Vacation rentals in Lee County

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Top-rated vacation rentals in Lee County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite

A closed-in porch features a combination of seating options, including a dark wicker sofa and armchairs. A small table sits on the tiled floor, accompanied by decorative plants. Light enters through the windows, illuminating the brick walls and creating a comfortable gathering space.

Home in Mayesville

4.88 out of 5 average rating, 16 reviews

The Mayesville - Sumter-Florence Family Getaway

Newly renovated Home in quiet Mayesville, SC. is close to Sumter, Florence, Bishopville, Lake City, Lynchburg and Interstates 95 and 20. This is the perfect vacation spot for families reuniting for reunions, visiting relatives, day visits to Myrtle Beach, and just to get away. This home sports 2 closed in porches, 3 bedrooms, 8 beds, laundry room and yard for play area. If you don't want to be cramp up in a 1 room hotel and want to enjoy your family from a distance, this home is perfect.

Superhost

The kitchen showcases wooden cabinetry with a mix of open shelving and closed storage. A stainless steel dishwasher and sink are located under a window, while countertop appliances and utensils are organized on the counters. Natural light fills the space, enhancing the warm wood tones.

Home in Hartsville

5 out of 5 average rating, 7 reviews

Calm older home near W Carolina roundabout

Just right for your Hartsville area stay. Older home that is a good fit for professionals and other travelers looking for a short term place. NOT able to walk to lake. Lake IS located 6 miles away. Hardwood floors, large capacity refrigerator, dedicated office, and den area make this place good for a variety of travelers. A home to accommodate you when you come to town for work, play, family visits, medical procedures, end of life events, weddings, new family baby, temporary assignments, etc.

Guest favorite

Cabin in Hartsville

5 out of 5 average rating, 61 reviews

Cozy Log Cabin retreat on a farm.

2 BR 1 Bath log cabin built in 2016 sitting on 100 acres of beautiful farmland surrounded by horse pastures, crop fields, gigantic pecan trees that line the 1/4 mile gravel drive and woods. Sit on the screened front porch in the morning, sipping coffee and watch the horses grazing peacefully in the pasture. Serene retreat for those looking for a secluded area to just get away from it all for a while. Please check out our Guest Book for local Businesses, restaurants and things to do in town.

Top guest favorite

A modern kitchen is showcased, featuring a polished wooden countertop and an elegant blue cabinetry. A stainless steel refrigerator stands beside a microwave, and a four-burner stovetop with a griddle is centered on the island. Natural light enters through a nearby window.

Home in Camden

5 out of 5 average rating, 13 reviews

Twin Cedars - less than a mile to Broomsedge Golf!

Incredible Retreat in Camden! Enjoy this perfect country escape, just 15 minutes from Camden and less than 1 mile from the new Luxury Broomesedge Golf Course! This newly remodeled home offers modern comforts in a peaceful setting, complete with access to a Tesla charger and the option for guided hunting tours on privately owned acreage. Located only 20 miles from Shaw Air Force Base, it’s ideal for golfers, families, or anyone seeking a quiet getaway in nature with beautiful horizon views.

Superhost

A well-equipped kitchen features a granite countertop with a sink positioned beneath a set of double windows, allowing natural light to enter. Essential appliances include a microwave and stovetop, while a coffee maker adds convenience. White cabinetry complements the overall brightness.

Home in Hartsville

5 out of 5 average rating, 9 reviews

Roomy 2BR Hartsville Home

Come stay at our roomy 2 bedroom 1 bath Hartsville home. Each bedroom has one queen size bed sleeping 4 guests total. Located 7 minutes from downtown Hartsville and Coker University, this home is the perfect place for your stay in Hartsville. Additionally, this home sits 6 minutes from Sonoco, 11 minutes from Duke energy nuclear plant, 2 minutes from Carolina pines hospital, and 23 minutes from Nucor, making this home ideal for traveling workers. (Travel times may vary based on traffic)

A spacious living area features wooden floors and a neutral color palette. Two comfortable armchairs are positioned near a wooden coffee table, with a television mounted above a decorative fireplace. A staircase with wooden steps leads to the upper level, accompanied by a potted plant.

Home in Sumter

4.76 out of 5 average rating, 17 reviews

Carolina Manor

Unique beautiful split level 5 bedroom 3/ bathroom home on a corner lot. The Spacious home is conveniently located 12 minutes from Shaw AFB and close to multiple highways and downtown Sumter. A large front lawn and back yard perfect for a getaway for friends and family. Home has fully equipped kitchen with cookware and all new stainless steel appliances, 2-car Garage, laundry room all amenities of home, and new beautiful furnishings. Don’t miss this well curated home.

Superhost

A dining area is highlighted by a wooden table surrounded by six chairs. A floral centerpiece decorates the table, while a chandelier hangs overhead. Natural light filters through a large arched window, illuminating the space in soft tones.

Home in Sumter

4.8 out of 5 average rating, 20 reviews

(#5) Alluring Away home (No cleaning fee)

Home away from home perfect for families looking for a peaceful and safe neighborhood! Modern 3 bedroom, 2 bath home away from home 5 mins away from town. This home includes a living room perfect for family time supplied with a smart tv perfect for watching movies, a backyard patio with shade away from the sun and lights to set the vibe, a kitchen with basic cooking essential and a Keurig coffee station to make delicious coffee in the mornings. As well as a laundry room!

Top guest favorite

A cork board map of the United States is displayed on a wall. Each state is labeled with its name, some illustrated with icons and symbols. The design includes Alaska and Hawaii, and features a light-colored background that enhances the visibility of the map.

Home in Hartsville

4.97 out of 5 average rating, 117 reviews

Cozy little home away from home

This little gem is sure to make you feel at home! Our Barefoot Bungalow sits on a quiet residential street just 3 minutes from downtown Hartsville. The beds are comfortable, the couch is just waiting for you to settle in, and the kitchen was set up by two people who LOVE to cook. There's even an outdoor space to have a quick meal or enjoy the cool of the evening. This is my little dream cottage and I am so happy to be able to share it with you!

Guest favorite

A modern kitchen featuring blue walls and a spacious granite countertop with three wooden stools. Upper cabinets display glass doors, showcasing kitchenware. Stainless steel appliances, including a refrigerator and oven, are positioned against the wall, highlighting a fresh and functional cooking space.

Home in Sumter

5 out of 5 average rating, 9 reviews

Townhome near Shaw AFB/Medcenter

Relax with the whole family at this peaceful place to stay. This is an end-unit 3 Bedroom 2.5 bathroom townhome 5 min from Shaw AFB and 10 min from downtown Sumter/medical center. 2 queen beds and 1 full bed and each room is equipped with a smart TV. Basic cooking and dining necessities are also included.

Top guest favorite

A cozy living room is presented, featuring a comfortable sectional sofa and two armchairs arranged around a wooden coffee table. A ceiling fan provides circulation, and a decorative fireplace serves as a focal point. Natural light filters in through windows, enhancing the welcoming ambiance.

Home in Dalzell

4.96 out of 5 average rating, 140 reviews

Home away from home

Forget your worries in this spacious and serene space. A quiet neighborhood conveniently located close to Shaw Air Force base and within minutes to major hospitals and shopping. Please read: If you have more than two pets you will need to be pre approved. Pet fee is $15 per pet / stay