Skip to content

Vacation rentals in Lee County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Lee County

Guests agree: these stays are highly rated for location, cleanliness, and more.

Superhost
Cottage in Sumter
Restful Lakeside Getaway Cottage -Dogs allowed.
This pond-side cottage is a peaceful place to relax and unwind. Sit on the enclosed porch and watch the water or enjoy the front porch swing where you can listen to the birds and frogs. We are 12 min. from downtown Sumter and 20 min from Shaw AFB. Local points of interest are Swan Lake Iris Gardens and Poinsett State Park. It is only 2 hours to Myrtle Beach and Charleston, SC & 3 hrs to the mtns. While it is conveniently located, this cottage offers a quiet place to put your feet up and rest.
$99 per night
Superhost
Guesthouse in Camden
Red Roof Loft @ FireFly Farm
Come enjoy wide open quiet spaces on our almost 30-acre farm. If you need time and space to unwind, you will find that here. Our farm includes 1 rescue Lionhead bunny, 2 rescue cats, 2 rescue dogs, a flock of chickens (fresh eggs please!!) and a few horses. If you are NOT an animal lover, Firefly Farm might not be a good fit. One of our cats, Marshmallow, will sometimes make the top of your vehicle her little resting place. And if you leave your door open, she might just jump right in!
$93 per night
Superhost
Guesthouse in Florence
The Poolside Cottage: Close to Interstates
New floors and paint in January of 2023. Palm Trees, colorful flowers, hammocks and quiet space await in this tropic-like oasis just minutes from I-95/20. Hundreds of reviews acknowledge this idyllic setting. We are a Florence Airbnb favorite for travelers. We offer a queen bed, full bathroom, queen sleeper sofa, strong wifi and TV. We even provide breakfast bars and coffee to help you jump start your day as you set off for the next journey. We look forward to hosting you.
$102 per night

Other great vacation rentals in Lee County

Superhost
Guest suite in Camden
The Red Cedar Studio
$90 per night
Superhost
Guesthouse in Florence
*No Cleaning Fee* Private Downtown Stay Near I-95
$87 per night
Superhost
Home in Sumter
Bungalow on Bobs
$95 per night
Superhost
Cottage in Timmonsville
*Cottage Near Florence and I-95*
$101 per night
Superhost
Apartment in Camden
Camden Carriage House on the Polo Field
$95 per night
Superhost
Guest suite in Florence
Private Apartment 5 Min Away From I-95 & I-20
$75 per night
Superhost
Guesthouse in Florence
Midtown Retreat - Guest House in heart of Florence
$99 per night
Superhost
Home in Bishopville
The Blue Door House
$97 per night
Superhost
Cottage in Hartsville
Cozy Blue Cottage 2BR/1BA
$114 per night
Superhost
Guesthouse in Camden
Camden Cottage
$100 per night
Superhost
Apartment in Hartsville
Centennial Park Loft - 1 Bed/1Bth - Dwntwn Hville
$120 per night
Superhost
Home in Sumter
A Front Porch Made for Rocking!
$145 per night

Destinations to explore