fishing & hunting! Extra parking for motorcycles, ATVs, UTVs, or snowmobiles! YMR permits guests to bring one furbaby without pre-approval ($100 pet fee still applies). To bring more than one pet, pre-approval & addt’l. fees apply. One external security camera by the kitchen door.

Top guest favorite

A contemporary home is presented with a wooden exterior, surrounded by a gravel area. Large glass doors offer views into the interior space. Two outdoor chairs are positioned on the patio, with wildflowers and vegetation framing the scene.

Home in Loma

5 out of 5 average rating, 599 reviews

Fruita/Loma Guest House at the Perfect Day Getaway

This newly constructed "Green" home is a mix of modern and country styles and will surely inspire you to enjoy all of the outdoor activities the Grand Valley has to offer. The Perfect Day Getaway house is located on a quaint farm within 8 minutes of world-class hiking, mountain and road bicycling, and river rafting. It is a great launching point for day trips to Moab and the Grand Mesa as well! It was built to maximize the southern exposure and views of the Colorado National Monument.

Top guest favorite

A modern house is set against a clear night sky filled with stars. The exterior features large glass doors, providing a seamless view of the surroundings. A spacious patio area is visible, bordered by natural landscaping, creating a sense of tranquility and connection to nature.

Home in Palisade

4.98 out of 5 average rating, 130 reviews

Rapid Creek Retreat

High above the town of Palisade, nestled in the foothills of the Grand Mesa, is the Rapid Creek Retreat. Surrounded by untouched public land you will experience the true gift and grit of Colorado. Enjoy views of the big sky from sunrise to sunset and beyond for magical star gazing. We planned for this home to be ours, every detail of this home was built with intent and love. The feeling here is truly special. For those ‘rough around the edges. Sincerely, The Busch’s

Guest favorite

An A-frame cabin is showcased against a snowy landscape, with its striking angular roof matching the nearby mountain backdrop. Large windows reflect the winter scenery, while seating is provided on the porch. The serene environment is enhanced by the natural rocky terrain surrounding the structure.

Place to stay in Mesa County

4.95 out of 5 average rating, 285 reviews

Thimble Rock Point

Nestled in the mountainside of an obscure Colorado canyon there is a place so fitting it literally rises from the rock the way a ship breaks a wave. Mimicking the geology and angular unconformity of the canyon walls, a harmonic relationship exists between roof pitch and steep granite cliffs. Built for the traveler who seeks more than shelter but an experience, the magic at Thimble Rock will evoke feelings of nostalgia, romance and the yearning to explore.

Top guest favorite

The exterior of the property features a unique stone façade, complemented by a tiled roof. Surrounding landscaping includes gravel pathways and shrubbery, with towering red rock formations rising in the background under a vibrant sky. Large windows are visible, allowing for scenic views.

Apartment in Grand Junction

4.99 out of 5 average rating, 190 reviews

Luxury Apartment at Castle MVP - Sleeps 4!

THIS IS NO ORDINARY AIRBNB! Monument Vista Place is located just 3 miles from the I-70 freeway, and the quaint town of Fruita Colorado. Gated, safe and quiet, MVP offers EPIC views of Colorado National Monument! We are pet friendly because we know the challenges of traveling with our fur babies. We welcome responsible, like-minded, pet owners. Come enjoy a restful and luxurious stay, whether you're just traveling through or looking for a get-a-way!

Guest favorite

A spacious bedroom features a light-toned bed with textured bedding against a backdrop of vertical wood slats. Soft curtains frame a window, and a modern pendant light hangs above. A bedside table with lamps complements the area, alongside a stylish chair and a decorative rug.

Guesthouse in Palisade

4.94 out of 5 average rating, 220 reviews

Wine Country Getaway - 10 Acres w/ stunning views

Escape to this luxurious upstairs suite on 10 private acres, featuring a king bed, large kitchen, wrap-around porch, panoramic vineyard views, and lots of extra space. Just 5 minutes from Palisade’s wineries and dining, and 40 minutes to Powderhorn Ski Resort. Ideal for couples seeking a romantic getaway or ski retreat. Modern amenities, Wi-Fi, stunning sunsets, and incredible stars make it a perfect year-round destination. Your hosts, Joe & Trish

Top guest favorite

A circular seating area made up of four wooden chairs surrounds a stone fire pit, set on a gravel base. Lush green grass and various trees provide a natural backdrop, while sandstone formations rise in the distance under a clear blue sky.

Guesthouse in Grand Junction

4.99 out of 5 average rating, 353 reviews

Chic 2 Bedroom Cottage with Monument Views

Mountain biking, hiking, motorcycling? It's all right here! Our newly built 2 bedroom private cottage sits at the base of Colorado National Monument and is thoughtfully designed to help you relax and unwind. Ride out the back door or take a short drive to the legendary trails of Grand Junction and Fruita. When the fun is done, rest your legs on your secluded patio and watch the sunset over the sand stone towers looming in the backyard.

Top guest favorite

The solargon is viewed from a distance, showcasing its octagonal shape and outdoor seating area. A covered porch with chairs and a small table is situated next to the entrance, along with a grill for outdoor cooking. Surrounding greenery adds a natural feel.

Tiny home in Hotchkiss

5 out of 5 average rating, 676 reviews

The Solargon

The Solargon is inspired by elements of Asian yurts, Navajo hogons and Native American hidatsa lodges. Combined with passive solar design principles, the solargon is an octagonal structure designed to take full advantage of the sun. The vaulted ceilings and plentiful windows make the solargon bright and inviting. This is a perfect spot for solo travelers or couples looking for a quiet, off the beaten path place to get away from it all.